MACROLIDES

作品数:25被引量:36H指数:4
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相关领域:医药卫生更多>>
相关作者:王明贵张婴元施耀国张菁朱德妹更多>>
相关机构:复旦大学安徽医科大学附属省立医院中国农业大学更多>>
相关期刊:《Advances in Bioscience and Biotechnology》《Acta Pharmacologica Sinica》《Pharmacology & Pharmacy》《Chinese Medical Journal》更多>>
相关基金:国家自然科学基金广东省自然科学基金更多>>
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Diffuse panbronchiolitis in children misdiagnosed as asthma: A case report
《World Journal of Clinical Cases》2025年第14期44-50,共7页Anuvat Klubdaeng Prakarn Tovichien 
BACKGROUND Diffuse panbronchiolitis(DPB)is a rare,chronic inflammatory lung disease mar-ked by chronic cough,breathlessness,and preceding sinusitis.Symptoms often persist for years and can be misdiagnosed as asthma,pa...
关键词:ASTHMA BRONCHIOLITIS CHILDREN Diffuse panbronchiolitis MACROLIDES WHEEZE Case report 
Eutypetides A—E,Structurally Intriguing Polyketides Formed by Intramolecular[4+2]Cycloaddition from Marine-Derived Fungus Eutypella sp.F0219
《Chinese Journal of Chemistry》2025年第1期23-32,共10页Zhong-Ping Jiang Meng-Ting Chen Xiao Xiang Cong-Jun Xu Yong Rao Hong-Zhi Du Wan-Shan Li Ling Huang 
supported by the National Natural Science Foundation of China(82204275,82160653,and 22267006);Natural Science Foundation of Hainan Province(323Ms014 and 222QN303);Fundamental Research Funds for Hainan University(KYQD(ZR)-22088 and KYQD(ZR)-21089)。
Four polycyclic ten-membered lactones possessing unprecedented 10/6/5 tricyclic ring skeleton,named eutypetides A—D(1—4),and an intriguing polyketide containing a hexahydroisobenzofuran-1(3H)-one motif,named eutypet...
关键词:Marine-derived fungus Eutypella sp.F0219 POLYKETIDES Polycyclic macrolides [4+2]cycloaddition 
Occurrence,ecological,and health risk assessment of antibiotics in water from the Karst River during influenza season
《River》2024年第4期389-398,共10页Xiong Pan Wenjie Fu Yuyi Yang 
Knowledge Innovation Program of Wuhan-Shugung Project,Grant/Award Number:2023020201020363。
The widespread use of antibiotics has significantly increased their presence in aquatic environments,particularly in sensitive Karst River systems.In this study,the distribution and ecological,human health,and resista...
关键词:AZITHROMYCIN ecological risk Lijiang River MACROLIDES resistance selection risk 
Comparative efficacy of oral and intravenous macrolide antibiotics in treating pediatric pneumonia caused by Mycoplasma pneumoniae
《Journal of Chinese Pharmaceutical Sciences》2024年第12期1146-1152,共7页Lirong Qian Lina Gao 
To evaluate the clinical efficacy and safety of oral versus intravenous macrolide antibacterials in managing pediatric pneumonia attributable to Mycoplasma pneumoniae(MP),we conducted a retrospective analysis of clini...
关键词:Mycoplasma pneumoniae PNEUMONIA PEDIATRICS MACROLIDES ANTIBACTERIAL 
Acatulides A-G,neuroprotective macrolides from Acaulium album H-JQSF
《Chinese Chemical Letters》2024年第3期379-383,共5页Zhi-Wu Tong Ting-Ting Wang Pei Yang Jia-Lin Sun Chen-Peng Zhang Salman Khan Xin-Cun Wang Rui-Hua Jiao Hui-Ming Ge Wen-Ying Zhuang Gang Hu Ren Xiang Tan 
co-financed by the grants from National Nature Science Foundation of China(Nos.81991523 and 81991524);National Science and Technology Innovation 2030-Major Program of“Brain Science and Brain-Like Research”(No.2022ZD0211804)。
Fungal symbionts co-evolve with hosts and microbial co-inhabitants to acquire an unpredictable potential for producing novel bioactive metabolites,but the knowledge about the topic remains patchy and superficial.Here ...
