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Single-cell transcriptomic sequencing identifies subcutaneous patient-derived xenograft recapitulated medulloblastoma
《Animal Models and Experimental Medicine》2025年第3期458-472,共15页Jiayu Gao Yahui Zhao Ziwei Wang Fei Liu Xuan Chen Jialin Mo Yifei Jiang Yongqiang Liu Peiyi Tian Yanong Li Kaiwen Deng Xueling Qi Dongming Han Zijia Liu Zhengtao Yang Yixi Chen Yujie Tang Chunde Li Hailong Liu Jiankang Li Tao Jiang 
National Key Research and Development Program of China,Grant/Award Number:2022ZD0210100;Beijing Nova Star Program,Grant/Award Number:2022002;Natural Science Foundation of Beijing and Haidian Collaboration Foundation,Grant/Award Number:L232079;National Natural Science Foundation of China,Grant/Award Number:82172608,82273343,81902975 and 82101356;Capital Medical University Fund for Excellent Young Scholars,Grant/Award Number:KCB2304。
Background:Medulloblastoma(MB)is one of the most common malignant brain tumors that mainly affect children.Various approaches have been used to model MB to facilitate investigating tumorigenesis.This study aims to com...
关键词：experimental models MEDULLOBLASTOMA single-cell sequencing sPDX 
Aggregation-Induced Emission-Active Photosensitizer-Mediated Photodynamic Therapy for Anti-Psoriasis
《Research》2025年第1期935-954,共20页Ping Zhu Zhaoji Wu Zhilu Yang Tingting Tang Yunhui Liao Wen Zhao Ying Huang Tao Chen Junjie Li Chunmei Nong Zhenzhen Wu Guodong Hu Yanshan Liu Yinghua Chen 
supported by the Natural Science Funding of Guangdong Province(2022A1515012312 and 2021A1515010023);the National Natural Science Funding of China(82070083);Dongguan Social development technology projects Science and Technology Planning Project(20231800940792).
Hyperproliferative keratinocytes and subcutaneous inflammation contribute to the characteristic symptoms of psoriasis,including erythema,scales,or scaly plaques on the skin.These symptoms significantly affect patients...
关键词：PSORIASIS PHOTOSENSITIZER hyperproliferative keratinocytes subcutaneous inflammation scaly plaques organic photosensitizer photodynamic therapy treatment strategies 
Self-adhesive ultrasound-mediated triboelectric nanogenerator device for subcutaneous antibacterial treatment and accelerated wound healing
《Science China Materials》2025年第1期261-269,共9页Xiaowei Lv Chunmei Guo Sihan Luo Lina Qi Jingyi Shi Jianhang Zhao Ying Chen Aijun He Quli Fan 
Fundamental Research Funds of the National Natural Science Foundation of China (32071724,52373142)。
Electrical stimulation therapy has excellent potential for wound healing and tissue regeneration.However,conventional approaches often require external power sources and implantable electrodes,which can limit their pr...
关键词：ultrasound mediation triboelectric nanogenerator antibacterial wound healing 
Abdominal wall hematoma related to subcutaneous low-molecular-weight heparin injection following coronary intervention therapy:case presentation
《Journal of Geriatric Cardiology》2025年第1期214-218,共5页Xiao-Hua LIU Yi-Zhou XU 
Subcutaneous administration of low-molecularweight heparin(LMWH)has been widely accepted as an effective anticoagulation therapy and is frequently used for patients to prevent thromboembolic events.While the usually s...
关键词：INJECTION HEPARIN HEMATOMA 
Liquid Subcutaneous Levodopa-Carbidopa ND0612 Effects on Motor Symptoms in Individuals with Parkinson’s Disease: A Systematic Review and Meta-Analysis
《Advances in Parkinson's Disease》2024年第2期9-25,共17页Paula Abola Mitchell Wolden Kristin Lefebvre 
Objective: In the manuscript titled “Liquid subcutaneous Levodopa-Carbidopa ND0612 effects on motor symptoms in individuals with Parkinson’s Disease: A systematic review and meta-analysis”, the objective was to con...
