氟比洛芬酯脂微球注射液对癌性疼痛控制的临床观察  

Analgesic Effect of Flurbiprofen Axetl Injection on Cancer Pain

作　　者：张毅[1] 吴一萍[1] 

机构地区：[1]皖南医学院第二附属医院肿瘤科,安徽芜湖241000

出　　处：《肿瘤基础与临床》2008年第6期531-532,共2页journal of basic and clinical oncology

摘　　要：目的观察氟比洛芬酯脂微球注射液对癌性疼痛的疗效和毒副反应。方法32例未使用强阿片类药物的癌性疼痛给予氟比洛芬酯脂微球注射液50～100mg／d静脉推注，应用1周以上，分别根据疗效以及毒副反应等进行评价。结果氟比洛芬酯脂微球注射液治疗癌性疼痛的有效率（CR＋PR）为56．25％，生活质量也得到不同程度的改善，毒副反应发生率低，程度轻，未见嗜睡、返酸、恶心呕吐、消化道出血、便秘、尿潴留及呼吸抑制等。结论氟比洛芬酯脂微球注射液治疗癌性疼痛效果理想，毒副反应少。Objective To observe the analgesic effect and adverse reactions of flurbiprofen axetl injection in the treatment of pain in cancer patients. Methods The study was conducted in 32 cases with cancer. Flurbiprofen axetl injection was given for at a dose ofS0-100 mg/d for 1 week. Results The overall effective rate （ CR ＋ PR） was 56.25% , severe adverse reactions of flurbiprofen axetl injection were not observed. Conclusion Flurbiprofen axetl injection was effective for cancer pain with little side effects.

关 键 词：氟比洛芬酯脂微球 癌性疼痛 镇痛作用 

分 类 号：R730.59[医药卫生—肿瘤]