P物质、血管活性肠肽和神经肽Y在大鼠颌下腺分布与共存的免疫组织化学研究  

Immunohistochemical Study on the Distribution and Coexistence of SP, VIP and NPY in the Rat Submandibular Gland

作　　者：贾雪梅[1] 贾友苏[1] 王惠珠[1] 齐威琴[1] 侯思伟[2] 潘朝宠[2] 

机构地区：[1]安徽医科大学,合肥230032 [2]安徽中医学院针灸经络研究所

出　　处：《中国医学科学院学报》1997年第2期107-109,T001,共3页Acta Academiae Medicinae Sinicae

摘　　要：采用免疫组织化学ABC方法观察了P物质（SP）、血管活性肠肽（VIP）和神经肽Y（NPY）等神经肽在大鼠颌下腺内的分布和共存关系结果显示，颌下腺内有SP能、VIP能和NPY能神经支配，纤维呈串珠状或线状，主要走行于腺泡、导管和血管周围。颌下腺内副交感神经节细胞均呈SP、VIP和NPY免疫组化反应阳性。提示这些神经肽共存于神经节细胞内，可能参与调节颌下腺复杂的分泌活动和有效的血液供应。The distribution and coexistence of SP, VIP and NPY in the submandibur gland ofrat have been studied with immunohistochemical ABC methods- The results indicated thatSP、 VIP and NPY-IR nerve fibers were presented as varicose and linear profiIes, whichmainly travelled around acini' duct and blood vessels. The ganglion cells in submandibulargland showed SP、 VIP and NPY-IR all positive immunocytochemically. The findings indicat-ed that the neuropeptides were coexisted in the same neuron body and might play the role ofregulation of the secretary activity and effective blood supply.

关 键 词：P物质 血管活性肠肽 神经肽Y 颌下腺 

分 类 号：R322.5[医药卫生—人体解剖和组织胚胎学] R392.11[医药卫生—基础医学]