视网膜下液细胞学分析  

Cytological study of subretinal fluid

作　　者：许迅[1] 何志平[1] 

机构地区：[1]上海市第一人民医院眼科

出　　处：《中华眼科杂志》1997年第6期450-452,I028,共4页Chinese Journal of Ophthalmology

基　　金：上海市科学技术发展基金;香港眼科慈善基金

摘　　要：目的探讨视网膜下液中的细胞组成以及增殖性玻璃体视网膜病变（ｐｒｏｌｉｆｅｒａｔｉｖｅｖｉｔｒｅｏ－ｒｅｔｉｎｏｐａｔｈｙ，ＰＶＲ）中参与增殖的细胞的可能来源。方法采用自发荧光检查、免疫组织化学检查等方法对３５例视网膜下液进行细胞学检查。结果有大量视网膜色素上皮细胞（ｒｅｔｉｎａｌｐｉｇｍｅｎｔｅｐｉｔｈｅ－ｌｉｕｍ，ＲＰＥ）和少量来源于睫状上皮和虹膜的色素上皮细胞；还有数量不等的神经视网膜细胞和巨噬细胞。本组样品中未见Ｔ淋巴细胞和Ｂ淋巴细胞。结论ＲＰＥ、色素上皮细胞、神经视网膜细胞和巨噬细胞存在于视网膜下液中，并可能不同程度地参也了ＰＶＲ的形成和发展。Objectives To determine the cellular components of subretinal fluid and the origin of cells participating in the proliferation in the membranous tissue of proliferative vitreoretinopathy (PVR). Methods 35 subretinal fluid samples were studied by cytology using autofluorescent and immunohistochemical assays. Results There were a large quantity of retinal pigment epithelium (RPE) and small quantity of pigment epithelial cells originated from epithelial cells of ciliary body and iris, there were also various quantities of neuroretinal cells and macrophages. Neither Tlymphocytes nor Blymphocytes were found in this group of samples. Conclusions RPE, pigment epithelial cells, neuroretinal cells and macrophages are in subretinal fluid and may participate in the formation and development of PVR in various degrees.

关 键 词：视网膜脱离 细胞学 并发症 视网膜病变 PVR 

分 类 号：R774.13[医药卫生—眼科] R774.12[医药卫生—临床医学]