消化道肿瘤肝转移介入治疗的临床应用及预后分析  

Prognostic analysis of interventional therapy for patients with liver metastases from alimentary tract malignancy

作　　者：李双生[1] 吕维富[1] 张正峰[1] 张行明[1] 肖景坤[1] 王伟昱[1] 张爱武[1] 谢亚敏[1] 

机构地区：[1]安徽医科大学附属省立医院影像科,安徽省合肥市230001

出　　处：《实用肝脏病杂志》2008年第6期388-390,共3页Journal of Practical Hepatology

基　　金：安徽省高校省级自然科学研究计划重点项目;编号:KJ2008A33ZC

摘　　要：目的探讨介入治疗消化道肿瘤肝转移的治疗疗效。方法回顾性分析96例胃癌、结肠癌和胰腺癌肝转移患者的介入治疗,随访7个月～5年,评价其治疗效果和生存率。结果29例胃癌肝转移患者平均生存期为22.7个月,1年、3年、5年生存率分别为93.1%、31.4%、13.8%;55例结肠癌肝转移患者平均生存期为19.4个月,1年、3年、5年生存率分别为85.5%、34.5%、10.9%;12例胰腺癌肝转移患者平均生存期为13.2个月,1年、3年生存率分别为57.1%、14.2%;本组患者总的平均生存期为17.8个月,1年、3年、5年生存率分别为85.4%、33.3%、10.4%。结论介入治疗是不能根治性切除的肝转移瘤患者的有效治疗方法,鳞癌、胰腺癌肝转移的患者预后较差,而富血供肿瘤、原发肿瘤已切除的患者预后较好、生存期较长。Objective To investigate the efficacy of interventional therapy for patients with liver metastases from alimentary tract malignancy. Methods 96 patients with liver metastases from alimentary tract malignancy received interventional therapy,and were followed-up for 7 months to 5 years. Results The mean survival time of patients with liver metastases from gastric,colon and pancreatic cancer were 22.7 months, 19.4 months and 13.2 months,respectively;and the 1-year, 3-year and 5-year survival rates in patinets from gastric cancer were 93.1% ,31.4% and 13.8% ,respectively,colon cancer were 85.5%,34.5% and 10.9%,respectively and 1-year and 3-year survival rates in patients from pancreatic can- cer were 57.1% and 14.2%,respectively. The CR plus PR in this series was 72.9% ,the mean survival time was 17.8 months,and the 1-year,3-year,5-year survival rates were 85.4%,34.4%,10.4%,respectively. Conclusion As a palliative treatment,the interventional therapy is effective for patients with liver metastasis from alimentary tract malignancy. The metastasis from squamous cell carcinoma or pancreatic carcinoma,or multiple metastasis lesions are poor prognostic factors,while metastatic leisions with complete resection of primary carcinoma and rich blood supply are good prognostic factors.

关 键 词：消化道肿瘤 肝转移瘤 介入治疗 预后 

分 类 号：R735[医药卫生—肿瘤]