Occurrence,ecological,and health risk assessment of antibiotics in water from the Karst River during influenza season  

作　　者：Xiong Pan Wenjie Fu Yuyi Yang 

机构地区：[1]Basin Water Environmental Research Department,Changjiang River Scientific Research Institute,Wuhan,China [2]Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection(Guangxi Normal University),Ministry of Education,College of Environment and Resources,Guangxi Normal University,Guilin,China [3]Hubei Key Laboratory of Wetland Evolution&Ecological Restoration,Wuhan Botanical Garden,Chinese Academy of Sciences,Wuhan,China [4]Danjiangkou Wetland Ecosystem Field Scientific Observation and Research Station,The Chinese Academy of Sciences&Hubei Province,Wuhan,China [5]Key Laboratory of Lake and Watershed Science for Water Security,Nanjing Institute of Geography and Limnology,Chinese Academy of Sciences,Nanjing,China

出　　处：《River》2024年第4期389-398,共10页江河(英文)

基　　金：Knowledge Innovation Program of Wuhan-Shugung Project,Grant/Award Number:2023020201020363。

摘　　要：The widespread use of antibiotics has significantly increased their presence in aquatic environments,particularly in sensitive Karst River systems.In this study,the distribution and ecological,human health,and resistance selection risk assessment of 44 antibiotics in the typical Karst River,Lijiang River,were investigated during the influenza season,a period marked by heightened antibiotic usage.27 antibiotics could be found in the water of Lijiang River,among which azithromycin showing the highest concentrations.The concentrations of total antibiotics were in the range 171.70–2003.75 ng/L,with an average value of 704.76 ng/L.Macrolide was the predominant class,constituting an average of 57.65%of the total antibiotic concentrations.Risk assessments revealed that certain antibiotics,especially macrolides,posed moderate to high ecological risks to algae,displayed potential human health risks at low levels and contributed to antimicrobial resistance.Among all the antibiotics,azithromycin was the only one could cause ecological risk to algae,human health risk towards infants and antimicrobial resistance selection risk,which should be identified as the priority antibiotic for control in the Lijiang River during the influenza season.There was no difference in the concentrations,human health and antimicrobial resistance selection risk of antibiotics between mainstream and tributaries of Lijiang River.This study contributes to a better understanding of antibiotic pollution and provides insights into potential risk management practices in vulnerable aquatic systems worldwide.

关 键 词：AZITHROMYCIN ecological risk Lijiang River MACROLIDES resistance selection risk 

分 类 号：R73[医药卫生—肿瘤]