相关期刊:《Advances in Microbiology》《mLife》《Chemical Research in Chinese Universities》《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》更多>>
Surface adsorption is a convenient and readily available method for immobilizing enzymes on metal-organic frameworks(MOFs).Metal-organic framework-5(MOF-5),isoreticular metal-organic frameworks-3(IRMOF-3),and multivar...
supported by the National Key Research and Development Program of China(Nos.2020YFA0908003 and 2018YFA0901900);CAMS Innovation Fund for Medical Sciences(No.CIFMS2021-I2M-1-029).
Hydroxylation of steroid core is critical to the synthesis of steroid drugs.Direct sp^(3) C-H hydroxylation is challenging through chemical catalysis,alternatively,fungal biotransformation offers a possible solution t...
supported by the National Natural Science Foundation of China[32070028 and 32370035 to Y.-J.L.,32070125 to Y.F.,and 32170051 to Q.C.];the National Key Research and Development Program of China[2021YFC2103600 to Y.-J.L.and 2023YFC3402304 to Y.F.];the International Partnership Program of Chinese Academy of Sciences[323GJHZ2022004MI to Y.-J.L.and A.K.];Shandong Energy Institute[SEI I202142 to Y.-J.L.,SEI S202106 to Q.C.,SEI I202106 to Y.F.];QIBEBT[Grant No.QIBEBT ICP2023046 to Y.F.].E.A.B.is the incumbent of The Maynard I.and Elaine Wishner Chair of Bio-organic Chemistry.
The bioconversion of lignocellulose has attracted global attention,due to the significant potential of agricultural and forestry wastes as renewable zero-carbon resources and the urgent need for substituting fossil ca...
supported by the National Key Research and Development Program of China(2019YFA0906400);the National First-class Discipline Program of Light Industry Technology and Engineering(LITE2018-08);Postgraduate Research&Practice Innovation Program of Jiangsu Province(KYCX23_2486);We thank Prof.Shengying Li(Shandong University,China)for providing plasmids pET28a-SelFdx1499 and pET28a-SelFdR0978.
Deoxycholic acid(DCA)has been authorized by the Federal Drug Agency for cosmetic reduction of redundant submental fat.The hydroxylated product(6β-OH DCA)was developed to improve the solubility and pharmaceutic proper...
supported by the National Natural Science Foundation of China(Nos.21901058,21908040,and 21878068);Tianjin Enterprise Science and Technology Commissioner,China(21YDTPJC00810);Science Technology Research Project of Higher Education of Hebei Province,China(QN2021045);Hebei Province Postgraduate Innovation Funding Project,China(CXZZSS2021027);National College Student’s Science and Technology Innovation Project,China(202010080038)。
The worldwide application of organophosphorus pesticides(OPs)has promoted agricultural development,but their gradual accumulation in soil and water can seriously affect the central nervous system of humans and other m...
This work was funded by the 2019 Faculty Research and Professional Development award(No.2020–3069),a funding partnership between the Office of Research and Innovation and North Carolina State University.
Herein,we report a green and facile preparation and characterization procedure of copper nanoparticles stabilized on magnetically separable sodium alginate support(Cu NPs-Fe_(3)O_(4)-SAlg)using Silybum marianum seeds ...
supported in part by the National Key R&D Program of China(2020YFA0907700);the NSFC grants(32025002 and 31522001).
The biosynthetic investigations of microbial natural products continuously provide powerful biocatalysts for the preparation of valuable chemicals.Practical methods for preparing(S)-3-aminopiperidine-2,6-dione(2),the ...
Supported by the Natural Science Foundation of Guangdong Province,China(No.2018A030313151);the Senior User Project of the Research Vessel KEXUE(No.KEXUE2018G05);the Priority Research Program of the Chinese Academy of Sciences(No.XDAl 1030404);the Scientific and Technological Project of the Ocean and Fishery from Guangdong Province,China(No.A201701C12).
Bacillus sp. DL-2 was isolated from the deep sea of the Western Pacific and further utilized as novel biocatalysts to efficiently asymmetrically hydrolyze (±)-1-phenylethyl acetate. After the optimization of hydrolyt...
supported by the Chinese Academy of Medical Sciences(CAMS)Innovation Fund for Medical Sciences(CIFMS,No.2016-I2M-3–012);the Fundamental Research Funds for the Central Universities of Chinese Academy of Medical Sciences&Peking Union Medical College(2016ZX350001);Beijing Natural Science Foundation(No.7172143)
The search of new substrates with pharmaceutical and industrial potential for biocatalysts including cytochrome P450 enzymes is always challenging. Cytochrome P450 BM3 mutant 139-3, a versatile biocatalyst, exhibited ...
supported by the National Natural Science Foundation of China(21372099,21072077);the the Natural Science Foundation of Guangdong Province(10151063201000051,8151063201000016)~~
The use of biocatalysts is attracting an increasing amount of attention in chemical catalysis.Here,we have shown that bovine serum albumin(BSA),a ubiquitous,inexpensive,non-enzymatic transport protein,can serve as a...