板层角膜移植术治疗带状角膜病变的临床研究  

Clinical research in the treatment of band-shaped keratopathy by lamellar keratoplasty

作　　者：李保江[1] 高晓唯[1] 李文静[1] 李霞[1] 任兵[1] 高云仙[1] 田艳明[1] 周昕[1] 闫海英[1] 杨磊[1] 

机构地区：[1]解放军第474医院眼科全军眼科中心

出　　处：《国际眼科杂志》2008年第11期2326-2327,共2页International Eye Science

摘　　要：目的:探讨板层角膜移植术对带状角膜病变的治疗效果。方法:2003-01/2008-01我院角膜病组收治带状角膜病变患者16例(16眼)。其中男12例(12眼),女4例(4眼),年龄20～55岁,病史3～20a,患眼视力为光感～0.1不等。手术方法:根据病变的范围,选择不同直径环钻切除病灶,10-0的尼龙线间断缝合等大的植片和植床。结果:术后1wk内,植片可轻度水肿,之后渐变清亮,术后观察6mo～5a,未见病变复发及发生排斥反应者。术后视力均有明显提高,术后6mo,视力≥0.5者3眼,0.1～0.5者11眼,指数～0.1者2眼。结论:板层角膜移植术可以控制带状角膜病变病情发展,提高患眼视力,远期疗效稳定,是治疗带状角膜病变安全有效的疗法。AIM： To investigate the treatment effect of lamellar keratoplasty on band-shaped keratopathy. METHODS： Sixteen cases （16 eyes） between January 2003 to January 2008, in which 12 cases （12 eyes） were male and 4 cases （4 eyes） were female, aged from 20 to 55 years old, were included. The time of the disease was between 3 and 20 years. The visual acuity was between light perception and 0. 1. According to the range of the disease, an annular-shaped ectatic lesion was defined and removed, and donor tissue of the same size and shape was sutured on the recipient bed with 10- 0 nylon. RESULTS： There was a little edema in cornea in one week, and then became clarity. No rejections and complications occurred between 6 months and 5 years of follow up. The visual acuity improved obviously. After lamellar keratoplasty 6 months, the visual acuity was 〉 0.5 in 3 eyes, 0.1-0.5 in 11 eyes, and 〈0.1 in 2 eyes. CONCLUSION： We have developed a safe, successful, and simple procedure for repairing the severe peripheral marginal ectasia in band-shaped keratopathy. This technique substantially improved visual acuity.

关 键 词：带状角膜病变 板层角膜移植 临床研究 治疗方法 

分 类 号：R779.65[医药卫生—眼科] R772.2[医药卫生—临床医学]