CYCLOPHOSPHAMIDE

作品数：186被引量：503H指数：11
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Antioxidant Protective Effect of Melatonin on Cyclophosphamide-Induced Premature Ovarian Failure and its Mechanism
《Proceedings of Anticancer Research》2025年第2期56-70,共15页Chongran Liu Tongtong Wei Xinyue Rao Ziqi Fan Minghui Hao Wanjing Wang Yihang Song 
2023 Special Project for Serving the National Development Strategy with Basic Scientific Research Fees from Central Universities(No.31920230188);2023 Northwestern Minzu University College-Level Innovation and Entrepreneurship Training Program(No.X202310742289);2024 National College Students’Innovation and Entrepreneurship Training Program(No.202410742005)。
Objective:To study the antioxidant protective effect and mechanism of melatonin on cyclophosphamide-induced premature ovarian failure model mice.Methods:Six-month sexually mature female Kunming mice were taken for one...
关键词：MELATONIN CYCLOPHOSPHAMIDE Premature ovarian failure ANTIOXIDATION 
Zinc oxide nanoparticles synthesized with Berberis vulgaris L.ameliorate cyclophosphamide-induced nephrotoxicity in rats
《Asian Pacific Journal of Tropical Biomedicine》2025年第4期158-168,共11页Reza Mohammadian Nader Goodarzi Mohsen Akbaribazm Hadi Cheraghi 
Objective:To examine the protective effects of green-synthesized zinc oxide nanoparticles with Berberis vulgaris L.fruit aqueous extract(BVZnONPs)on cyclophosphamide(CP)-induced nephrotoxicity in Wistar rats.Methods:3...
关键词：Nanoparticle Berberis vulgaris L Barberry KIDNEY Zinc oxide CHEMOTHERAPY 
Hepatorenoprotective effects of Lepidium draba L.extracts against cyclophosphamideinduced oxidative injuries in rats via reducing apoptosis and inflammation
《Asian Pacific Journal of Tropical Biomedicine》2025年第2期53-64,I0002,I0003,共14页Yu-Lai You Sheng Zheng Cheng-Jian Zhao Ye-Fei Chang Pei Liu Xue-Li Zeng Lian Liu 
supported by the Basic Research Joint Special General Project of Yunnan Provincial Local Universities(part)(No:202301BA070001-029,202301BA070001-044);Yunnan Province High-level Scientific and Technological Talents and Innovation Team Selection Special Young and Middle-aged Academic and Technical Leaders Reserve Talent Project(No:202405AC350067).
Objective:To investigate the protective effects of Lepidium draba L.(L.draba)on cyclophosphamide(CP)-induced hepatotoxicity and nephrotoxicity in rats.Methods:A total of 36 rats were divided into six groups as follows...
关键词：Lepidium draba CYCLOPHOSPHAMIDE Oxidative stress Antioxidant APOPTOSIS HEPATOTOXICITY NEPHROTOXICITY 
Potential of ginsenoside Rg1 to treat aplastic anemia via mitogen activated protein kinase pathway in cyclophosphamide-induced myelosuppression mouse model
《World Journal of Stem Cells》2024年第11期900-905,共6页See-Hyoung Park 
Aplastic anemia(AA)is a rare but serious condition in which the bone marrow fails to produce sufficient new blood cells,leading to fatigue,increased susceptibility to infection,and uncontrolled bleeding.In this editor...
关键词：Aplastic anemia CYCLOPHOSPHAMIDE Ginsenoside Rg1 Hematopoietic stem cells APOPTOSIS INFLAMMATION Mitogen activated protein kinase 
Geraniol alleviates cyclophosphamide-induced cardiotoxicity in mice被引量：1
《Asian Pacific Journal of Tropical Biomedicine》2024年第10期427-435,共9页Shahid Karim Rasheed A.Shaik 
The Deanship of Scientific Research at King Abdulaziz University,Jeddah,Saudi Arabia has funded this project under grant no.RG-21-166-43.
Objective:To explore the effect of geraniol on cyclophosphamide-induced cardiotoxicity.Methods:Mice were divided into five groups:the control group,the cyclophosphamide group(200 mg/kg cyclophosphamide,i.p.on day 7),t...
关键词：GERANIOL CARDIOTOXICITY Natural product CYCLOPHOSPHAMIDE INFLAMMATION APOPTOSIS 
Antioxidative effect of wheat-grain moxibustion on cyclophosphamide-induced liver injury in mice based on Nrf2-Keap1 signaling pathway
《China Medical Abstracts(Internal Medicine)》2024年第3期131-131,共1页ZHU Tao 
Objective To observe the protective effect of wheat-grain moxibustion on cyclophosphamide (CTX)-induced liver injury in mice,and explore its mechanism based on the nuclear factor E2-related factor 2 (Nrf2)-Kelch-like ...
