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作品数：310被引量：487H指数：11
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相关机构：北京大学第三军医大学西南医院中国人民解放军总医院中国科学院更多>>
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Predictors of Survival and Relapse among Children Diagnosed with Acute Leukemia in Northen Tanzania
《Open Journal of Pediatrics》2025年第1期52-65,共14页Arnold Likiliwike Yotham Gwanika Heronima Joas Aisa Shayo Linda Kissila Esther Majaliwa 
Background: Acute Leukemia is the most common childhood cancer, with two main types: ALL and AML. In Tanzania, recent improvements in treatment and survival have been noted, but the latest data is from 2013. This stud...
关键词：Acute Leukemia RELAPSE SURVIVAL 
An assessment model for efficacy of autologous CD19 chimeric antigen receptor T-cell therapy and relapse or refractory diffuse large B-cell lymphoma risk
《Chinese Medical Journal》2025年第1期108-110,共3页Bin Xue Yifan Liu Min Zhang Gangfeng Xiao Xiu Luo Lili Zhou Shiguang Ye Yan Lu Wenbin Qian Li Wang Ping Li Aibin Liang 
supported by grants from the National Key R&D Program of China(No.2021YFA1100800);National Natural Science Foundation of China(Nos.81830004 and 82070168);Translational Research Grant of NCRCH(No.2020ZKZC04);Shanghai Municipal Health Commission(No.2020CXJQ02);Cultivation project of National Natural Science Foundation of Shanghai Tongji Hospital(No.GJPY2332).
To the Editor:Autologous CD19 chimeric antigen receptor(CAR)T-cell therapy has emerged as a crucial treatment option for patients with relapsed or refractory diffuse large B-cell lymphoma(r/r DLBCL).[1]While CAR-T-cel...
关键词：therapeutic efficacy chimeric antigen REFRACTORY predictive model Chimeric Antigen Receptor T cell therapy diffuse large B cell lymphoma 
Progress in research on risk factors and prediction models for alcohol consumption after liver transplantation in patients with alcoholic liver disease
《感染控制(英文)》2024年第4期42-53,共12页Yulin Zheng Lili Zhang Xin Liu Chaoqun Wang Jingjing Zhi Guojing Sui Shuangmei Xi Yanmei Gu 
Beijing Municipal Hospital Scientific Research Cultivation Plan Project(PX2022068);Beijing Youan Hospital,Capital Medical University,Young Talent Incubation Project(New Seed Plan)(BJYAYYYN2023-19).
Patients with alcoholic liver disease who resume alcohol consumption after liver transplantation are at risk of graft dysfunction,which poses a serious threat to their survival.This review summarizes the definitions a...
关键词：Alcoholic liver disease liver transplantation relapse drinking influencing factors predictive models 
Breast relapse of myeloid sarcoma and SARS-CoV-2 infection following hematopoietic stem cell transplantation in mixed-phenotype acute leukemia: a case report
《Emergency and Critical Care Medicine》2024年第4期191-195,共5页Chaolu Hu Hui Liu Song Zhao Mengmeng Shang Rong Ma Xiaoyuan Dong Jiang Zhu 
Background:Mixed-phenotype acute leukemia is a rare,high-risk subtype of acute leukemia.Myeloid sarcoma is a localized tumor formed by the proliferation and infiltration of primitive or immature myeloid cells outside ...
关键词：BREAST Case report COVID-19 Myeloid sarcoma Mixed-phenotype acute leukemia 
Primary malignant melanoma of the breast:A case report without relapse
《Malignancy Spectrum》2024年第4期339-345,共7页Alejandro Caballero Mario Perez Issis Rodriguez 
Objective:This study aimed to report the treatment and outcomes of a patient with primary malignant melanoma of the breast parenchyma using mastectomy as the main treatment.Patient and methods:A 67-year-old female pre...
