supported by Natural Science Foundation:of Guangdong,China(No.2024A04J5216);the Technology Project of Guangzhou City(Guangdong,China)(No.202102020937);the Outstanding Youth Development Scheme of Nanfang Hospital,Southern Medical University(Guangdong,China)(No.2019J011).
Multiple myeloma(MM)is the second most common hematologic malignancy and is characterized by the expansion of clonally plasma cells and related organ or tissue damage.1 The clinical behavior,response,and survival of M...
funded by the National Natural Science Foundation of China(No.81471165,81670190,81670189,81870160,81971108,82270207,and 82370202);the Science and Technology Development Program of the Jilin Province(No.20190201042JC,20190201163JC,YDZJ202301ZYTS021,and 20210509010RQ);Interdisciplinary Integration and Innovation Project of Jilin University.
Emerging evidence indicates that the fitness/frailty status of elderly patients with multiple myeloma(MM)is highly dynamic,influenced by factors such as aging,disease progression,and treatment.This underscores the imp...
the Sun Yat-sen University Hundred Talents Program(China)(No.PT19200101);Natural Science Foundation of Guangdong Province,China(No.2022A1515010290);Guangdong Province Science and Technology Planning Project of China(No.2020A1414010033);Guangzhou Science and Technology Planning Project of China(No.202102020430);YL was supported,in part,by Sun Yat-sen University Start-up Funding(China)(No.201603);H-XL was supported by the National Natural Science Foundation of China(No.81773103);the Natural Science Foundation of Guangdong Province,China(No.2017A030313617).
Multiple myeloma(MM)is the second most common hematological tumor.It is characterized by high drug resistance,easy recurrence,and poor prognosis,and remains incurable.Various models or scoring modalities can be used t...
Objective To investigate the prognostic value of the Second Revision of the International Staging System (R2-ISS) in patients with newly diagnosed multiple myeloma(NDMM).Methods The retrospective study was performed i...
Background: Amyloidosis is a disease characterized by the deposition of fibrillar proteins in tissues. The nature of the protein defines the type of amyloidosis. Cardiac involvement is most often secondary to deposits...
approved by the Ethics Committee of Tokyo Medical University(No.T2023-0105).
Aim:This study aimed to investigate drug candidates and their efficacy in treating refractory multiple myeloma(MM)despite significant therapeutic advances and the introduction of novel agents.Our study focused on how ...
Objective To evaluate the efficacy and safety of autologous hematopoietic stem cell transplantation (autoHSCT) for the treatment of multiple myeloma (MM) in elderly patients aged over 65 years.Methods In this retrospe...
Objective To evaluate the efficacy and safety of bendamustine combined with pomalidomide and dexamethasone(BPD regimen)in the treatment of relapsed multiple myeloma(MM)with extramedullary disease.Methods This open,sin...
Multiple myeloma (MM) is both a complex and heterogeneous disease. Cytogenetic and molecular abnormalities lead to resistance to treatment and transformation to plasma cell leukemia, which is defined by the presence i...