Regioselective Deprotection of 1,3-Dibenzyl-5-(N,N-dimethylamino)-6-phenylethyluracil  

作　　者：LI A-min WANG Xiao-wei ZHANG Zhi-li CHENG Zhi-jian LIU Jun-yi 

机构地区：[1]Department of Chemical Biology [2]State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100083, P R. China [3]Department of Chemistry, College of Jiujiang, Jiujiang 33200, P R. China

出　　处：《Chemical Research in Chinese Universities》2008年第6期735-738,共4页高等学校化学研究（英文版）

基　　金：Supported by the National Natural Science Foundation of China(No.20672008); "985" Program of the Ministry of Edu-cation of China

摘　　要：The deprotection of 1,3-dibenzyl-5-（N,N-dimethylamino）-6-phenyl-ethyluracil I was investigated. A practical, regioselective N3 deprotection of compound I was performed with excellent yield using cyclohexene as a hydrogen donor.The deprotection of 1,3-dibenzyl-5-（N,N-dimethylamino）-6-phenyl-ethyluracil I was investigated. A practical, regioselective N3 deprotection of compound I was performed with excellent yield using cyclohexene as a hydrogen donor.

关 键 词：1 3-Dibenzyl-5-（N N-dimethylamino）-6-phenylethyluracil Benzylprotecting DEPROTECTION 

分 类 号：O6[理学—化学]