手术联合辅助治疗对局部复发性直肠癌的疗效  

Retreatment for locally recurrent rectal cancer

作　　者：庄华章[1] 郭云[2] 唐宗江[2] 

机构地区：[1]海南省海口市人民医院肛肠外科,海口570208 [2]广西医科大学第一附属医院结直肠肛门外科,南宁530221

出　　处：《第三军医大学学报》2008年第24期2335-2337,共3页Journal of Third Military Medical University

摘　　要：目的探讨手术联合辅助治疗应用于局部复发性直肠癌的治疗效果。方法对1993年8月至2002年2月间收治的107例局部复发再治疗的患者不同治疗方法的疗效进行回顾性分析。结果手术联合辅助治疗(A组)32例,单纯手术(B组)37例,辅助治疗(C组)38例,3组中位年龄分别为:(49.3±20.7)、(44.4±25.4)、(52.9±29.1)岁。A、B、C组中位生存期分别为27.8、14.6、13.7个月。A组5年生存率显著优于B组和C组(P<0.05)。结论对于复发性直肠癌行包括积极的手术在内的综合治疗可以给患者带来长期生存的机会。Objective To explore the efficacy of various retreatment for locally recurrent rectal cancer after radical surgery. Methods Totally 107 patients of locally recurrent rectal cancer, who were admitted from August, 1993 to February, 2002 and retreated, were retrospectively analyzed. Results Thirty-two patients were treated by resection eombined with adjuvant therapy （group A）, 37 patients underwent resection alone （group B）, and 38 patients received adjuvant therapy alone （group C）. The medium age of these three groups was 49.3 ± 20.7, 44.4±25.4, 52.9±29.1, respectively. The median survival time of groups A, B, C was 27.8, 14.6, 13.7 months, respectively. The five-year survival rate of group A was significantly higher than that of groups B and C （P 〈 0. 05）. Conclusion The aggressive surgery combined with adjuvant therapy will improve the survival chance for the patients with locally recurrent rectal cancer after radical surgery.

关 键 词：直肠癌 局部复发 手术 辅助治疗 

分 类 号：R730.5[医药卫生—肿瘤] R735.31[医药卫生—临床医学]