三维放射治疗计划系统临床物理数据的测量和验证  

Measurement and Verification of Clinical Physical Data in 3D TPS

作　　者：刘均[1] 陈宏[1] 王永刚[1] 刘凌[2] 任洪荣[2] 李英华[1] 

机构地区：[1]成都军区昆明总医院肿瘤科,云南昆明650032 [2]东南大学肿瘤研究所,江苏徐州210096

出　　处：《中国医学物理学杂志》2008年第6期875-879,共5页Chinese Journal of Medical Physics

摘　　要：目的:探讨三维治疗计划系统测量的方法,分析拟合数据参数的计算方法,并且利用测量设备验证计算数据和拟合参数的准确性。方法:利用PTW和IBA三维水箱模体对多套三维计划系统进行所需的临床物理数据进行测量,对一种治疗计划系统依据测量数据进行拟合公式得到的线性系数进行分析,得到治疗计划时所需的计算数据,并且利用测量设备对计算数据进行验证。结果:利用测试数据得到的拟合数据及计算模型相关系数输入到TPS后得到相应的计算数据。通过测试设备验证:拟合数据PDD与测量PDD一致性比较好,误差小于±1%;Profiles数据在半影区域,小射野一致性误差最大可达到3%。对TPS的数据验证,单野PDD剂量点和Profiles数据点均能在±3%以内。结论:了解三维治疗计划系统的计算模型和参与物理数据的测试对TPS的质量保证和质量控制具有积极意义。Objective： To study the measurement method of clinical physical data and to verify the accuracy of dose calculation and the precise of beam modeling in three dimension treatment-planning system. Methods： Based on measurement data, such as percentage depth dose （PDD）, out factors （Sc, Sp）, beam profiles and other data including of X-ray and electron ray, calculation beam model was set out; calculation data and measurement data were verified. By adjusting algorithms parameters to match beam model, we obtain calculation data. Results： The calculated pentage depth dose agreed with the easements within ±1%（ofthe dose maximum along the beam axis）, and the beam profiles agreed with the measurements within ±3%（or ±2mm in the penumbra region and high dose gradient region）. Conclusions： To obtain better and effective treatment planning system, the precise measurement data and accurate algorithms model must be set out completely. Those enable us to provide more detailed beam characteristics for beam fields than a measurement method, and which can provide better quality assure and quality control.

关 键 词：治疗计划 测量 验证 调强放射治疗 

分 类 号：R730.55[医药卫生—肿瘤] R814.2[医药卫生—临床医学]