磁场对糖尿病大鼠血清中铁相关蛋白的影响  

作　　者：毕得[1] 张小云[1] 苏湘鄂[1] 张宇[1] 

机构地区：[1]深圳大学生命科学学院,518060

出　　处：《当代医学》2008年第11期63-64,共2页Contemporary Medicine

摘　　要：目的观察旋转恒定磁场对大鼠血清中铁代谢相关蛋白的影响，为深入认识磁场的多方面生物学效应提供依据。方法将SD大鼠随机分为对照组和曝磁组。后者磁场强度是0．4T、频率为897Hz，每天曝磁1次，每次2h，连续处理30d后处死分组大鼠，获得血清，冻存后测定血清中铁蛋白和乳铁蛋白含量。结果曝磁组大鼠铁蛋白含量有显著性的降低（“p〈0.05”），乳铁蛋白含量有显著性的降低（“P〈0.01”）。结论磁场对大鼠血清中铁蛋白和乳铁蛋白存在影响。Objective The study was to observe the effects of rotating and stationary magnetic fields （RSMF） on serum iron metabolism-related protein in diabetes rat, and provide more correlated proof for having a better understanding of the biology effects of magnetic field. Methods The diabetes rats were randomly divided into a control group and a RSMF-treated group. The RSMF-treated group was exposed to RSMF for 2 hours a time, once a day during 30 consecutive days, and the magnetic intensity was 0.4T, the frequency was 4 Hz. Killed the rats after 30 days, got the blood of the rats, froze and save it.Detected the Ferritin content, and Lactoferrin（LF） content. Results There was not a significant change of Cp activity between RSMF group and control group, T-AOC in RSMF group was obviously lower than that from the control group（ P〈0.05）; Ferritin content was significantly lower in RSMF group （P〈0.05） ; and LF content increased significantly in RSMF group（ P〈0.05）.Conclusion The RSMF has effect to Ferritin and Lactoferrin in serum of diabetes rat.

关 键 词：旋转恒定磁场 糖尿病 铁代谢 铁蛋白 乳铁蛋白 

分 类 号：R587.1[医药卫生—内分泌]