HYDROXYLATION

作品数：100被引量：179H指数：6
导出分析报告
相关领域：理学医药卫生更多>>
相关作者：曾彩雯熊玉卿夏春华何芳张文更多>>
相关机构：南昌大学中国医学科学院北京协和医学院大连理工大学中国科学院更多>>
相关期刊：更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划重庆市自然科学基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Orchestration of diverse components in soluble methane monooxygenase for methane hydroxylation
《Chinese Journal of Catalysis》2025年第1期204-212,共9页Yunha Hwang Dong-Heon Lee Seung Jae Lee 
Methane(CH_(4))has a higher heat capacity(104.9 kcal/mol)than carbon dioxide(CO_(2)),and this has inspired research aimed at reducing methane levels to retard global warming.Hydroxylation under ambient conditions thro...
关键词：Soluble methane monooxygenase Non-hemedi-ironactivesite Methane oxidation C-Hactivation O_(2)activation 
Importance of V^(4)and optimal acid environment in the hydroxylation of inert benzene via activation of C_(sp2)-H bond
《Chinese Journal of Chemical Engineering》2024年第10期216-226,共11页Peng Dong Yang Xin Yanwei Li Xiaohui Zhang Xiaorui Wang Yu Zhao Dongqiang Zhang Haowen Ma Guixian Li 
the Support Program for Hongliu Young Teachers of Lanzhou University of Technology(02/062214);Young Talent Innovation Project of Lanzhou(2023-QN-103);Major science and technology projects of Gansu Province(22ZD6GA013).
Hydroxylation of inert benzene through the activation of the C_(sp2)-H bond is a representative reaction about the transformation of C-H bonds to C-O bonds,which has far-reaching guiding significance but remains a cha...
关键词：C_(sp2)-H activation V4^(+)/V5^(+)ratio Acid microenvironment Catalysis Support Catalyst activation 
Access to Enantioenriched Allylic Alcohols via Peptide-Mimic Phosphonium Salt-Catalyzed Asymmetric Aerobic Hydroxylation
《Chinese Journal of Chemistry》2024年第17期2017-2022,共6页Jixing Che Siqiang Fang Zanjiao Liu Jiaja He Jia-Yan Zheng Fan Wang Tianli Wang 
Financial support was provided by the National Natural Science Foundation of China(22222109,21921002,22101189 and 22371190);the National Key R&DProgramof China(2018YFA0903500);Beijing National Laboratory for Molecular Sciences(BNLMs202101);Sichuan Science Foundation for Distinguished Young Scholars(2023NSFSC1921);Sichuan Provincial Natural Science Foundation(2022NSFSC1181,24NSFSC6590);Fundamental Research Funds from Sichuan University(2020SCUNL108)and Fundamental Research Funds for the Central Universities.
The development of catalytic asymmetric methods that enable access to value-added functionalities or structures,exemplified by allylic alcohols,is a highly interesting yet challenging topic from both academic and indu...
关键词：Asymmetric catalysis Peptide-mimic phosphonium salts Aerobic hydroxylation Enantioenrichedα-allylic alcohols lon pairs Oxygen Ketones 
A H_(2)O_(2) generation-detection-regulation integrated platform for boosting the efficiency of peroxygenase-catalysed C-H oxidative hydroxylation
《Green Synthesis and Catalysis》2024年第3期153-158,共6页Xiaowang Zhang Zhuotao Tan Mengjiao Xu Wei Zhuang Hanjie Ying Zhenyu Chu Chenjie Zhu 
supported by the Program of the National Natural Science Foundation of China(Nos.22178170,22378195 and 22208156);the Six Talent Peaks Project in Jiangsu Province(No.SWYY-045);the Jiangsu Province Natural Science Foundation for Youth(No.BK20200685).
The peroxygenases are ideal biocatalysts for the selective oxyfunctionalisation of stable C-H bonds.However,the catalytic efficiency of this approach is limited due to enzyme lability toward oxidant H_(2)O_(2).Althoug...
关键词：C-H activation Enzyme catalysis Hydrogen peroxide ORGANOCATALYSIS Oxyfunctionalisation 
Chemoselective epoxidation of electron-deficient olefins with molecular oxygen via conjugated olefins epoxidation and BHT hydroxylation
《Science China Chemistry》2024年第9期3012-3018,共7页Jia Nie Huanfeng Jiang Chuanle Zhu 
supported by the National Natural Science Foundation of China(22271097);the Guangdong Basic and Applied Basic Research Foundation(2022A1515240017)。
The chemoselective epoxidation of electron-deficient olefins in the presence of electron-rich alkene moieties is reported.This chemoselective epoxidation strategy undergoes a conjugated olefin epoxidation and BHT hydr...
关键词：CHEMOSELECTIVE EPOXIDATION ALKENE fluorine molecular oxygen 
Cytochrome P450 CitCYP97B modulates carotenoid accumulation diversity by hydroxylating β-cryptoxanthin in Citrus被引量：2
《Plant Communications》2024年第6期57-72,共16页Yingzi Zhang Jiajing Jin Nan Wang Quan Sun Di Feng Shenchao Zhu Zexin Wang Shunxin Li Junli Ye Lijun Chai Zongzhou Xie Xiuxin Deng 
supported by the National Key Research and Develop-ment Program of China(2022YFF1003100);the National Natural Science Foundation of China(31930095);Modern Agro-industry Technology Research System(CARS-26).
