青少年空腹血糖受损与体脂分布的关系  

Relationship between impaired fasting glucose and fat distribution in adolescents

作　　者：刘晓丽[1] 陆强[1] 谢永红[1] 玄续敏[1] 陈泓[1] 王敏[1] 曹晓斌[1] 尹福在[1] 

机构地区：[1]河北医科大学附属秦皇岛市第一医院内分泌科,066000

出　　处：《中华健康管理学杂志》2008年第5期275-277,共3页Chinese Journal of Health Management

基　　金：河北省科技厅科技支撑项目（072761528）

摘　　要：目的探讨青少年空腹血糖受损（IFG）与体脂分布的关系。方法通过分层整群随机抽样，测定3874例13～18岁青少年身高、体重、腰围、臀围和空腹血糖（FPG）水平，通过问卷调查了解其父母糖尿病患病情况。根据FPG水平，分为空腹血糖正常组（FPG〈5．6mmol／L，n=3738）和空腹血糖受损组（5．6mmol／L≤〈FPG〈7．0mmol／L，n=136）。结果两组间各体脂指标比较，应用协方差分析校正性别、年龄后，空腹血糖受损组体重指数、腰围、腰围／身高比和腰臀比均高于空腹血糖正常组，组间比较差异有统计学意义（P〈0．05）。应用偏相关分析校正年龄、性别后，BMI、腰围、腰臀比及腰围／身高比均与FPG呈正相关（P〈0．05），其中腰围／身高比的r’值最大（r’=0．0925）。对FPG的多元线性回归分析，最佳模型引入年龄（β=-0．102，P〈0．05）、糖尿病家族史（β=0．186，P〈0．05）和腰围／身高比（β=0．842，P〈0．05）。结论中心性肥胖与青少年空腹血糖受损关系密切，腰围／身高比是描述青少年中心性肥胖的有效指标，是青少年空腹血糖受损的独立危险因素。Objective To investigate the relationship between impaired fasting glucose（IFG） and the distribution of body fat in adolescents. Methods Stratified cluster sampling was used to select 3874 adolescents aged 13-18 years for this cross-sectional study. Measurements included height, weight, waist circumference, hip circumference and fasting plasma glucose （FPG）. Family history of diabetes was determined by using a self-administered questionnaire. Participants were divided into normal fasting glucose group （ FPG 〈 5.6 mmol/L, n = 3738 ） and impaired fasting glucose group （ 5.6 mmol/L≤ FPG 〈 7.0 mmol/L,n = 136） according to their FPG levels. Results （ 1 ） After adjusting for age and sex using covariance analysis, the impaired fasting glucose group showed increased levels of body mass index, weight circumference, waist/hip ratio, waist/height ratio, as compared to the normal fasting glucose group （ P 〈 0. 05）. （2）After the age and gender were adjusted, body mass index, weight circumference, waist/hip ratio and waist/height ratio were positively correlated with FPG level （ P 〈 0.05 ）. Among the partial relation coefficients, that between waist/height ratio and FPG （r＇= 0. 0925 ） was the highest. （3） In multiple regression analyses, age （β = - 0.102, P 〈 0. 05 ）, family history of diabetes （β = 0. 186, P 〈 0. 05 ） and waist/height ratio （β = 0.842, P 〈 0.05 ） were consistently associated with FPG. Conclusion Central obesity was an important predictor of IFG in adolescents. Waist/height ratio may be an useful index of central obesity and an important predictor of IFG in adolescents.

关 键 词：糖尿病 超重 肥胖症 青少年 体脂分布 

分 类 号：R72[医药卫生—儿科]