淋巴上皮样癌的光镜、电镜及免疫组织化学观察  

The histological, ultrastructural and immunohistochemical observations of lymphoepitheliomalike carcinoma(LELC)

作　　者：潘传敬[1] 刘宽宇 汪盛贤[1] 陈志远[1] 史晓东 

机构地区：[1]成都军区总医院病理科

出　　处：《临床与实验病理学杂志》1997年第4期323-325,I032,共4页Chinese Journal of Clinical and Experimental Pathology

摘　　要：目的：研究淋巴上皮样癌（ＬＥＬＣ）的本质特征。方法：光镜、电镜和免疫组化Ｃｙｔｏｋｅｒａｔｉｎ、ＥＭＡ、ＣＤ３、ＣＤ４５、ＣＤ２０观察６例ＬＥＬＣ癌细胞及浸润淋巴组织。结果：癌细胞含有张力微丝和桥粒样连接，Ｃｙｔｏｋｅｒａｔｉｎ阳性。浸润的淋巴细胞以Ｔ细胞为主，能直接破坏癌细胞。结论：ＬＥＬＣ是一种具有特殊组织学表现的低分化鳞癌。Purpose To study the essence of LELC. Methods Six cases of LELC were observed by LM, EM and immunohistochemical technique using cytokeratin, EMA, CD3, CD45, CD20. Results In the carcinoma cells there were tonofibrils and desmosomelike junctions, and cytokeratin positive staining. The infiltrated lymphocytes mainly was T cells and they could kill and destroy the carcinoma cells. Conclusions LELC is a rare poor differential squamous carcinoma possessing particular histological characterics.

关 键 词：淋巴上皮样癌 淋巴系肿瘤 免疫组织化学 

分 类 号：R733.102[医药卫生—肿瘤]