关键词：Parkinson’s Disease ND0612 Levodopa-Carbidopa Motor Symptoms Motor Complications UPDRS 
Subcutaneous daratumumab in Chinese patients with relapsed or refractory multiple myeloma:an open-label,multicenter,phase 1 study(MMY1010)
《Blood Science》2024年第3期42-47,共6页Gang An Zheng Ge Hongmei Jing Jing Liu Guoping Yang Ru Feng Zhongyuan Xu Ming Qi Jianping Wang Juanjuan Song Wei Zhou Binbin Sun Dian Zhu Xi Chen Canchan Cui Lugui Qiu 
Despite recent progress in multiple myeloma(MM)treatments,most patients will relapse and require additional treatment.Intravenous daratumumab,a human IgGκmonoclonal antibody targeting CD38,has shown good efficacy in ...
关键词：Chinese Daratumumab Multiple myeloma PHARMACOKINETIC Relapse/refractory Safety SUBCUTANEOUS 
Characteristics and mechanisms of subcutaneous and visceral adipose tissue aging
《Chinese Journal of Plastic and Reconstructive Surgery》2024年第2期94-97,共4页Peng Xu Yikai Wang Kai Liu 
the National Natural Science Foundation of China(grant no.82272289).
Aging is one of the most significant health challenges worldwide and is a primary cause of chronic diseases and physiological decline.Among the myriad changes that occur with aging,alterations in adipose tissue distri...
关键词：White adipose tissue Subcutaneous adipose tissue Visceral adipose tissue Adipose tissue aging 
Waist subcutaneous soft tissue metastasis of rectal mucinous adenocarcinoma: A case report
《World Journal of Clinical Cases》2024年第14期2412-2419,共8页Zi-Xing Gong Guo-Lei Li Wen-Min Dong Zhao Xu Rui Li Wen-Xia Lv Jing Yang Zhong-Xin Li Wei Xing 
BACKGROUND Rectal mucinous adenocarcinoma(MAC)is a rare pathological type of rectal can-cer with unique pathological features and a poor prognosis.It is difficult to diag-nose and treat early because of the lack of sp...
关键词：Colorectal cancer Rectal mucinous adenocarcinoma Cancer metastasis Subcutaneous soft tissue HEMATOGENOUS Case report 
Impact of hepatitis B immunoglobulin mode of administration on treatment experiences of patients after liver transplantation: Results from an online survey
《World Journal of Transplantation》2024年第3期144-155,共12页Giorgia Rizza Kyriaki Glynou Masha Eletskaya 
BACKGROUND Hepatitis B immunoglobulin(HBIG)in combination with a potent nucleos(t)ide analog is considered the standard of care for prophylaxis against hepatitis B virus(HBV)reinfection after liver transplantation for...
关键词：Hepatitis B immunoglobulin Liver transplantation SUBCUTANEOUS INTRAMUSCULAR INTRAVENOUS Patient satisfaction 
Cold-Induced Reprogramming of Subcutaneous White Adipose Tissue Assessed by Single-Cell and Single-Nucleus RNA Sequencing
《Research》2024年第1期763-778,共16页Qing Liu Qiaoyun Long Jiayu Zhao Wenjie Wu Zexin Lin Wei Sun Ping Gu Tuo Deng Kerry Martin Loomes Donghai Wu Alice P.S.Kong Jingying Zhou Alfred S.Cheng Hannah Xiaoyan Hui 
National Natural Science Foundation of China(NSFC)-Excellent Young Scientists Fund(81922079);Hong Kong Research Grants Council General Research Fund(17123419);Lo Kwee-Seong Biomedical Research Start-up Fund(7106480 and 7106481).
Adipose browning has demonstrated therapeutic potentials in several diseases.Here,by conducting transcriptomic profiling at the single-cell and single-nucleus resolution,we reconstituted the cellular atlas in mouse in...
关键词：EVOKED programming GENERATING 
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