The management of acute coronary syndrome(ACS)in older patients remains challenging because standard anticoagulants often fail to yield optimal outcomes.Bivalirudin,a direct inhibitor of thrombin,serves as an alternat...
Antiphospholipid syndrome(APS)is a systemic autoimmune disorder characterized by the presence of antiphospholipid antibodies and is associated with thrombotic events and pregnancy complications.The classification and ...
Lung transplantation(LT)is now an accepted therapy for end stage lung disease in appropriate patients.Atrial arrhythmias(AA)can occur after LT.Early AA after LT are most often atrial fibrillation,whereas late arrhythm...
Lung transplantation(LT)is currently a surgical therapy option for end-stage lung disease.Venous thromboembolism(VTE),which can occur after LT,is associated with significant morbidity and mortality.Because of improved...
BACKGROUND Patients with inflammatory bowel disease are at a 2-8-fold higher risk of deve-loping venous thromboembolism(VTE)as compared to the general population.Although the exact pathogenesis is unclear,the literatu...
BACKGROUND Inflammatory bowel disease(IBD),with its rising prevalence rates is associated with an increased risk of cardiovascular and thromboembolic events.Antiplatelets and/or anticoagulants agents are often prescri...
supported by the National Natural Science Foundation of China(82027802,82102220,61975017,82101389,82171278);the Research Funding on Translational Medicine from Beijing Municipal Science and Technology Commission(Z221100007422023);the Beijing Hospitals Authority Clinical Medicine Development of special funding support(YGLX202325);the Nonprofit Central Research Institute Fund of Chinese Academy of Medical(2023-JKCS-09);the Beijing Association for Science and Technology Youth Talent Support Program(BYESS2022081);the Science and Technology Innovation Service Capacity Building Project of Beijing Municipal Education Commission(11000023T000002157177).
Aim:Approximately 21%of patients with cerebral venous sinus thrombosis(CVST)are refractory to anticoagulation treatment and face poor prognosis.These patients may benefit from endovascular therapy.Although numerous st...
It is no surprise that clotting and bleeding are competing physiologic risks,and balancing the risks of venous thromboembolism(VTE)and postoperative bleeding is an essential yet challenging task in modern surgical pra...
Atrial fibrillation (AF) is the most common arrhythmia in the world, and its management relies on restoring sinus rhythm through external electrical shock and controlling the heart rate. This procedure should be perfo...
BACKGROUND:Patients who present to the emergency department(ED)for suspected pulmonary embolism(PE)are often on active oral anticoagulation(AC).However,the diagnostic yield of computed tomography pulmonary angiography...