非酒精性脂肪肝人群与行为因素的相关性研究  

Behavior factors associated with nonalcoholic fatty liver

作　　者：张毅[1] 王燕[1] 马先福[1] 王宏涛[1] 王仁萍[1] 

机构地区：[1]青岛大学医学院附属医院健康体检中心,266003

出　　处：《中华健康管理学杂志》2008年第5期284-287,共4页Chinese Journal of Health Management

摘　　要：目的通过对健康体检中非酒精性脂肪性肝病（NAFLD）人群与行为因素进行调查，研究其生活行为和疾病因素可能与NAFLD发病的相关性，并提出干预性防治措施。方法选择2038例健康体检者（包括1438例NAFLD患者）采用问卷调查的形式对其生活行为和疾病因素调查研究，并进行包括超声检查、肝功和血脂检测在内的常规体检，根据体检和问卷结果进行综合分析判断。结果多因素非条件Logistic回归分析结果表明：NAFLD患者男性20～49岁居多（76．5％）。工作压力大、睡眠过多、运动减少，高脂肪高蛋白饮食、喜好油煎炸、辛辣、甜食、冷饮、临睡前加餐等，体重指数和腰臀比值增加，伴随肥胖症、高血脂、高血压病、糖尿病、冠心病以及遗传和家族史等因素均与NAFLD的发病呈正相关（P〈0．05）。结论NAFLD的发病以男性青中年为主，且与多种生活行为和疾病因素密切相关，单纯性NAFLD是可逆性的，通过改变饮食结构、生活方式和控制原发基础疾病或伴随疾病等，可使NAFLD得到改善，甚至消失。Objective To study the behavior factors associated with nonalcoholic fatty liver disease （NAFLD）. Methods A total of 2038 subjects who underwent physical examination at the Department of Health check-up center, the Affiliated Hospital of Medical College, Qingdao University were included in this study（ including 1438 cases of NAFLD）. A questionnaire survey was conducted on their lifestyle and behaviors. Data of routine physical examination, ultrasound examination, liver function and blood lipid test were collected and analyzed. Results Multi-factors Logistic regression analysis showed that age （20 to 49 years） male sex, stress from work, sleep time, physical activity and diet are among factors associated with NAFLD （ all P 〈 0.05 ）. Condusion Lifestyle and behavior factors are associated with the incidence of NAFLD.

关 键 词：脂肪肝 体格检查 干预性研究 

分 类 号：R575[医药卫生—消化系统]