MELATONIN

作品数:429被引量:1205H指数:15
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相关领域:医药卫生更多>>
相关作者:付良青骆传环舒融孙凤艳李学君更多>>
相关机构:军事医学科学院解放军第307医院中国农业大学华中科技大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划安徽省自然科学基金中国博士后科学基金更多>>
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Aging-induced memory loss due to decreased N1-acetyl-5-methoxykynuramine,a melatonin metabolite,in the hippocampus:a potential prophylactic agent for dementia被引量:1
《Neural Regeneration Research》2025年第6期1705-1706,共2页Kazuki Watanabe Atsuhiko Hattori 
supported by JSPS KAKENHI Grant Number JP22K11823 to AH and JP22J01508 to KW。
Melatonin(N-acetyl-5-methoxytryptamine)is known as the hormone of darkness because it is synthesized at night and involved in regulating the circadian clock.The hormone is primarily synthesized by the vertebrate pinea...
关键词:metabolism primarily AGENT 
Melatonin improves endometrial receptivity and embryo implantation via MT2/PI3K/LIF signaling pathway in sows
《Journal of Animal Science and Biotechnology》2025年第2期631-652,共22页Xue Qin Menghao Yang Yang Yu Xiaolin Wang Yi Zheng Rui Cai Weijun Pang 
supported by the China Agriculture Research System(CARS-35-PIG);the National Natural Science Foundation of China(32272847,U22A20516);the National Key Research and Development Program of China(No.2021YFF1000602);the Key Research and Development Program of Shaanxi Province(No.2022ZDLNY01–04)。
Background Increased backfat thickness of sows in early gestation is negative to reproductive performance.Endometrial receptivity is an important determinant of reproductive success,but it is unclear whether the effec...
关键词:Backfat thickness Embryo implantation Endometrial receptivity MELATONIN MT2/PI3K/LIF SOW 
The protective effects of melatonin against electromagnetic waves of cell phones in animal models:A systematic review
《Animal Models and Experimental Medicine》2025年第4期629-637,共9页Mohammad Amiri Habibolah Khazaie Masoud Mohammadi 
Deputy for Research and Technology,Kermanshah University of Medical Sciences,Grant/Award Number:4030031。
Background:Due to the widespread use of cell phone devices today,numerous re-search studies have focused on the adverse effects of electromagnetic radiation on human neuropsychological and reproductive systems.In most...
关键词:animal model cell phone radiation MELATONIN 
Antioxidant Protective Effect of Melatonin on Cyclophosphamide-Induced Premature Ovarian Failure and its Mechanism
《Proceedings of Anticancer Research》2025年第2期56-70,共15页Chongran Liu Tongtong Wei Xinyue Rao Ziqi Fan Minghui Hao Wanjing Wang Yihang Song 
2023 Special Project for Serving the National Development Strategy with Basic Scientific Research Fees from Central Universities(No.31920230188);2023 Northwestern Minzu University College-Level Innovation and Entrepreneurship Training Program(No.X202310742289);2024 National College Students’Innovation and Entrepreneurship Training Program(No.202410742005)。
Objective:To study the antioxidant protective effect and mechanism of melatonin on cyclophosphamide-induced premature ovarian failure model mice.Methods:Six-month sexually mature female Kunming mice were taken for one...
关键词:MELATONIN CYCLOPHOSPHAMIDE Premature ovarian failure ANTIOXIDATION 
Melatonin ameliorates Slc26a2-associated chondrodysplasias by attenuating endoplasmic reticulum stress and apoptosis of chondrocytes
《Genes & Diseases》2025年第2期425-437,共13页Pan Li Chao Zheng Jingyan Hu Weiguang Lu Dong Wang Xue Hao Chengxiang Zhao Liu Yang Zhuojing Luo Qiang Jie 
supported by the National Natural Science Foundation of China (No.82272442,82372361);the Key Industrial Chain Program of Shaanxi,China (No.2022ZDLSF02-12).
Although the pathogenesis and mechanism of congenital skeletal dysplasia are bet-ter understood,progress in drug development and intervention research remains limited.Here we report that melatonin treatment elicits a ...
