7-羟基异黄酮衍生物的合成  

SYNTHESIZING THE DERIVATIVES OF 7-HYDROXYISOFLAVONE

作　　者：张银梅[1] 刘乐乐[2] 罗素琴[2] 

机构地区：[1]内蒙古自治区医院药剂处,内蒙古呼和浩特010017 [2]内蒙古医学院药学系

出　　处：《内蒙古医学院学报》2008年第5期348-350,共3页Acta Academiae Medicinae Neimongol

基　　金：内蒙古自然科学基金(200508010914)

摘　　要：目的:设计并合成7-羟基异黄酮的衍生物。方法:以苯乙酸、间苯二酚为原料,经傅克反应、环化、酰化、酯化反应制备目标化合物。结果与结论:所合成的4个化合物经IR、1H-NMR及元素分析确证结构,均未见文献报道。Objective： To design and synthesize the derivatives of 7 - hydroxyisoflavone. Methods： compounds were synthesized via 4 steps using phenylacetic acid and resorcinol as materials. Results and Conclusion：The chemical structures of target compounds were confirmed by IR, 1H -NMR and element analysis. The report about synthesizing the derivatives of 7 - hydroxyisoflavone was never found ago.

关 键 词：7-羟基异黄酮 合成 目标化合物 衍生物 

分 类 号：TQ46[化学工程—制药化工] R914.5[医药卫生—药物化学]