关键词:Acaulium album MACROLIDES Acatulides A–G Mosher’s method NEUROPROTECTIVE 
Detections of mefA, ermB, and mphA Macrolides Resistant Genes in Bacteria Isolated from Covid-19 Patients from Selected Health Facilities in Ibadan, Nigeria
《Advances in Microbiology》2023年第2期106-117,共12页Florence Bamigbola Toyosi Raheem Muinat Fowora Felicia Adesina 
Background: COVID-19 is a disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Epidemiological data indicated that bacterial complications in COVID-19 would decrease clearance rate of the in...
关键词:SARS-CoV-2 Bacterial Co-Infection API 20E VITEK 2.0 and Resistant Genes 
Natural scaffolds-inspired synthesis of CF_(3)-substituted macrolides enabled by Rh-catalyzed C–H alkylation macrocyclization
《Chinese Chemical Letters》2022年第4期2015-2020,共6页Tongyu Bi Yi Xu Xin Xu Bixi Tang Qing Yang Yi Zang Zhenyang Lin Jia Li Weibo Yang 
the"100 Talent Program of Chinese Academy of Sciences";"1000-Youth Talents Plan";ShanghaiYouth Talent,National Science&Technology Major Project"Key New Drug Creation and Manufacturing Program"China(No. 2018ZX09711002–006);Science and Technology Commission of Shanghai Municipality (No. 18431907100);ShanghaiTechnology Innovation Action Plan (No. 18JC1415300);the Research Grants Council of Hong Kong (No. HKUST 16302418) for financial support of this research。
The development of innovative strategies and methods to provide natural product-like macrocycles not accessible by biosynthesis, but endowed with novel bioactivities and simplified structure, is highly desirable. Insp...
关键词:Rh-catalyzed C–H alkylation Late stage macrocyclization DFT calculation Anti-inflammation 
Lithocarpins E-G, Potent Anti-Tumor Tenellone-Macrolides from the Deep-Sea Fungus Phomopsis lithocarpus FS508
《Chinese Journal of Chemistry》2021年第5期1104-1112,共9页Jianlin Xu Yuchan Chen Zhaoming Liu Saini Li Yong Wang Yuhong Ren Hongxin Liu Weimin Zhang 
Guangdong Provincial Special Fund for Marine Economic Development Project([2020]042);the National Natural Science Foundation of China(41906106);the Guangdong Special Support Program(2019TQ05Y375);Team Project of the Natural Science Foundation of Guangdong Province(2016A030312014);the GDAS_Project of Science and Technology Development(2019GDASYL-0103007);We sincerely thank Mr.Can Li of central laboratory of Southern Medical University for NMR measurements.
Lithocarpins E-G,featuring a rare naturally-occurring highly oxygenated tenellone-macrolide skeleton,were isolated from the culture extract of a marine-derived fungus Phomopsis lithocarpus FS508.Their structures were ...
关键词:Phomopsis lithocarpus FS508 POLYKETIDES Structure elucidation Antitumor agents Apoptosis 
Clinical Evidence of Effective Therapy for Prostate Inflammation Based on a Combination of Macrolides and Men’s Pads
《Modern Research in Inflammation》2021年第1期1-9,共9页Edvard V. Kryzhanovskii Alexander B. Yavorsky Lim Kwong Choong 
Prostatitis is a widespread disease associated with pelvic pain syndrome, which is characterized by pelvic pain, various urinary symptoms, and possible sexual dysfunction. An adequate therapy requires schemes for chro...
关键词:PROSTATITIS Men’s Pad Combination Therapy 
Macrolide-Clarithromycin Task-Force for the Treatment and Prophylaxis of Covid-19 as a Single Agent
《Pharmacology & Pharmacy》2020年第6期85-104,共20页Eduardo Mansilla Ricardo Rangel Martínez Gustavo Horacio Marín Idiberto Zotarelli Filho Elsa Rivas Jaime Rivas Katherine Athayde Teixeira de Carvalho Mohammad Reza Dayer Alí Samadikuchaksaraei 
SARS-CoV-2 is a novel RNA coronavirus responsible of a deadly pandemic: the clinical illness COVID-19. With only one authorized drug for emergency use in critically ill patients: Remdesivir, there is not any other app...
关键词:COVID-19 MACROLIDES CLARITHROMYCIN Single Agent Therapy PROPHYLAXIS 
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