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Genetic basis of the mucilage secretion ability associated with nitrogen fixation from aerial roots of maize inbred lines under low nitrogen conditions: 《The Crop Journal》2025年第2期432-443,共12页Bowen Zhao Xin Hou Zhongliang Yu Ronghui Zhang Huixin Teng Ziqiong Yang Jianju He Huijuan Wang Zhihao Song Jiankang Zheng Bolin Song Shiwei Ma Doudou Sun Xiaowei Fan Jingyang Gao Zijian Zhou Jiafa Chen Pei Jing Jianyu Wu; supported by the National Natural Science Foundation of China(32401919);the Department of Science and Technology of Henan Province(242102111126).; Recent studies have shown that mucilage secretion from aerial roots is an essential feature of modern maize inbred lines,with some retaining the nitrogen-fixing capabilities of ancient landraces.To explore the genetic...; 关键词：Biological nitrogen fixation Maize aerial root Mucilage secretion ability Low nitrogen Candidate genes

Hepatic Surf4 Deficiency Impairs Serum Amyloid A1 Secretion and Attenuates Liver Fibrosis in Mice: 《Research》2025年第1期921-934,共14页Bingxiang Wang Huili Li Govind Gill Xiangyan Zhang Geru Tao Boyan Liu Lei Zhai Wei Chen Hao Wang Hong-Mei Gu Shucun Qin Da-Wei Zhang; supported by the National Natural Science Foundation of China(NSFC 81929002);a grant from the Canadian Institutes of Health Research(PS 178091);the Academic promotion program of Shandong First Medical University(2019QL010);the Natural Science Foundation of Shandong Province(ZR2021MH015);D.W.Z.was also supported by the Natural Sciences and Engineering Research Council of Canada(RGPIN-2016-06479);S.Q.was also supported by the Taishan Scholars Foundation of Shandong Province(ts201511057).; Liver fibrosis is a severe global health problem.However,no effective antifibrotic drugs have been approved.Surf4 is primarily located in the endoplasmic reticulum(ER)and mediates the transport of secreted proteins fr...; 关键词：golgi apparatusknockout proteomics collagen antifibrotic drugs serum amyloid liver fibrosis endoplasmic reticulum er

Continuum of glucose and bone metabolism impairment across autonomous cortisol secretion: A cross-sectional study: 《World Journal of Diabetes》2025年第3期134-145,共12页Min-Min Han Xiao-Ming Cao Zi-Ang Liu Yi Zhang Yun-Feng Liu; Supported by National Natural Science Foundation of China(General Program),No.82073909;Four‘Batches’Innovation Project of Invigorating Medical through Science and Technology of Shanxi Province,No.2023XM022;The Shanxi Provincial Central Leading Local Science and Technology Development Fund Project,No.YDZJSX2022A059 and No.YDZJSX20231A059。; BACKGROUND Autonomous cortisol secretion(ACS)is linked to a higher prevalence of metabolic abnormalities and an increased risk of major adverse cardiovascular events.AIM To evaluate glucose and bone metabolism in pati...; 关键词：Continuous glucose monitoring system Glucose variability Time in range Autonomous cortisol secretion Bone mineral content Bone mineral density Bone area

TMEM39A and TMEM131 facilitate bulk transport of ECM proteins through large COPII vesicle formation: 《Journal of Genetics and Genomics》2025年第2期189-203,共15页Jee Young Sung Ga-Eun Lim Jarim Goo Kyung Jin Jung Jeong Min Chung Hyun Suk Jung Yong-Nyun Kim Jaegal Shim; supported by the National Institutes of Health-Office of Research Infrastructure Programs(P40 OD010440);supported in part by grants from the National Cancer Center of Korea(NCC-2110160,NCC-2110263,and NCC-2310750);supported by the Basic Science Research Program of the National Research Foundation of Korea,funded by the Ministry of Science,ICT,and Future Planning(NRF-2015R1C1A1A01053611).; The growth of Caenorhabditis elegans involves multiple molting processes,during which old cuticles are shed and new cuticles are rapidly formed.This process requires the regulated bulk secretion of cuticle components....; 关键词：Bulk secretion COLLAGEN COPII ECM TMEM39A TMEM131

Known and unknown:Exosome secretion in tumor microenvironment needs more exploration: 《Genes & Diseases》2025年第1期158-171,共14页Mengxiang Huang Jie Ji Xuebing Xu Dandan Jin Tong Wu Renjie Lin Yuxuan Huang Jiawen Qian Zhonghua Tan Feng Jiang Xiaogang Hu Weisong Xu Mingbing Xiao; supported by grants from the National Natural Science Foundation of China(No.82272624);the Natural Science Foundation of Jiangsu Province,China(No.BK20211105);the Plan of Jiangsu Provincial Medical Key Discipline(China)(No.ZDXK202240);the Social Development Foundation of Nantong City,Jiangsu,China(No.MS22022044,JC22022001,JCZ2022027);the Health Project of Nantong City,Jiangsu,China(No.MS2022056);the Postgraduate Research and Practice Innovation Program of Jiangsu Province,China(No.SJCX21_1452,KYCX21_3112,KYCX23_3419);Jiangsu Provincial Research Hospital(China)(YJXYY202204);the Jiangsu Administration of Traditional Chinese Medicine(China)(JD2022SZ07);Teaching Research Project of Affiliated Hospital of Nantong University(China)(Tfj22002).; Exosomes,extracellular vesicles originating from endosomes,were discovered in the late 1980s and their function in intercellular communication has since garnered considerable interest.Exosomes are lipid bilayer-coated...; 关键词：Exosome cargo Exosome secretion Intercellular communication TUMOR Tumor microenvironment

