BIVALIRUDIN

作品数:20被引量:56H指数:4
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相关领域:医药卫生更多>>
相关作者:张亚臣相银唐勇更多>>
相关机构:上海交通大学医学院附属新华医院青岛科技大学南京工业大学更多>>
相关期刊:《Chinese Medical Journal》《World Journal of Cardiology》《Cardiovascular Innovations and Applications》《现代化工》更多>>
相关基金:国家自然科学基金中国博士后科学基金更多>>
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Bivalirudin for anticoagulation in elderly acute coronary syndrome:Effects on myocardial microcirculation and adverse events
《World Journal of Clinical Cases》2025年第13期47-51,共5页Chun-Yao Cheng Wen-Rui Hao Tzu-Hurng Cheng 
The management of acute coronary syndrome(ACS)in older patients remains challenging because standard anticoagulants often fail to yield optimal outcomes.Bivalirudin,a direct inhibitor of thrombin,serves as an alternat...
关键词:BIVALIRUDIN Acute coronary syndrome Myocardial microcirculation Elderly patients ANTICOAGULATION 
Effect of bivalirudin on myocardial microcirculation and adverse events after interventional therapy in older patients with acute coronary syndrome被引量:1
《World Journal of Clinical Cases》2024年第22期4890-4896,共7页Ya-Kun Du Li-Jun Cui Hong-Bo Gao 
BACKGROUND Bivalirudin,a direct thrombin inhibitor,is used in anticoagulation therapies as a substitute for heparin,especially during cardiovascular procedures such as percutaneous coronary intervention.AIM To explore...
关键词:BIVALIRUDIN HEPARIN Acute coronary syndrome Corrected thrombolysis in myocardial infarction flow frame count Thrombolysis in myocardial infarction myocardial perfusion classification 
基于连续流动化学的Bivalirudin绿色合成方法的研究
《现代化工》2023年第11期140-144,149,共6页王振炜 刘豪 黄鼎旻 苏贤斌 
省部共建生态化工协同创新中心人才基金资助(1203042904001419)。
提出了一种新型绿色多肽合成方法,并成功将该方法应用于水蛭素的二十肽类似物Bivalirudin的合成。以苄氧羰基(Cbz)为氨基保护基,利用钯炭装填柱快速脱去Cbz保护,偶联反应及其后处理在微通道反应器内完成,实现了偶联-后处理-脱保护全体...
关键词:连续流动化学 微通道反应器 比伐芦定 多肽合成 
Rationale and Design of a Randomized Controlled Trial of Bivalirudin with a Prolonged High-Dose Infusion Versus Heparin Monotherapy During Primary Percutaneous Coronary Intervention in Patients with Acute ST-Segment Elevation Myocardial Infarction:The BRIGHT-4 Trial被引量:1
《Cardiology Discovery》2022年第4期226-230,共5页Zhenyang Liang Yi Li Gregg W.Stone Yaling Han 
supported by the Chinese Society of Cardiology’s Foundation.
Intravenous anticoagulant therapy is critical to prevent ischemic events without increasing the risk of bleeding in patients with ST-segment elevation myocardial infarction(STEMI)undergoing primary percutaneous corona...
关键词:HEPARIN BIVALIRUDIN ST-segment elevation myocardial infarction Primary percutaneous coronary intervention 
Efficacy and safety of bivalirudin without post-procedure infusion in patients with coronary heart disease during elective percutaneous coronary intervention:a real-world study被引量:4
《Chinese Medical Journal》2022年第1期116-118,共3页Ping Wang Xin Zhao Qimin Yuan Xiaoxue Yu Lin Yang Xiaozeng Wang 
To the Editor:Antithrombotic therapy is essential to prevent adverse ischemic events during and after percutaneous coronary intervention(PCI).Anticoagulation during PCI is most commonly achieved with heparin or bivali...
关键词:patients CORONARY INFUSION 
Bivalirudin in Primary PCI: Can Its Glory Being Restored?被引量:1
《Cardiology Discovery》2021年第3期179-194,共16页Yang Li Yi Li Gregg W.Stone Yaling Han 
supported by the Key Research and Development Program of Liaoning Province(2020JH 2/10300167);Project of Science and Technology Plan of Shenyang(19-112-4-051);Cardiacare Sponsored Optimizing Antithrombotic Research Fund(BJUHFCSOARF201901-06).
Intravenous anticoagulant therapy is critical to prevent ischemic recurrences and complications without increasing the risk of bleeding in patients with ST-segment elevation myocardial infarction (STEMI) undergoing pr...
关键词:BIVALIRUDIN HEPARIN ST-segment elevation myocardial infarction Primary percutaneous coronary intervention 
Effects of Bivalirudin and Unfractionated Heparin on Liver and Renal Function in Chinese Patients with Coronary Artery Disease Undergoing Coronary Angiography with/without Percutaneous Coronary Intervention被引量:3
《Journal of Clinical and Translational Hepatology》2021年第4期477-483,共7页Qiaowei Jia Jia Hu Wenfeng Ji Liansheng Wang Enzhi Jia 
This study received support from the National Natural Science Foundations of China(No.81970302).
Background and Aims:Unfractionated heparin(UFH)and bivalirudin are widely used as anticoagulants in cardiovascular medicine,including for thrombosis prevention during coronary angiography(CAG)and percutaneous coronary...
关键词:BIVALIRUDIN Unfractionated heparin Coronary artery disease Coro-nary angiography Percutaneous coronary intervention Liver function 
Anticoagulation with direct thrombin inhibitors during extracorporeal membrane oxygenation被引量:13
《World Journal of Critical Care Medicine》2019年第6期87-98,共12页Barry Burstein Patrick M Wieruszewski Yan-Jun Zhao Nathan Smischney 
Use of extracorporeal membrane oxygenation to support patients with critical cardiorespiratory illness is increasing.Systemic anticoagulation is an essential element in the care of extracorporeal membrane oxygenation ...
关键词:EXTRACORPOREAL membrane OXYGENATION ANTICOAGULANTS Antithrombins BIVALIRUDIN ARGATROBAN Heparin 
Effects of bivalirudin on acute myocardial infarction in patients undergoing emergency percutaneous coronary intervention被引量:3
《South China Journal of Cardiology》2018年第4期237-243,共7页SUN Xue-yu ZHANG Yu-ying HAN Zeng-lei 
supported by Qingdao Municipal Health Commission Planning Project(No.2015-WJZD066)
Background It.s an effective treatment to implement percutaneous coronary intervention in acute myocardial infarction patients,which rapidly achieve coronary reperfusion. However,many patients with no-reflow,leading t...
关键词:acute myocardial infarction ANGIOPLASTY NO-REFLOW BIVALIRUDIN 
Use of Bivalirudin for Anticoagulation in Interventional Cardiovascular Procedures
《Cardiovascular Innovations and Applications》2018年第B07期163-174,共12页Zhen Ge Jaya Chandrasekhar Roxana Mehran 
Anticoagulation is imperative to reduce the incidence of thrombotic complications in patients undergoing percutaneous interventional cardiovascular procedures;however,this is at the expense of increased risk of bleedi...
关键词:BIVALIRUDIN ANTICOAGULATION INTERVENTIONAL CARDIOVASCULAR PROCEDURES 
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