THALIDOMIDE

作品数：83被引量：243H指数：10
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Chidamide plus prednisone,cyclophosphamide,and thalidomide for relapsed or refractory peripheral T-cell lymphoma:A multicenter phase II trial
《Chinese Medical Journal》2024年第13期1576-1582,共7页Jinhua Liang Li Wang Xiaodong Wang Guohui Cui Jianfeng Zhou Tongyao Xing Kaixin Du Jingyan Xu Luqun Wang Rong Liang Biyun Chen Jian Cheng Haorui Shen Jianyong Li Wei Xu 
National Natural Science Foundation of China(Nos.81770166,81700193,82170186,and 81720108002);Jiangsu Province’s Medical Elite Programme(No.ZDRCA2016022);Project of the National Key Clinical Specialty,the Jiangsu Provincial Special Program of Medical Science(No.BE2017751);National Science and Technology Major Project(No.2018ZX09734007);China Postdoctoral Science Foundation(No.2021M691336);Jiangsu Postdoctoral Science Foundation(No.2021K083A)
Background:Although the treatment of peripheral T-cell lymphoma(PTCL)has undergone advancements during the past several years,the response rate and long-term effects with respect to patients with PTCL remain unsatisfa...
关键词：Peripheral T-cell lymphoma CHIDAMIDE PREDNISONE CYCLOPHOSPHAMIDE THALIDOMIDE All-oral regimen 
Efficacy of concurrent chemoradiotherapy with thalidomide and S-1 for esophageal carcinoma and its influence on serum tumor markers被引量：1
《World Journal of Gastrointestinal Oncology》2023年第7期1262-1270,共9页Tian-Wei Zhang Peng Zhang Dong Nie Xin-Yu Che Tian-Tai Fu Yan Zhang 
BACKGROUND Although the current conventional treatment strategies for esophageal carcinoma(EC)have been proven effective,they are often accompanied by serious adverse events.Therefore,it is still necessary to continue...
关键词：THALIDOMIDE Concurrent chemoradiotherapy Esophageal carcinoma Therapeutic effect Serum tumor markers 
Thalidomide Is an Adjunct Therapy for the Refractory Systemic Juvenile Idiopathic Arthritis Patients in a Tertiary Hospital Study
《Open Journal of Rheumatology and Autoimmune Diseases》2023年第2期51-63,共13页Md. Taiyabur Rahman Mujammel Haque Farhana Faria Mohammed Mahbubul Islam Manik Kumar Talukder Mohammad Imnul Islam Shahana Akhter Rahman 
Background: Systemic JIA (sJIA) is one of the subtypes of JIA, which is most difficult to treat among all JIA cases. About 50% of sJIA cases did not respond to traditional disease modifying anti-rheumatic drugs (DMAR...
关键词：Juvenile Idiopathic Arthritis THALIDOMIDE Refractory sJIA 
Comparison and development of machine learning for thalidomideinduced peripheral neuropathy prediction of refractory Crohn’s disease in Chinese population被引量：1
《World Journal of Gastroenterology》2023年第24期3855-3870,共16页Jing Mao Kang Chao Fu-Lin Jiang Xiao-Ping Ye Ting Yang Pan Li Xia Zhu Pin-Jin Hu Bai-Jun Zhou Min Huang Xiang Gao Xue-Ding Wang 
National Natural Science Foundation of China,No.81973398,No.81730103,No.81573507 and No.82020108031;The National Key Research and Development Program,No.2017YFC0909300 and No.2016YFC0905001;Guangdong Provincial Key Laboratory of Construction Foundation,No.2017B030314030 and No.2020B1212060034;Science and Technology Program of Guangzhou,No.201607020031;National Engineering and Technology Research Center for New Drug Druggability Evaluation(Seed Program of Guangdong Province),No.2017B090903004;The 111 Project,No.B16047;China Postdoctoral Science Foundation,No.2019M66324,No.2020M683140 and No.2020M683139;Natural Science Foundation of Guangdong Province,No.2022A1515012549 and No.2023A1515012667.
BACKGROUND Thalidomide is an effective treatment for refractory Crohn’s disease(CD).However,thalidomide-induced peripheral neuropathy(TiPN),which has a large individual variation,is a major cause of treatment failure...