关键词:Ca^(2+)overload CHONDRODYSPLASIA Endoplasmic reticulum stress MELATONIN SLC26A2 
Melatonin Mitigates Atrazine-Induced Renal Tubular Epithelial Cell Senescence by Promoting Parkin-Mediated Mitophagy
《Research》2025年第1期135-148,共14页Yu-Sheng Shi Tian-Ning Yang Yu-Xiang Wang Xiang-Yu Ma Shuo Liu Yi Zhao Jin-Long Li 
supported by the National Natural Science Foundation of China(no.32172932);Key Program of Natural Science Foundation of Heilongjiang Province of China(no.ZD2021C003);China Agriculture Research System of MOF and MARA(no.CARS-35);Distinguished Professor of Longjiang Scholars Support Project(no.T201908),Heilongjiang Touyan Innovation Team Program.
The accumulation of senescent cells in kidneys is considered to contribute to age-related diseases and organismal aging.Mitochondria are considered a regulator of cell senescence process.Atrazine as a triazine herbici...
关键词:mitochondrial homeostasis cell senescence processatrazine triazine herbicide parkin mediated mitophagy senescent cells ATRAZINE renal tubular epithelial cell senescence MELATONIN 
Melatonergic Signaling Sustains Food Allergy Through FcεRI Recycling
《Research》2025年第1期752-764,共13页Youxia Wang Xinmei Zhang Ifen Hung Chunxue Liu Wenkai Ren Liangpeng Ge Hao Wang 
supported by the National Natural Science Foundation of China(U22A20510 and 32225047);Laboratory of Lingnan Modern Agriculture Project(NT2021005);Double first-class discipline promotion project(2023B10564001);National Center of Technology Innovation for Pigs(NCTIP-XD/B13).
The prevalence of food allergies is increasing dramatically and causing serious public health concerns.Notably,melatonin metabolism imbalance in patients with food allergies;however,the role of melatonin in food aller...
关键词:food allergieshoweverthe degranulation mast cells reprograms gut microbiota gut microbiota food allergy aggravates food allergy suppresses food allergy MELATONIN 
Modulation of autophagy by melatonin and its receptors:implications in brain disorders
《Acta Pharmacologica Sinica》2025年第3期525-538,共14页Chen-ze Zhu Gui-zhi Li Hai-feng Lyu Yang-yang Lu Yue Li Xiang-nan Zhang 
supported by the Fundamental Research Funds for the Zhejiang Provincial Universities(226-2023-00013);the Starry Night Science Fund of Zhejiang University Shanghai Institute for Advanced Study(SN-ZJU-SIAS-0011);the National Natural Science Foundation of China(82173792);the Jinhua Science and Technology Plan Projects(2023-3-170).
Autophagy plays a crucial role in maintaining neuronal homeostasis and function,and its disruption is linked to various brain diseases.Melatonin,an endogenous hormone that primarily acts through MT1 and MT2 receptors,...
关键词:AUTOPHAGY NEURON MELATONIN melatonin receptor brain disorders 
Exogenous melatonin enhances heat stress tolerance in sweetpotato by modulating antioxidant defense system,osmotic homeostasis and stomatal traits
《Horticultural Plant Journal》2025年第1期431-445,共15页Sunjeet Kumar Rui Yu Yang Liu Yi Liu Mohammad Nauman Khan Yonghua Liu Mengzhao Wang Guopeng Zhu 
supported jointly by the earmarked fund for CARS-10-GW2;the key research and development program of Hainan Province(Grant No.ZDYF2020226);Collaborative innovation center of Nanfan and high-efficiency tropical agriculture,Hainan University(Grant No.XTCX2022NYC21);funding of Hainan University[Grant No.KYQD(ZR)22123]。
Heat stress hinders the growth and productivity of sweetpotato plants,predominantly through oxidative damage to cellular membranes.Therefore,the development of efficient approaches for mitigating heat-related impairme...
关键词:SWEETPOTATO Heat stress MELATONIN Oxidative damage Antioxidant defense system Stomatal traits 
Potential effects of adenosine triphosphate and melatonin on oxidative and inflammatory optic nerve damage in rats caused by 5-fluorouracil
《International Journal of Ophthalmology(English edition)》2025年第2期222-228,共7页Ahmet Mehmet Somuncu Busra Parlak Somuncu Ahmet Duhan Ozbay Ibrahim Cicek Bahadir Suleyman Renad Mammadov Seval Bulut Tugba Bal Tastan Taha Abdulkadir Coban Halis Suleyman Aliyev Aydin 
AIM:To investigate the effects of adenosine triphosphate(ATP)and melatonin,which have antioxidant and antiinflammatory activities,on potential 5-fluorouracil(5-FU)-induced optic nerve damage in rats.METHODS:Twenty-fou...
关键词:adenosine triphosphate MELATONIN 5-FLUOROURACIL optic nerve damage ANTIOXIDANT ANTIINFLAMMATORY 
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