supported by Shandong BellaGen Biotechnology Co.,Ltd.,and by grants from the National Natural Science Foundation of China(32188102 to J.-K.Z.and 32270050 to Ning J.);the Guangdong and Shenzhen Natural Science Foundation(2024A1515010541 and JCYJ20220530114409022 to Ning J.);the Guangdong Provincial Science and Technology Innovation Council Grant(2017B030301018).
Dear Editor,Class 2 type V CRISPR-Cas12 effectors exhibit tremendous diversity,utilizing either single crRNAs or dual RNA guides to target double-stranded DNA(dsDNA),single-stranded DNA(ssDNA)or RNA.For dsDNA targets,...
supported by the Rural & Environment Science & Analytical Services (RESAS) Division of the Scottish Government through project JHI-B1-1;the Biotechnology and Biological Sciences Research Council (BBSRC) through awards BB/ S015663/1;BB/X009068/1;Research Leaders 2025 fellowship funded by European Union’s Horizon 2020 research and innovation programme under Marie Sklodowska-Curie grant agreement no. 754380;the Research/Scientific Computing teams at The James Hutton Institute and NIAB for providing computational resources and technical support for the “UK’s Crop Diversity Bioinformatics HPC” (BBSRC grant BB/ S019669/1)。
An accurate assessment of host and pathogen gene expression during infection is critical for understanding the molecular aspects of host-pathogen interactions.Often,pathogen-derived transcripts are difficult to ascert...
funded by State Key Laboratory of North China Crop Improvement and Regulation(NCCIR2023ZZ-10);the National Natural Science Foundation of China(32172384 and 31501623);the Natural Science Foundation of Hebei(C2020204028);the Science and Technology Research Project of Higher Education of Hebei(ZC2023178).
The NAC(NAM,ATAF1/2,and CUC2)is a defense-associated transcription factor(TF)family that positively regulates defense responses to pathogen infection.TaNAC069 positively regulates resistance in wheat to Puccinia triti...
supported by the Key Laboratory of Plant Design,CAS Center for Excellence in Molecular Plant Sciences,Institute of Plant Physiology and Ecology,Chinese Academy of Sciences(Li Wan);National Natural Science Foundation of China 32270304(Li Wan);Chinese Academy of Sciences Strategic Priority Research Program Type-B XDB27040214(Li Wan)。
Insects secret chemosensory proteins(CSPs)into plant cells as potential effector proteins during feeding.The molecular mechanisms underlying how CSPs activate plant immunity remain largely unknown.We show that CSPs fr...
supported by the Open Fund of the Key Laboratory of Integrated Pest Management on Crop in Northwestern Oasis,Ministry of Agriculture and Rural Affairsof China(KFJJ202101);the National KeyR&D Program of China(2021YFD1400100);the National Natural Science Foundation of China(31972247);the Tianchi Talent Introduction Program in Xinjiang Uygur Autonomous Region,China and the Science and Technology Innovation Project of the Chinese Academy of Agricultural Sciences.
The sugar beet cyst nematode(Heterodera schachtii) is one of the most destructive pathogens in sugar beet production, which causes serious economic losses every year. Few molecular details of effectors of H. schachtii...
supported by the Hainan Provincial Natural Science Foundation of China(323MS102 and 320QN307);Central Public-Interest Scientific Institution Basal Research Fund,China(1630042022008)。
Meloidogyne spp.is an economically important plant-parasitic nematode distributed worldwide.To fight with host immune system for successful parasitism,plant parasitic nematodes secrete effectors to promote infection.I...
supported by grants from the Natural Science Foundation of China(32370322);the Hainan Excellent Talent Team,and the State Key Laboratory of Plant Genomics.
Many Gram-negative pathogens employ the type III secretion system(T3SS)to deliver effector proteins into host cells,thereby modulating host cellular processes and suppressing host immunity to facilitate pathogenesis a...
supported by grants from the National Key Research and Development Program of China(2022YFF1001500);the Fundamental Research Funds for the Central Universities(CGPY2024001);the Zhongshan Biological Breeding Laboratory(ZSBBL-KY2023-03)。
Soybean rust(SBR),caused by an obligate biotrophic pathogen Phakopsora pachyrhizi,is a devastating disease of soybean worldwide.However,the mechanisms underlying plant invasion by P.pachyrhizi are poorly understood,wh...
Tuberculosis caused by Mycobacterium(M.)tuberculosis remains a global public health threat.Over the last few decades,anti-tubercular research mainly focused on mechanisms of identifying by which activated macrophages ...
supported by grants from the Elite Young Scientists Program of the CAAS (110243160001008);the Program for Guangdong “Zhu Jiang” Introducing Innovative and Entrepreneurial Teams (2019ZT08N628);the Shenzhen Science and Technology Program (AGIS-ZDKY202002)。
Fusarium head blight(FHB), caused by Fusarium graminearum, is a devastating disease of wheat globally. However, the molecular mechanisms underlying the interactions between F. graminearum and wheat remain unclear. Her...