Supported by Natural Science Foundation of Hainan Province(820RC788).
Prostatitis is a common genitourinary disease characterized by a complex pathogenesis involving infection,inflammation,oxidative stress,and immune dysfunction.The p38MAPK signaling pathway plays a key role in inflamma...
National Major Scientific and the Technological Special Project:Establishment of a Clinically Oriented Preclinical Research and Development Technology Platform for New Chinese Medicines based on Famous Doctors'Prescriptions(No.2017ZX09301011);"Decoding Traditional Chinese Medicine"Project of Beijing University of Chinese Medicine:New Drugs Research and Development of Chinese Medicine based on Famous Doctors and Famous Prescriptions(No.90010961020020);the Horizontal Project:Preclinical Pharmacology and Pharmacodynamic Research of a New Chinese Medicine—Guilong Granules(No.2016110031007799)。
OBJECTIVE:To investigate the protective effects of Guilong prescription(归龙方,GL)on chronic prostatitis(CP)and unravel the underlying mechanisms of its pharmacological effects.METHODS:The composition of GL was determ...
supported by grants from the National Natural Science Foundation of China(No.PR0121015);the National Natural Science Foundation of China(No.82160148);the Natural Science Foundation Project of Gansu Province(No.2106RJZA110).
Recent evidence suggests that low-intensity extracorporeal shock wave therapy(Li-ESWT)is a promising treatment for chronic prostatitis/chronic pelvic pain syndrome(CP/CPPS);however,its safety in pelvic organs,particul...
Chronic prostatitis/chronic pelvic pain syndrome(CP/CPPS),also known as National Institutes of Health(NIH)type Ⅲ prostatitis,is a common disorder with an unclear etiology and no known curative treatments.Based on the...
Supported by the Natural Science Foundation of Shandong Province,No.ZR2021MH354.
BACKGROUND Bacille Calmette-Guérin(BCG)instillation is recommended in patients with nonmuscle-invasive bladder cancer who have intermediate-risk and high-risk tumors.However,granulomatous prostatitis is a rare compli...
Background: Prostatic abscesses are usually diagnosed in the setting of bacterial prostatitis. Rarely, they reveal or complicate granulomatous prostatitis (GP). Four cases of idiopathic xanthogranulomatous GP have bee...
The question of the impact of chronic prostatitis on male fertility remains debatable. In our study, we proved that inflammation of the prostate affects the characteristics of a man’s ejaculate. The inflammatory proc...
Supported by the National Natural Science Foundation of China (No.82104880);Scientific and Technological Innovation Project of China Academy of Chinese Medical Sciences (No.CI2021A02208);the Nursery Project of Xiyuan Hospital of China Academy of Chinese Medical Sciences (No.2019XYMP-23)。
Objective: To observe the efficacy and safety of Guihuang Formula(GHF) in treating patients with type Ⅲ prostatitis and Chinese medicine syndrome of dampness-heat and blood stasis. Methods: Sixty-six type Ⅲ prostati...
This work was supported by the National Natural Science Foundation of China(Grant No.81501245 and No.81971377);Fellowship of China Postdoctoral Science Foundation(Grant No.2020M671393);Jiangsu Province Postdoctoral Research Support Project(Grant No.2020Z134).
Experimental autoimmune prostatitis(EAP)-induced persistent inflammatory immune response can significantly upregulate the expression of N-methyl-D-aspartic acid(NMDA)receptors in the paraventricular nucleus(PVN).Howev...
BACKGROUND Prostatitis caused by Brucella infection is rare and usually lacks typical lower urinary tract symptoms.However,Brucella infection can cause serum prostatespecific antigen levels to become abnormally elevat...