左旋多巴对弱视眼视诱发电位影响的研究  

Effect of Levodopa on Visual Evoked Potential in Amblyopia

作　　者：邓大明[1] 龙时先[1] 麦光焕[1] 吴德正[1] 陈国策[1] 

机构地区：[1]中山医科大学中山眼科中心,广州510060

出　　处：《眼科学报》1997年第4期182-185,共4页Eye Science

摘　　要：目的:探讨左旋多巴治疗弱视的效果。方法:正常眼和弱视眼服用单次剂量左旋多巴前后进行图形视诱发电位(pattem visual evoked poten-tial,PVEP)检测。结果:正常眼服药后中空间频率PVEP的N_1P_1振幅和高空间频率PVEP的P_1N_2振幅增大,弱视眼服药后低空间频率PVEP的N_1波潜伏期和中空间频率PVEP的P_1波潜伏期缩短。结论:左旋多巴可改善弱视眼的视功能,可作为弱视的一种新的治疗方法。眼科学报1997;13:182—185。Purpose :To evaluate the efficacy of levodpa treatment for amblyopia. Methods :The patients with amblyopin were given a single dose of levodopa, and the normal control group was established with the other normal eye in unilateral amblyopia. Their pattern visual evoked potential(PVEP) were tested before and after taking levodopa. Results:After taking a single dose of levodopa, the PVEP in the normal eyes showed that the N1P1 amplitudes evoked by middle spatial frequency stimuli and the P1N2 amplitudes e-voked by high spatial frequency stimuli increased, however, in the amblyopic eyes showed that the NI latency evoked by low spatial frequency stimuli and PI latency evoked by middle spatial frequency decreased. Conclusion:A single dose of levodopa administration can induce improvement of PVEP in the amblyopic eyes, and levodopa may be efficacious in the amblyopic therapy. Eye Science 1997;13:182-185.

关 键 词：弱视 药物 视诱发电位 左旋多巴 治疗 

分 类 号：R777.44[医药卫生—眼科]