关键词：MOXIBUSTION NRF2 protective 
Ganoderma Lucidum Spore Oil enhances the effect of cyclophosphamide via inhibiting programmed death-1 and prolongs the survival of H22 tumor-bearing mice
《Journal of Traditional Chinese Medicine》2024年第4期652-659,共8页JIANG Zhaojian CAI Hongfei YUAN Cheng CAO Lin XU Wendong HAN Yaming ZHANG Qin LI Jing WANG Qin LIU Juyan 
the Ministry of Science and Technology of China:Evaluation,Re-examination,Promotion and Demonstration of Complete Sets of Technical Equipment for Efficient and Energy-Saving Extraction and Separation of Traditional Chinese Medicine(No.2017YFC1703104);the Key Laboratory Project of Pharmaceutical Lipids in Guangdong Province:Assessment of Enterprise-Class Key Laboratory of Guangdong Province(No.2020B1212070024);the Guangdong Province Key Areas Research and Development Program Project:Research and Development on Innovative Key Technologies and Intelligent Production Equipment about Processing,Decoction,Extraction and Separation of Traditional Chinese Medicine(No.2020B1111120002)。
OBJECTIVE:To investigate the effect of Ganoderma Lucidum Spore Oil(GLSO)on the tumor growth and survival of H22 tumor-bearing mice treated with cyclophosphamide(CTX),and explore the underlying mechanism.METHODS:Allogr...
关键词：carcinoma hepatocellular CYCLOPHOSPHAMIDE SURVIVAL programmed cell death 1 receptor Ganoderma Lucidum SporeOil 
Damage effect and mechanisms of cyclophosphamide to human neuroblastoma SH-SY5Y cells
《中国药理学与毒理学杂志》2024年第8期561-574,共14页LI Jiajia WANG Jiao XIAO Wenyi WEI Donghui ZHANG Yongxiang JIANG Ning ZHOU Wenxia 
国家重点研发计划(2022YFC3500304)。
OBJECTIVE To investigate the damage effect and mechanisms of cyclophosphamide(CTX)and its active metabolite derivative 4-hydroperoxycyclophosphamide(4-HC)to human neuroblas⁃toma SH-SY5Y cells.METHODS SH-SY5Y cells wer...
关键词：CYCLOPHOSPHAMIDE 4-hydroperoxycyclophosphamide NEUROTOXICITY energy metabolism 
Parthenolide enhances the metronomic chemotherapy effect of cyclophosphamide in lung cancer by inhibiting the NF-kB signaling pathway
《World Journal of Clinical Oncology》2024年第7期895-907,共13页Zheng Cai Lang Gao Kai Hu Qi-Ming Wang 
Supported by Joint Funding of Yunnan Ministry of Science and Technology,No.2019FF002-048;and Beijing Heathco Clinical Oncology Research Foundation,No.Y-Q201802-048.
BACKGROUND Parthenolide(PTL),a sesquiterpene lactone derived from the medicinal herb Chrysanthemum parthenium,exhibits various biological effects by targeting NF-kB,STAT3,and other pathways.It has emerged as a promisi...
关键词：Lung cancer PARTHENOLIDE CYCLOPHOSPHAMIDE Rhythmic chemotherapy NF-κB pathway 
Chidamide plus prednisone,cyclophosphamide,and thalidomide for relapsed or refractory peripheral T-cell lymphoma:A multicenter phase II trial
《Chinese Medical Journal》2024年第13期1576-1582,共7页Jinhua Liang Li Wang Xiaodong Wang Guohui Cui Jianfeng Zhou Tongyao Xing Kaixin Du Jingyan Xu Luqun Wang Rong Liang Biyun Chen Jian Cheng Haorui Shen Jianyong Li Wei Xu 
National Natural Science Foundation of China(Nos.81770166,81700193,82170186,and 81720108002);Jiangsu Province’s Medical Elite Programme(No.ZDRCA2016022);Project of the National Key Clinical Specialty,the Jiangsu Provincial Special Program of Medical Science(No.BE2017751);National Science and Technology Major Project(No.2018ZX09734007);China Postdoctoral Science Foundation(No.2021M691336);Jiangsu Postdoctoral Science Foundation(No.2021K083A)
Background:Although the treatment of peripheral T-cell lymphoma(PTCL)has undergone advancements during the past several years,the response rate and long-term effects with respect to patients with PTCL remain unsatisfa...
关键词：Peripheral T-cell lymphoma CHIDAMIDE PREDNISONE CYCLOPHOSPHAMIDE THALIDOMIDE All-oral regimen 
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