Rare case of brucellosis misdiagnosed as prostate carcinoma with lumbar vertebra metastasis:A case report  

作　　者：Jun-Feng Yan Hai-Yong Zhou Sheng-Fu Luo Xing Wang Jian-Di Yu 

机构地区：[1]Department of Urology,Zhejiang Hospital,Hangzhou 310030,Zhejiang Province,China

出　　处：《World Journal of Clinical Cases》2021年第21期6009-6016,共8页世界临床病例杂志

摘　　要：BACKGROUND Prostatitis caused by Brucella infection is rare and usually lacks typical lower urinary tract symptoms.However,Brucella infection can cause serum prostatespecific antigen levels to become abnormally elevated.When concurrent with lumbar vertebra infection and erosion,brucellosis can easily be misdiagnosed as prostate cancer with bone metastasis.CASE SUMMARY A 45-year-old man complained of recurrent low back pain and fever for 2 wk.Magnetic resonance imaging of the lumbar vertebrae showed abnormal signs at the rear of the L4–5 vertebral body.Serum prostate-specific antigen level was 17.64 ng/mL,and positron emission tomography/computed tomography suggested the possibility of prostate cancer with liver and lumbar metastases.The patient was transferred to our department for further treatment.He experienced repeated bouts of fever and low back pain during hospitalization.Biopsy results indicated prostatitis.There was no significant increase in white blood cell count or procalcitonin levels.The Mycobacterium tuberculosis smear and antibody detection results were negative.Cefoperazone sulbactam was not effective.Blood culture test results were positive for brucellosis,confirming the diagnosis of brucellosis.After oral anti-infection treatment with doxycycline and rifampicin,the body temperature gradually returned to normal,and lumbago improved.After continuous treatment for 6 mo,the patient recovered.CONCLUSION In patients with low back pain and fever accompanied by elevated prostatespecific antigen levels and lesions of the prostate and lumbar spine,a detailed medical history and blood and urine cultures should be obtained,and attention should be given to the local epidemic infectious disease situation.

关 键 词：BRUCELLOSIS PROSTATITIS Infectious disease FEVER Prostate-specific antigen Case report 

分 类 号：R516.7[医药卫生—内科学]