Bifidobacterium longum subsp.infantis CCFM1269 promotes intestinal barrier and release of IFN-β through TLR4-TRIF dependent way in growing mice: 《Food Science and Human Wellness》2025年第1期345-360,共16页Mengfan Ding Bo Yang Bowen Li Haiqin Chen Renqiang Yu RPaul Ross Catherine Stanton Shilong Jiang Jianxin Zhao Wei Chen; funded by the National Key R&D Program of China(2021YFD2100700);National Natural Science Foundation of China(32021005);111 project(BP0719028);Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province。; Bifidobacterium longum subsp.infantis is a commensal bacterium that predominates in the infant gut,playing a critical role in both preventing foreign infections and facilitating immune development.This study aimed to ...; 关键词：Bifidobacterium longum subsp.infantis Intestinal barrier interferon-beta(IFN-β)secretion Age dependence

IL2-mediated modulation of small extracellular vesicles secretion and PD-L1 expression: a novel perspective for neutralizing immune suppression within cancer cells: 《Cancer Communications》2024年第12期1422-1426,共5页Soojeong Noh Suyeon Ryu Dokyung Jung Sanghee Shin Inseong Jung Sung-Min Kang Christine Seulki Kim Sung-Jin Choi Hanchae Cho Melanie Schwammle Youngtae Jeong Felicitas Bucher Il-Kyu Choi Shin Yup Lee Sin-Hyeog Im Kyungmoo Yea Moon-Chang Baek; supported by the Bio&Medical Technology Development Program of the National Research Foundation(NRF)of Korea funded by the Korean government(MSIT)(2022R1A2C109214511 and 2020M3A9I4039539);the National Research Foundation of Korea(NRF)grant funded by the Korean government(MSIT)(2021R1A5A2021614,2023R1A2C3005553);the DGIST Program of the Ministry of Science and ICT(21-DGRIP-01).; Cancer cells secrete small extracellular vesicles(sEVs)to regulate various cellular functions,like tumor growth and metastasis,by promoting epithelial-mesenchymal transition and angiogenesis[1,2].Additionally,cancer c...; 关键词：PDL1 CANCER CANCER

self-assembling split Nano luciferase-based assay for investigating Pseudomonas syringae effector secretion: 《Stress Biology》2024年第1期594-599,共6页Pei Miao Jian-Min Zhou Wei Wang; supported by grants from the Natural Science Foundation of China(32370322);the Hainan Excellent Talent Team,and the State Key Laboratory of Plant Genomics.; Many Gram-negative pathogens employ the type III secretion system(T3SS)to deliver effector proteins into host cells,thereby modulating host cellular processes and suppressing host immunity to facilitate pathogenesis a...; 关键词：Pseudomonas syringae T3SS effectors SECRETION Nano luciferase

Phospholipase PlcH is involved in the secretion of cell wall glycoproteins and contributes to the host immune response of Aspergillus fumigatus: 《mLife》2024年第4期537-550,共14页Jinbin Hao Yin Guo Hui Zhou Haomiao Ouyang Jinghua Yang Wenxia Fang Cheng Jin; supported by the National Key Research and Development Program of China(2021YFC2300400);the National Natural Science Foundation of China(32371337).; Glycosylphosphatidylinositol(GPI)anchoring is one of the conserved posttranslational modifications in eukaryotes that attach proteins to the plasma membrane.In fungi,in addition to plasma membrane GPI‐anchored protei...; 关键词：Aspergillus fumigatus cell wall protein GPI‐anchored protein immune response macrophage killing

Seasonal variation of melatonin secretion across various segments of the gastrointestinal tract in rats: 《Journal of Traditional Chinese Medical Sciences》2024年第3期275-282,共8页Yuxin Zhang Xuejie Huang Yilu Peng Yuxi Liang Wenjing Zhang Yadong Cui Xiaoying Xu Xiuhua Hu Xiaoyan Liu; supported by the National Natural Science Foundation of China(81001482 and 81973716).; Objective:To investigate whether melatonin(MT)secretion in different parts of the gastrointestinal tract(GIT)exhibits seasonal variations and its correlation with immune regulation.Methods: Sixty Sprague-Dawley rats w...; 关键词：MELATONIN Seasonal variations Pineal gland Gastrointestinal tract Melatonin receptors

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