最大密度投影对CT肺癌普查小结节检出的影响  

Advantage of Maximum Intensity Projection in the Detection of Small Pulmonary Nodules at Low-dose CT

作　　者：柳学国[1] 梁明柱[1] 王勇[1] 陈翠芬[1] 秦培鑫[1] 何燕丽[1] 

机构地区：[1]中山大学附属第五医院放射科,广东519000

出　　处：《放射学实践》2008年第10期1096-1099,共4页Radiologic Practice

摘　　要：目的:对比最大密度投影(MIP)、单纯薄层(TS)和两者结合3种阅片方式对肺癌低剂量CT普查小结节检出的差异。方法:以TS、MIP、MIP+TS阅读连续100例低剂量CT肺癌普查者图像,分别记录肺结节的总数,并且根据密度(实性、部分实性、非实性)、大小(≤4mm,>4mm)、部位(紧靠血管、远离血管胸膜、紧贴胸膜)进行分类比较。结果:MIP发现结节总数明显多于TS(85:38,P=6.8136E-9);前者发现实性(79∶28,P=3.5279E-11)及部分实性结节多于后者(4∶3),非实性结节少于后者(2∶7);前者对>4mm和≤4mm结节的优势均明显(21∶13与57∶15,P<0.05);前者对不同部位结节的检出率均能提高,其中紧靠血管结节(17∶5,P=0.0113)与非紧靠血管胸膜结节(54∶22,P=0.0162),均高于贴胸膜结节(14∶11);MIP+TS发现的结节比后两者多。结论:MIP+TS可以提高低剂量CT肺癌普查小结节的检出率。Objective：To compare thin slices （TS） ,maximum intensity projection （MIP） and MIP＋TS in the detection of small pulmonary nodules in low-dose CT screening for lung cancer. Methods：The CT images of consecutive 100 people participating in low-dose CT screening for lung cancer were read by MIP,TS and MIP＋TS respectively （time gap one week）. The total numbers of nodules found by the three reading styles were recorded and categorized according to different density （solid, part-solid, non-solid）, location （juxta vascular, non- pleural or vessel contacting, juxta-pleural） and size （≤4mm,〉4mm）. Results：More nodules were found by MIP than TS （85：38,P=6. 8136E-9） ,more solid nodules （79：28, P=3. 5279E 11） and part-solid nodules （4： 3） were found by MIP,less non-solid nodules were found by MIP （2： 7）;The nodule detection of different sizes were all improved markedly by MIP （ ≥4mm.. 21 ： 13, P= 0. 026857 ; 〈4mm： 57 ： 15, P= 7. 3025E-8）;MIP increased the nodule detection rates in different locations, more nodules of jaxtavascular （17：5, P= 0.0113） and non pleuralor vessel contacting （54：22,P 0.0162） were found than those ofjaxta- pleural （14：11）;more nodules were found by MIP＋TS than by TS or MIP. Conclusion： More nodules can be found by TS＋ MIP reading style in low-dose CT screening for lung cancer.

关 键 词：肺肿瘤 硬币病变 肺 最大密度投影 体层摄影术 X线计算机 

分 类 号：R734.2[医药卫生—肿瘤]