广东、海南二省HTLV-1感染的流行病学及其与疾病相关性的研究  

A Seroepidemiologic Survey: Antibodies to HTLV-Ⅰin sera from various populations in Guang Dong and Hai Nan

作　　者：杨棉华[1] 余秀葵[1] 庄坚[1] 郑璇[2] 庄春兰[2] 许立德[2] 黄立群[2] 

机构地区：[1]汕头大学医学院微生物学教研室 [2]汕头大学第一附属医院

出　　处：《汕头大学医学院学报》1997年第A00期25-27,共3页Journal of Shantou University Medical College

摘　　要：本文报道广东、海南二省人群HTLV－1感染的血清流行病学调查结果，并对其与某些疾病的关系作初步探讨。共收集广东省各类人群血清标本2369份，其中健康人群血清1810份，抗体阳性23份，阳性率为1．27％；献血员血清248份，阳性抗体1份，阳性率0．40％；成人白血病患者血清10份，阳性3份，阳性率7．34％，与健康人群比较，有非常显著的差异（P＜0．005）；儿童血液病患者血清33份，阳性2份，阳性享6．06％；神经系统疾病患者血清97份，阳性5份，阳性单5．15％；类风湿病患者血清72份，阳性2份，阳性率2．78％。海南省健康人群血清622份．抗体阳性13份，阳性率2．09％。The Seroepidemiologic survey of HTLV-Ⅰ infection in Guang Dong and Hai Nan provinces was reported here. 2369 and 622 serum samples from various population were collected respectively. The antibodies to HTLV-Ⅰ in sera were detected with indirect immunofluorescent assay. The antibody positive rates of HTLV-Ⅰ in sera from healthy individuals were 1.27% and 2.09% in Guang Dong (n = 1810) and in Hai Nan (n= 622). The seropositive antibodies for HTLV-Ⅰ also found in the patients with T cell leukemia (n = 109), patients with neurological diseases (n = 97) and rheumatoid patients (n = 72) were 7.34%, 5. 15% and 6.06%, respectively. There was significant difference between the patients with T cell leukemia and the healthy individuals (P <0.005).

关 键 词：嗜T细胞病毒 Ⅰ型 白血病 类风湿病 流行病学 

分 类 号：R373.9[医药卫生—病原生物学] R733.7[医药卫生—基础医学]