BACKGROUND Currently,very few studies have examined the analgesic effectiveness and safety of dexmedetomidine-assisted intravenous-inhalation combined general anesthesia in laparoscopic minimally invasive surgery for ...
Background In ischaemic stroke,minor deficits(National Institutes of Health Stroke Scale(NIHSS)≤5)at presentation are common but often progress,leaving patients with significant disability.We compared the efficacy an...
National Natural Science Foundation of China(81870905,U20A20358,82111530203);Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(2019-I2M 5-029);The National Science and Technology Major Project(2017ZX09304018).
Background The benefit of intravenous alteplase in acute ischaemic stroke(AIS)is time-dependent.Tenecteplase is non-inferior to alteplase among patients with AIS.We aimed to delineate the association of the stroke ons...
To evaluate the clinical efficacy and safety of oral versus intravenous macrolide antibacterials in managing pediatric pneumonia attributable to Mycoplasma pneumoniae(MP),we conducted a retrospective analysis of clini...
supported by grants from the National Key Research and Development Program of China(2021YFA1101500);the National Natural Science Foundation of China(81974221,81974009,and 92049119);the Hubei Innovation Group Foundation(2022CFA019);the General Program of Health Commission of Hubei Province(WJ2023M126).
Mesenchymal stem cell-derived extracellular vesicles(MSC-EVs)have obvious advantages over MSC therapy.But the strong procoagulant properties of MSC-EVs pose a potential risk of thromboembolism,an issue that remains in...
Pain is the predominant symptom troubling patients.Pain management is one of the most important aspects in the management of surgical patients leading to early recovery from surgical procedures or in patients with chr...
supported by the Clinical Research Foundation of the National Health Commission of the People’s Republic of China(grant numbers:2022-GSP-GG-32,2022-GSP-QN-13 and 2023-GSP-QN-5).
Objective:Pulmonary hypertension is a crucial factor affecting the recovery after Glenn procedure.This study explores the effects of intravenous treprostinil on hemodynamic status and hospital postoperative recovery u...
The kidneys are complex organs responsible for waste removal and various regulatory functions.Critically ill patients often experience acute kidney injury(AKI).Although renal replacement therapy is used to manage AKI,...
Objective To investigate the clinical efficacy and safety of ferric derisomaltose injection versus iron sucrose injection in the treatment of iron deficiency anemia(IDA).Methods A total of 120 patients with iron defic...
HOPE is sponsored and supported by the Second Affiliated Hospital,School of Medicine,Zhejiang University.
Background While intravenous thrombolysis is recommended for patients who had an acute ischaemic stroke(AIS)within 4.5hours of symptom onset,there are few randomised trials investigating the benefits of thrombolysis b...