中药方剂与哈伯因对比治疗血管性痴呆患者的临床疗效观察  

Clinical effect observations on vascular dementia patients treated with Chinese medicinal formulae or Huperzine A

作　　者：施荣康 王玲琳 蔡新荣 SHI Rongkang , WANG Linglin , CAI Xinrong（ Cheng Qiao Community Health Service Center, Chang Ning District. Shanghai 201103, China）

机构地区：[1]上海市长宁区程桥社区卫生服务中心,201103

出　　处：《社区卫生保健》2008年第5期324-326,332,共4页Journal of Community Healthcare

摘　　要：目的探讨温阳补气祛瘀方治疗血管性痴呆（VD）的临床疗效。方法选取VD患者100例，随机分成试验组和对照组，每组50例。试验组给予服温阳补气祛瘀方煎剂治疗；对照组口服哈伯因片治疗。疗程均为半年。观察临床疗效及MMSE、HDS、FAQ量表得分情况。结果试验组总有效率68．0％，对照组总有效率54．0％。两组治疗前、后MMSE、HDS、FAQ量表得分比较差异均有统计学意义（P〈0．05）；试验组治疗后MMSE、HDS量表得分与对照组治疗后相比，差异具有统计学意义（P〈0．05）。且药物副作用试验组明显少于对照组。结论温阳补气祛瘀方治疗VD有肯定疗效。Objective To probe into the clinical effect of warming yang and benefiting qi for removing blood stasis decoction in treatment of vascular dementia（VD）. Method 100 cases of VD were randomly divided into testing group and control group with 50 cases each group. The patients in testing group treated with warming yang and benefiting qi for removing blood stasis decoction and control group with Huperzine A. Course of treatment is half a year. To observe the clinical effect and score of measuring scale MMSE, HDS and FAQ. Results Total effective rate of testing group is 68.0% and it of control group is 54.0%. Difference of score of measuring scale MMSE, HDS and FAQ of two groups between before and after treatment had statistical significance （P〈 0.05） ;Difference of score of measuring scale MMSE, HDS after treatment between two groups had statistical significance（P〈0.05）. Drug side effect of testing group is less than it of control group. Conclusion Warming yang and benefiting qi for removing blood stasis decoction has positive curative effect.

关 键 词：温阳补气祛瘀方 血管性痴呆 临床试验 中医药疗法 

分 类 号：R749.13[医药卫生—神经病学与精神病学;医药卫生—临床医学] R512.105[医药卫生—临床医学;医药卫生—内科学]