肾脏病理改变与中医辨证关系的回顾性研究  

Retrospective Research in Correlation between Renal Pathology and Chinese Medicine Syndrome

作　　者：黎创[1] 谢羿[1] 

机构地区：[1]广州中医药大学第二临床医学院,2007级博士班广东广州510405

出　　处：《辽宁中医杂志》2008年第11期1619-1621,共3页Liaoning Journal of Traditional Chinese Medicine

摘　　要：目的:观察原发性肾小球疾病肾脏病理改变与中医辨证的关系。方法:对在广东省中医院进行肾穿活检,诊断为原发性肾小球疾病病历共144例进行病理与中医辨证的相关分析。结果:脾肾阳虚组病理表现最严重;气阴两虚组硬化较脾肾阳虚组轻但总体病变重于脾肾气虚组;兼见湿热内蕴证肾病理变化常见炎症浸润及组织增生,其程度较水湿内阻证明显;瘀血内阻型的肾组织增生及病理活动性均较水湿浸渍证明显;兼证中湿热内蕴证患者肾病理出现浸润的情况最为常见,瘀血内阻证的病理活动性最强。结论:原发性肾小球疾病在"脾肾气虚→气阴两虚(→肝肾阴虚)→脾肾阳虚"的转化过程中,病理浸润与硬化程度越来越严重。不同的证型之间肾病理改变程度存在显著性差异。Objective ： Studying the correlation between renal pathology and Chinese Medicine Syndrome. Methods ： General status,clinical information,pathological parameters,diagnoses were observed in 144 cases of primary glomerulus diseases. Results： The TCM Syndrome types are significantly correlated with the severity of their renal pathological changes ： Semi-quantitative scoring upon pathological changes showed that the total, sclerosis and activity scores were significantly higher in patients with deficiency of yang of spleen - kidney syndrome （ type 3） than in those with deficiency of qi of spleen - kidney syndrome （ type 1 ） ; The total,soakage,hyperplasia and activity scores were higher in patients with deficiency of both qi and yin syndrome （type 4） than in type 1. Conclusion ： Retrospective research proved that the TCM Syndrome type of patients with renal disease is significantly correlated with the severity of their renal pathological changes,thus,the TCM Syndrom shows definite referential importance to conclude the severity of renal pathological change in patients with renal disease.

关 键 词：原发性肾小球疾病 肾脏病理 中医证型 正虚 

分 类 号：R228[医药卫生—中医基础理论]