癌症患者生命质量测定量表体系之胃癌量表QLICP-ST的研制  

Development of the System of Quality of Life Instruments for Cancer Patients:Stomach Cancer(QLICP-ST)

作　　者：孟琼[1] 万崇华[1] 罗家洪[1] 汤学良[2] 李云峰[2] 寸英丽[2] 代佑果[2] 

机构地区：[1]昆明医学院公共卫生学院,云南昆明650031 [2]云南省肿瘤医院,云南昆明650031

出　　处：《癌症》2008年第11期1212-1216,共5页Chinese Journal of Cancer

基　　金：云南省自然科学基金(No.99C0016G)~~

摘　　要：背景与目的:有关癌症患者生命质量测定量表体系共性模块(quality of life instruments for cancer patients-general module,QLICP-GM)的研制已有报道。本研究在此基础上研制癌症患者生命质量测定量表体系之胃癌量表(quality of life instruments for cancer patients-stomach cancer,QLICP-ST),并对其进行评价。方法:采用量表开发的程序化方法研制量表,并应用该量表对86例胃癌患者进行生命质量测评。用内部一致性系数、相关分析、配对t检验和探索性因子分析等对量表的信度、效度和反应度进行考评。结果:总量表重测相关系数为0.98,各领域的重测相关系数均大于0.90。各个领域的内部一致性系数α在0.65以上,总量表的内部一致性系数α为0.91。相关分析与探索性因子分析结果显示量表的结构效度较好。躯体功能领域、心理功能领域、共性症状与副作用领域、特异模块以及总量表治疗前后的生命质量得分差异均有统计学意义(P<0.05)。而且,这些领域的标准化反应均数(standardized response mean,SRM)均在0.30以上。结论:QLICP-ST有较好的信度、效度和反应度,可用于临床胃癌患者生命质量的测评。BACKGROUND ＆ OBJECTIVE. We have previously developed and reported the general module of the system of quality of life instruments for cancer patients （QLICP-GM）. This study was to develop and evaluate the quality of life instrument for patients with stomach cancer （QLICP-ST）. METHODS： The QLICP-ST was developed using the structured group methods applicable to Chinese populations. The system of QLICP-ST was evaluated by analyzing data from 86 stomach cancer patients using statistical description, Pearson＇s correlation, exploratory factor analysis, and paired student＇s t test. RESULTS： The test-retest reliability of the overall scale was 0.98 and that of each domain was greater than 0.90. The internal consistency coefficient α of the overall scale was 0.91 and that of each domain was higher than 0.65. Correlation analysis and the exploratory factor analysis revealed good construct validity of the QLICP-ST. Differences of the quality of life scores before and after the treatment in physical domain, psychological domain, common symptom and side effect domain, specific domain and the overall scale were significant. Moreover, the standardized response mean （SRM） of these domains were greater than 0.30. CONCLUSION： The system of QLICP-ST can be used in clinical evaluation of the quality of life for stomach cancer patients with sound validity, reliability and responsiveness.

关 键 词：胃肿瘤 生命质量 量表 评价 

分 类 号：R735.2[医药卫生—肿瘤]