小儿血管网状细胞瘤术后残留的伽玛刀治疗  

Gamma knife radiosurgery for residual tumors after surgical resection of hemangioblastoma in children

作　　者：吕务军[1] 关健伟[1] 占克斌[1] 樊伟强[1] 李刚[1] 吴耀晨[1] 

机构地区：[1]深圳市第五人民医院脑病中心,518001

出　　处：《中华神经医学杂志》2008年第11期1166-1167,共2页Chinese Journal of Neuromedicine

摘　　要：目的探讨伽玛刀对小儿血管网状细胞瘤术后残留的治疗作用。方法回顾性分析9例小儿血管网状细胞瘤术后残留行伽玛刀治疗的临床资料，其中等剂量曲线范同平均50％，周边剂量平均18Gy，肿瘤中心剂量平均36．5Gy。结果9例患儿随访时间12－48个月，6例患儿肿瘤缩小50％以上，临床症状和体征得到明显改善；1例患儿无变化并再次行伽玛刀治疗；2例患儿肿瘤进行性增大．其中1例第二次伽玛刀治疗，1例第二次行开颅手术治疗。结论伽玛刀对小儿血管网状细胞瘤术后残留的治疗是一种安全、有效的方法，但要严格掌握适应证。Objective To assess the therapeutic effect of gamma knife radiosurgery for residual tumors after surgical resection of hemangioblastoma in children. Methods The clinical data were retrospectively analyzed in 9 children who received gamma knife radiosurgery for the residual tumors after a previous surgery for hemangioblastoma resection. Results The 9 children were followed up for 12-48 months, and 6 children showed a tumor volume reduction by over 50% with obviously improved clinical symptoms. One child showed no response to the treatment and received a second gamma knife radiosurgery. In 2 children, the tumor volume increased progressively after the radiosurgery, and a second radiosurgery was performed in 1 case and open surgery in the other. Conclusion Gamma knife radiosurgery is safe and effective for treatment of the residual tumors in children with previous surgical resection of hemangioblastoma.

关 键 词：伽玛刀 血管网状细胞瘤 儿童 

分 类 号：R73[医药卫生—肿瘤]