DEPROTECTION

作品数:28被引量:9H指数:2
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相关领域:理学更多>>
相关作者:刘立辉代小娟余友清杨静莉夏德安更多>>
相关机构:东北林业大学北京师范大学中国科学院更多>>
相关期刊:《Chemical Research in Chinese Universities》《Chinese Journal of Chemical Engineering》《Science China Chemistry》《有机化学》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划更多>>
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Development of ESIPT-based specific fluorescent probes for bioactive species based on the protection-deprotection of the hydroxyl
《Chinese Chemical Letters》2025年第2期21-28,共8页Haixian Ren Yuting Du Xiaojing Yang Fangjun Huo Le Zhang Caixia Yin 
National Natural Science Foundation of China(Nos.22277104,22325703,22074084);the Natural Science Foundation of Shanxi Province(No.202203021212184);Research Project supported by Shanxi Scholarship Council of China(No.2022-002);the Basic Research Program of Shanxi Province(Free Exploration)(No.202203021221009);2022 Lvliang City science and technology plan project(Nos.2022SHFZ51,2022GXYF15);Scientific Instrument Center of Shanxi University(No.201512)。
Excited-state intramolecular proton-transfer(ESIPT)based fluorescence probes are particularly attractive due to their unique properties including environmental sensitivity,a large Stokes shift,and potential for ratiom...
关键词:ESIPT Protection-deprotection SPECIFICITY Fluorescence probe BIOIMAGING 
Rational design of nitrogen-doped carbon for palladium catalysts in hydrogenation of hydrazo compounds
《Chinese Journal of Chemical Engineering》2025年第1期156-166,共11页Junzhe Xu Shuang Liu Lin Li Xian Qin Ruixin Qu Jinguo Wang Di Liu Gaixia Wei 
supported by the National Natural Science Foundation of China(21503264,22179081 and 22076117);Natural Science Foundation of Shanghai(20ZR1422500).
We synthesized CN11,a carbon nitride material rich in sp^(3)hybrid graphitic nitrogen(sp^(3)-N),employing a facile oxalic acid-assisted melamine molecular assembly strategy.CN11 promoted the formation of Pd nanopartic...
关键词:Pd nanocatalyst Nitrogen-doped carbon HYDROGENATION Deprotection of CBz Bimethylation of amino 
A novel route for the synthesis of androgen receptor antagonist enzalutamide
《Chinese Chemical Letters》2023年第6期449-453,共5页Xiangguo Meng Siju Bi Shixin Jin Kai Wu Shanchao Wu Lei Shao Pierre-Antoine Bonnet Chunquan Sheng 
supported by Scientific Research Cadre Project(AMSCP)2021;National Key Research and Development Program of China(No.2020YFA0509200 to C.Sheng)。
A novel route of enzalutamide was developed in five steps.Starting from 4-amino-2-(trifluoromethyl)benzonitrile(7)and Boc-2-aminoisobutyric acid(16),condensation,deprotection,Ullmann coupling,cyclization and amination...
关键词:Enzalutamide CONDENSATION DEPROTECTION Ullmann coupling CYCLIZATION AMINATION 
The 3,4-dimethoxybenzyl group as solubilizing protective group for the in situ deprotection/deposition of extended aromatic thiolate monolayers
《Nano Research》2023年第1期1695-1702,共8页Adrian Wiesner Sonja Katzbach Dariusz Bebej Martina Dettenhöfer Michael Zharnikov Andreas Terfort 
While self-assembled monolayers(SAMs)of aromatic thiolates are frequently used in a wide range of applications,their formation is often hampered by the low solubilities of their precursors.Here we introduce the 3,4-di...
关键词:self-assembled monolayers protective group SOLUBILITY scanning-tunneling microscopy infrared-reflection absorption spectroscopy 
A Mild and Efficient Method for the Synthesis of Acylals from Aromatic Aldehydes and Their Deprotections Catalyzed by Synthetic Phosphates under Solvent-Free Conditions
《Green and Sustainable Chemistry》2018年第4期334-344,共11页Fathallaah Bazi Bahija Mounir Mohammed Hamza Said Sebti 
An efficient and clean preparation of acylals from aromatic aldehydes in the presence of synthetic phosphates (flourapatite and hydroxyapatite doped with ZnCl2 and ZnBr2) and acetic anhydride was achieved easily in hi...
