Objective To analyze the market environment of heparin,and to provide reference for the development of the heparin industry in China.Methods The international market size and competition pattern of heparin was investi...
supported primarily by the National Natural Science Foundation of China(22075191,21774089,and 21935008);the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD);the Key Laboratory of Polymeric Materials Design and Synthesis for Biomedical Function,Soochow University;the Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application,Soochow University.
Surface endothelialization is a promising way to improve the hemocompatibility of biomaterials.However,current surface endothelialization strategies have limitations.For example,various surface functions are not well ...
Subcutaneous administration of low-molecularweight heparin(LMWH)has been widely accepted as an effective anticoagulation therapy and is frequently used for patients to prevent thromboembolic events.While the usually s...
supported by grants from the National Key Research and Development Program of China(2021YFA1101500);the National Natural Science Foundation of China(81974221,81974009,and 92049119);the Hubei Innovation Group Foundation(2022CFA019);the General Program of Health Commission of Hubei Province(WJ2023M126).
Mesenchymal stem cell-derived extracellular vesicles(MSC-EVs)have obvious advantages over MSC therapy.But the strong procoagulant properties of MSC-EVs pose a potential risk of thromboembolism,an issue that remains in...
Controlled delivery of proteins and other biologics is a growing medium of therapy for diseases previously untreatable.Here we report a self-assembling,tunable vesicle for the controlled delivery of growth factors and...
BACKGROUND Bivalirudin,a direct thrombin inhibitor,is used in anticoagulation therapies as a substitute for heparin,especially during cardiovascular procedures such as percutaneous coronary intervention.AIM To explore...
Heparin-induced thrombocytopenia thrombosis(HITT)is a rare and potentially life-threatening complication after abdominal surgery,and it always occurs after the prophylactic or therapeutic use of heparin.HITT after pan...
Supported by the National Natural Science Foundation of China Youth Training Project,No.2021GZR003;Medical-engineering Interdisciplinary Research Youth Training Project,No.2022YGJC001.
BACKGROUND Posthepatectomy liver failure(PHLF)is one of the most important causes of death following liver resection.Heparin,an established anticoagulant,can protect liver function through a number of mechanisms,and t...
supported by the Key Projects of the National Natural Science Foundation of China(81830055);National Natural Science Foundation of China(82001966);Outstanding Scientist Project of Chongqing(cstc2022ycjh-bgzxm0186);Special Funding for Postdoctoral Research of Chongqing(2021XM1020).
Small-diameter tissue-engineered vascular grafts(sdTEVGs)have garnered significant attention as a potential treatment modality for vascular bypass grafting and replacement therapy.However,the intimal hyperplasia and t...
Natural Science Foundation of Xinjiang Uygur Autonomous Region(No.2019D01C244);Special Research Project for Health and Young Medical Science and Technology Talents in Xinjiang Uygur Autonomous Region(No.WJWY-202142)。
Objective:The perioperative period of major orthopedic surgery is associated with a high risk of thrombosis,but the best chemopreventive agent for thrombosis prophylaxis is still inconclusive.For this reason,this pape...