Carotenoids in plant foods provide health benefits by functioning as provitamin A.One ofthe vital provitamin A carotenoids,β-cryptoxanthin,is typically plentiful in citrus fruit.However,little is known about the gene...
关键词：carotenoids β-cryptoxanthin cytochrome P450 CYP97B HYDROXYLATION 
A fungal CYP from Beauveria bassiana with promiscuous steroid hydroxylation capabilities
《Chinese Chemical Letters》2024年第5期218-222,共5页Yu Peng Yue Wang Tian-Jiao Chen Jing-Jing Chen Jin-Ling Yang Ting Gong Ping Zhu 
supported by the National Key Research and Development Program of China(Nos.2020YFA0908003 and 2018YFA0901900);CAMS Innovation Fund for Medical Sciences(No.CIFMS2021-I2M-1-029).
Hydroxylation of steroid core is critical to the synthesis of steroid drugs.Direct sp^(3) C-H hydroxylation is challenging through chemical catalysis,alternatively,fungal biotransformation offers a possible solution t...
关键词：Fungal CYPs Steroid hydroxylase Beauveria bassiana Promiscuous biocatalyst Molecular dynamics 
Regioselective and enantioselective propargylic hydroxylations catalyzed by P450tol monooxygenases
《Bioresources and Bioprocessing》2024年第1期855-863,共9页Xu Deng Cheng-Cheng Song Wen-Jing Gu Yu-Jie Wang Lu Feng Xiao-Jian Zhou Ming-Qiang Zhou Wei-Cheng Yuan Yong-Zheng Chen 
financial support from the National Natural Science Foundation of China(No.32271537 and 22061049);the Science and Technology Department of Guizhou province(QKHJCZK2021-036 and QKHRCPTGCC-2023-003);the Science and Technology Department of Zunyi(ZSKRPT-2020-5,ZSKH-2018-3,ZSKRPT-2021-5);Zunyi Medical University(QKH-2018-5772-014).
Regioselective and enantioselective hydroxylation of propargylic C-H bonds are useful reactions but often lack appropriate catalysts.Here a green and efficient asymmetric hydroxylation of primary and secondary C-H bon...
关键词：BIOCATALYSIS HYDROXYLATION P450 monooxygenase Propargylic alcohols ENANTIOSELECTIVITY 
Functional characterization of CYP81C16 involved in the tanshinone biosynthetic pathway in Salvia miltiorrhiza被引量：2
《Chinese Journal of Natural Medicines》2023年第12期938-949,共12页REN Li LUO Linglong HU Zhimin MA Ying WANG Jian CHENG Yatian JIN Baolong CHEN Tong TANG Jinfu CUI Guanghong GUO Juan HUANG Luqi 
This work was supported by the National Key R&D Program of China(Nos.2020YFA0908000,2018YFA0900600);the National Natural Science Foundation of China(Nos.82003904,81822046);the Fundamental Research Funds for the Central public welfare research institutes(No.ZZ13-YQ-083);a Scientific and Technological Innovation Project of China Academy of Chinese Medical Sciences(No.CI2021A04110);Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(No.ZYYCXTD-D-202005);a key project at central government level(the ability to establish sustainable use of valuable Chinese medicine resources;2060302,China).
Danshen,the dried roots and rhizomes of Salvia miltiorrhiza Bunge(S.miltiorrhiza),is widely used in the treatment of cardiovascular and cerebrovascular diseases.Tanshinones,the bioactive compounds from Danshen,exhibit...
关键词：Salvia miltiorrhiza TANSHINONE Biosynthetic pathway Cytochrome P450 HYDROXYLATION Neocryptotanshinone 
Efficient stereoselective hydroxylation of deoxycholic acid by the robust whole-cell cytochrome P450 CYP107D1 biocatalyst被引量：1
《Synthetic and Systems Biotechnology》2023年第4期741-748,共8页Chixiang Sun Baodong Hu Yanchun Li Zhimeng Wu Jingwen Zhou Jianghua Li Jian Chen Guocheng Du Xinrui Zhao 
supported by the National Key Research and Development Program of China(2019YFA0906400);the National First-class Discipline Program of Light Industry Technology and Engineering(LITE2018-08);Postgraduate Research&Practice Innovation Program of Jiangsu Province(KYCX23_2486);We thank Prof.Shengying Li(Shandong University,China)for providing plasmids pET28a-SelFdx1499 and pET28a-SelFdR0978.
Deoxycholic acid(DCA)has been authorized by the Federal Drug Agency for cosmetic reduction of redundant submental fat.The hydroxylated product(6β-OH DCA)was developed to improve the solubility and pharmaceutic proper...
关键词：OleP Deoxycholic acid HYDROXYLATION Redox partners Whole-cell catalysis 
全选清除导出
共10页<12345678910>
检索报告 对象比较 聚类工具 使用帮助 返回顶部