关键词:SYNTHETIC PHOSPHATES Clean Process ACYLALS Protection DEPROTECTION 
Solvent-Free Mechanochemical Deprotection of N-Boc Group
《International Journal of Organic Chemistry》2017年第2期140-144,共5页Mateja Dud Davor Margetic 
The financial support of this work by the Croatian Science Foundation(grant No.9310)is acknowledged.
Boc protection group could be readily removed in a very mild mechanochemical conditions. In a short reaction time, ball milling of Boc-protected amines with p-toluenesulfonic acid in solvent-free conditions affords co...
关键词:Green Chemistry MECHANOSYNTHESIS Boc Deprotection 
A facile method for building fused quinoxaline-quinolinones via an acidless post-Ugi cascade reaction
《Chinese Chemical Letters》2017年第3期541-545,共5页Yong Li Jie Lei Jia Xu Dian-Yong Tang Zhong-Zhu Chen Jin Zhua Chuan Xu 
the Chongqing Research Program of Basic Research and Frontier Technology(Nos.cstc2015jcyj A1328 and cstc2015zdcy-ztzx0191);the Scientific Research Foundation of Chongqing University of Arts and Sciences(Nos.R2013XY01 and R2013XY02);Sichuan Provincial Science Fund for Distinguished Young Scholars(No.2015JQO055)
A series of quinolino[3,4-b]quinoxalin-6(5H)-ones have been synthesized using an Ugi/deprotection/cyclization(UDC) strategy, followed by a nucleophilic aromatic substitution reaction. This facile microwave-assiste...
关键词:Quinoxaline Quinolino[3 4-b]quinoxalin-6(5H)-one Ugi/deprotection/cyclization(UDC) strategy Nucleophilic substitution reaction One-pot 
Photochemical Reaction of Benzoin Caged Compound: Time-Resolved Fourier Transform Infrared Spectroscopy Study
《Chinese Journal of Chemical Physics》2016年第1期91-98,I0002,共9页代小娟 余友清 刘坤辉 苏红梅 
This work was supported by the National Natural Science Foundation of China (No.21333012 and No.21425313) and the National Basic Research Program of China (No.2013CB834602).
The benzoin group caged compound has received strong interests due to its excellent photo- deprotection properties and wide use in chemical and biological studies. We used timeresolved infrared spectroscopy to investi...
关键词:BENZOIN Caged compound Photo-deprotection Time-resolved infrared spectroscopy 
Deprotection chemistry-mediated protein activation in living cells
《Science Foundation in China》2015年第1期8-8,共1页
support from the National Natural Science Foundation of China
a research team led by Prof.Chen Peng at the College of Chemistry and Molecular Engineering(CCME),Peking University reported a chemical rescue strategy for restoring a specific protein’s function inside live cells.Th...
关键词:PEKING INTRACELLULAR modulate RESCUE Nature fashion ASCERTAIN EFFECTOR throughput palladium 
The synthesis, deprotection and properties of poly(γ-benzyl-L-glutamate)被引量:2
《Science China Chemistry》2013年第6期729-738,共10页HAN JinDong DING JianXun WANG ZhiChun YAN ShiFeng ZHUANG XiuLi CHEN XueSi YIN JingBo 
financially supported by the National Natural Science Foundation of China (50973060, 51173101, 51003055, 51233004, 51273196,50973108 and 51203153);the Science and Technology Commission of Shanghai Municipality (11JC1404200);the Innovation Program of Shanghai Municipal Education Commission (11YZ06)
Diethylamine, di-n-hexylamine, dicyclohexylamine and triethylamine have been used as initiators for the ring-opening polymerization of γ-benzyl-L-glutamate N-carboxyanhydride (BLG NCA) to synthesize poly(γ-benzyl...
关键词:BIOCOMPATIBILITY BIOMATERIALS DEPROTECTION poly(γ-benzyl.L-glutamate) polymerization 
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