关键词：MELANOMA BREAST MALIGNANCY MASTECTOMY 
Pre-transplantation levels of lysine(K)-specific methyltransferase 2A(KMT2A)partial tandem duplications can predict relapse of acute myeloid leukemia patients following haploidentical donor hematopoietic stem cell transplantation
《Blood Science》2024年第4期52-59,共8页Dao-Xing Deng Xiao-Hang Ma Ze-Hua Wu Xiao-Hui Zhang Lan-Ping Xu Yu Wang Chen-Hua Yan Huan Chen Yu-Hong Chen Wei Han Feng-Rong Wang Jing-Zhi Wang Xiao-Jun Huang Xiao-Su Zhao Xiao-Dong Mo 
supported by the National Key Research and Development Program of China(2021YFC2500300,2022YFC2502606);the Grants from the Beijing Municipal Science and Technology Commission(Z221100007422008);Major Program of the National Natural Science Foundation of China(82293630,82293633);CAMS Innovation Fund for Medical Sciences(2022-I2M-C&T-B-121,2023-I2MC&T-B-123);Peking University People’s Hospital Research and Development Funds(RD2023-08);Tongzhou District Distinguished Young Scholars(JCQN2023009);the Fundamental Research Funds for the Central Universities。
We aimed to identify dynamic changes of lysine(K)-specific methyltransferase 2A partial tandem duplications(KMT2A-PTD)before and after haploidentical donor hematopoietic stem cell transplantation(HID HSCT)and explore ...
关键词：Acute myeloid leukemia Allogeneic hematopoietic stem cell transplantation HAPLOIDENTICAL KMT2A-PTD RELAPSE 
Subcutaneous daratumumab in Chinese patients with relapsed or refractory multiple myeloma:an open-label,multicenter,phase 1 study(MMY1010)
《Blood Science》2024年第3期42-47,共6页Gang An Zheng Ge Hongmei Jing Jing Liu Guoping Yang Ru Feng Zhongyuan Xu Ming Qi Jianping Wang Juanjuan Song Wei Zhou Binbin Sun Dian Zhu Xi Chen Canchan Cui Lugui Qiu 
Despite recent progress in multiple myeloma(MM)treatments,most patients will relapse and require additional treatment.Intravenous daratumumab,a human IgGκmonoclonal antibody targeting CD38,has shown good efficacy in ...
关键词：Chinese Daratumumab Multiple myeloma PHARMACOKINETIC Relapse/refractory Safety SUBCUTANEOUS 
Statistical evaluation of cluster formation of relapse in neuromyelitis optica spectrum disorder
《Neural Regeneration Research》2024年第9期1888-1889,共2页Tetsuya Akaishi Ichiro Nakashima 
Evaluating the cluster formation of clinical attacks in chronic relapsing diseases is an important statistical issue because the presence of attack clusters may influence therapeutic strategies for relapse prevention....
关键词：AQP4 RELAPSE 
Next-generation sequencing reveals relapse and leukemia-free survival risks in newly diagnosed acute myeloid leukemia treated with CAG regimen combined with decitabine
《Cancer Pathogenesis and Therapy》2024年第2期112-120,共9页Sai Huang Peng Chen Lu Wang Lingmin Xu Nan Wang Fei Li Liping Dou Daihong Liu 
supported by the National Natural Science Foundation of China(Nos.82200169,82270162,82270224,and 82070178);the National Key R&D Program of China(No.2021YFA1100904);the Beijing Natural Science Foundation of China(No.7222175);the Military Medical Support Innovation and Generate Special Program(No.21WQ034);the Special Research Fund for Health Protection(No.21BJZ30).
Background:Acute myeloid leukemia(AML)is a heterogeneous hematopoietic malignancy whose prognosis is associated with several biomarkers.Decitabine,a deoxyribonucleic acid(DNA)methyltransferase(DNMT)in-hibitor,combined...
关键词：Acute myeloid leukemia Next-generation sequencing Prognosis DNA methyltransferase CHEMOTHERAPY 
Clinical outcomes of cessation of nucleoside/nucleotide analogues in Chinese patients with HBeAg-negative chronic hepatitis B
《iLIVER》2024年第2期22-27,共6页Fengyi Li Yadong Zhang Chao Liu Juan Li Dali Zhang Yinjie Gao 
supported by the Beijing Municipal Foundation for Clinical Research[Z181100001718033];the Project for Prevention and Treatment of AIDS and Viral Hepatitis[2018ZX10301-404];the National Major Science and Technology Project of China[2019YFC0840704].
Background and aims:Cessation of nucleoside/nucleotide analogue(Nuc)therapy in patients with HBeAg-negative chronic hepatitis B(CHB)remains controversial.Methods:In this prospective,single-center cohort study,we recru...
关键词：Nucleoside analogues Nucleotide analogues Therapy cessation HBeAg-negative Clinical relapse 
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