关键词：Thalidomide-induced peripheral neuropathy Refractory Crohn’s disease Neurotoxicity prediction models Machine learning Gene polymorphisms 
Cyclophosphamide, Thalidomide and Dexamethasone (CTD) as First-Line Therapy in Multiple Myeloma Patients: An Experience in a Clinical Haematology Centre in Dakar, Senegal
《Open Journal of Blood Diseases》2023年第1期43-50,共8页El Hadji Daouda Niang Seynabou Fall Khadim Sarr Marième Lolita Camara Aminata Dakono Awa Ndiaye Modou Moustapha Ciss Amy Thiam Serge Mwamba Fatou Samba Diago Ndiaye 
Introduction: Induction therapy followed by high-dose chemotherapy with autologous stem cell transplantation remains the gold standard for myeloma patients who can tolerate this treatment approach. In a developing cou...
关键词：MYELOMA Chemotherapy Survival 
Evaluation of the Therapeutic Significance of Arsenite and Thalidomide in Patients with Myelodysplastic Syndrome
《Journal of Clinical and Nursing Research》2022年第6期57-61,共5页Yudi Miao Ying Gao 
Objective:To analyze the therapeutic significance of arsenite and thalidomide in patients with myelodysplastic syndrome.Methods:From August 2021 to August 2022,80 patients with myelodysplastic syndrome were selected a...
关键词：ARSENITE THALIDOMIDE Myelodysplastic syndrome 
Thalidomide combined with endoscopy in the treatment of Cronkhite-Canada syndrome:A case report
《World Journal of Clinical Cases》2022年第28期10366-10374,共9页Jia-Mei Rong Meng-Lin Shi Jun-Kun Niu Juan Luo Ying-Lei Miao 
Supported by National Natural Science Foundation of China,No.82170550。
BACKGROUND Cronkhite-Canada syndrome(CCS)is a rare non-hereditary disease with a poor prognosis and a mortality rate of up to 55%.Currently,there is no standard treatment for CCS.The department of gastroenterology of ...
关键词：Cronkhite-Canada syndrome Diarrhea POLYP THALIDOMIDE Endoscopic therapy Case report 
(S)-3-aminopiperidine-2,6-dione is a biosynthetic intermediate of microbial blue pigment indigoidine被引量：1
《mLife》2022年第2期146-155,共10页Zhilong Zhang Pengwei Li Min Wang Yan Zhang Bian Wu Yong Tao Guohui Pan Yihua Chen 
supported in part by the National Key R&D Program of China(2020YFA0907700);the NSFC grants(32025002 and 31522001).
The biosynthetic investigations of microbial natural products continuously provide powerful biocatalysts for the preparation of valuable chemicals.Practical methods for preparing(S)-3-aminopiperidine-2,6-dione(2),the ...
关键词：(S)-3-aminopiperidine-2 6-dione BIOCATALYST blue pigment indigoidine THALIDOMIDE 
The efficacy and safety of thalidomide in the treatment of refractory Crohn’s disease in adults:a double-center,double-blind,randomized–controlled trial被引量：6
《Gastroenterology Report》2022年第1期519-525,共7页Xiang Peng Zi-Wen Lin Min Zhang Jia-Yin Yao Jun-Zhang Zhao Pin-Jin Hu Qian Cao Min Zhi 
supported by Academician Jie-shou Li Intestinal Barrier Special Research Fund[grant number LJS-201908C].
Background Thalidomide is applied in therapy for refractory Crohn’s disease(CD)in adults,but systematic and rigorous clinical evidence is scant.The aim was to provide theoretical references for the efficacy of thalid...
关键词：Crohn’s disease THALIDOMIDE REFRACTORY clinical remission 
Efficacy and safety of low-dose thalidomide combined with mesalazine in the treatment of refractory ulcerative colitis in adults
《Gastroenterology Report》2022年第1期653-655,共3页Jun-Rong Chen Lei Mai Jia-Chen Sun Xiang Peng Min Zhang Min Zhi 
supported by the Sun Yat-sen University Clinical Research 5010 Program[grant number 2014008];the Sixth Affiliated Hospital of Sun Yat-sen University of Horizontal Program[grant number H202101162024041054].
Introduction Inducing and maintaining clinical remission and mucosal healing is essential in the treatment of ulcerative colitis(UC),a nonspecific chronic recurrent inflammatory disorder[1].Mesalazine(5-ASA)is commonl...
关键词：HEALING clinical TREATMENT 
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