云南高校图书馆联盟文献共享服务平台- MEDULLOBLASTOMA

MEDULLOBLASTOMA: 作品数：56被引量：80H指数：4; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：裴华东梁洁赵赋高敏娜李禄生更多>>; 相关机构：重庆医科大学北京市神经外科科研究所北京蛋白质组研究中心首都医科大学附属北京天坛医院更多>>; 相关期刊：《Chinese Medical Journal》《Signal Transduction and Targeted Therapy》《World Journal of Pediatrics》《World Journal of Emergency Medicine》更多>>; 相关基金：国家自然科学基金国家高技术研究发展计划瑞士科学基金湖北省自然科学基金更多>>

Single-cell transcriptomic sequencing identifies subcutaneous patient-derived xenograft recapitulated medulloblastoma: 《Animal Models and Experimental Medicine》2025年第3期458-472,共15页Jiayu Gao Yahui Zhao Ziwei Wang Fei Liu Xuan Chen Jialin Mo Yifei Jiang Yongqiang Liu Peiyi Tian Yanong Li Kaiwen Deng Xueling Qi Dongming Han Zijia Liu Zhengtao Yang Yixi Chen Yujie Tang Chunde Li Hailong Liu Jiankang Li Tao Jiang; National Key Research and Development Program of China,Grant/Award Number:2022ZD0210100;Beijing Nova Star Program,Grant/Award Number:2022002;Natural Science Foundation of Beijing and Haidian Collaboration Foundation,Grant/Award Number:L232079;National Natural Science Foundation of China,Grant/Award Number:82172608,82273343,81902975 and 82101356;Capital Medical University Fund for Excellent Young Scholars,Grant/Award Number:KCB2304。; Background:Medulloblastoma(MB)is one of the most common malignant brain tumors that mainly affect children.Various approaches have been used to model MB to facilitate investigating tumorigenesis.This study aims to com...; 关键词：experimental models MEDULLOBLASTOMA single-cell sequencing sPDX

Gut-brain axis:does intestinal inflammation affect hippocampal neurogenesis and medulloblastoma development?: 《Neural Regeneration Research》2023年第11期2381-2382,共2页Arianna Casciati Mariateresa Mancuso Roberta Vitali Simonetta Pazzaglia; NANOCROSS project"Plant virus nanoparticles for blood-brain barrier crossing and medulloblastoma targeting"granted by the Italian Association for Cancer Research:IG 20314 to MM。; Gut-brain axis:does intestinal inflammation affect hippocampal neurogenesis and medulloblastoma development?Inflammatory bowel diseases (IBD) are a group of disorders that cause chronic inflammation in the intestines,...; 关键词：inflammation DISEASES continuously

Sonic hedgehog signaling:Alternative splicing and pathogenic role in medulloblastoma被引量：2: 《Genes & Diseases》2023年第5期2013-2028,共16页Meiyu Qu Qiangqiang He Jiahao Luo Tingyu Shen Ruibo Gao Yana Xu Chengyun Xu Muhammad Qasim Barkat Ling-Hui Zeng Ximei Wu; supported by the National Natural Science Foundation of China(No.31571493,81741043,31871395,82000046,and 32170841).; Alternative splicing(AS)produces the different mRNA splicing bodies,which are then translated into multiple protein isoforms and participate in various biological functions.With a deeper understanding of alternative s...; 关键词：Alternative splicing EXON Hedgehog signaling MEDULLOBLASTOMA Tumor suppressor

CfDNA-based liquid biopsy of cerebrospinal fluid in medulloblastoma: 《Journal of Hainan Medical University》2023年第18期70-74,共5页FU Bing-biao ZHAO Ze-yu AN Si-long CHEN Hua-shuai ZHAO Jian-nong; Key Social Development Project in Hainan Province(No.ZDYF2019173)。; Medulloblastoma(MB)is the most common childhood embryonal malignant tumour in the central nervous system.The diagnosis,prognosis and therapeutic targets of MB depend on the molecular characteristics of the tumor,and i...; 关键词：MEDULLOBLASTOMA Liquid biopsy of cerebrospinal fluid cfDNA

Deep Learning Framework for the Prediction of Childhood Medulloblastoma: 《Computer Systems Science & Engineering》2023年第7期735-747,共13页M.Muthalakshmi T.Merlin Inbamalar C.Chandravathi K.Saravanan; This research work develops new and better prognostic markers for predicting Childhood MedulloBlastoma(CMB)using a well-defined deep learning architecture.A deep learning architecture could be designed using ideas fro...; 关键词：Brain tumour childhood medulloblastoma deep learning histopathological images medical image analysis

Analysis of the personalized treatment and the relevant prognostic factors in children with medulloblastoma: 《BIOCELL》2023年第5期1065-1073,共9页LIHUA CHEN HONGTIAN ZHANG YONG XIA KAI SUN WENJIN CHEN RUXIANG XU; funded by the Key Research and Development Project of the Science and Technology Department of Sichuan Province(No.2021YFS0010).; Purpose:The present study summarized cases of children(n=32)with medulloblastoma(MB)who were treated using stratified therapy based on risk grading and also discussed the factors affecting prognosis.Methods:According ...; 关键词：Medulloblastoma in children Risk stratification Individualized therapy Prognostic influencing factor

Immune microenvironment of medulloblastoma:The association between its molecular subgroups and potential targeted immunotherapeutic receptors: 《World Journal of Clinical Oncology》2023年第3期117-130,共14页Maher Kurdi Nasser Mulla Husam Malibary Ahmed K Bamaga Motaz M Fadul Eyad Faizo Sahar Hakamy Saleh Baeesa; Medulloblastoma(MB)is considered the commonest malignant brain tumor in children.Multimodal treatments consisting of surgery,radiation,and chemotherapy have improved patients’survival.Nevertheless,the recurrence occu...; 关键词：MEDULLOBLASTOMA Tumour microenvironment Tumour associated macrophages Tumour infiltrating lymphocyte IMMUNOTHERAPIES

Microsurgical Resection of Cerebellopontine Angle Medulloblastoma, Case Report and Review of Literature: 《Open Journal of Modern Neurosurgery》2022年第4期175-180,共6页Fadal Alretimi Hesham Ben Khayal Abdussalam Abograra Said Lubna Azzouz Amani Masoud; Cerebellopontine angle (CPA) medulloblastomas (MB) are rare lesions with few cases previously described in the literature. We report one more case of CPA MB. The patient was a (36)-year-old female with a mass developi...; 关键词：MEDULLOBLASTOMA Extra-Axial Cerebello-Pontine (CP) Angle

Metabolic determinants of stemness in medulloblastoma: 《World Journal of Stem Cells》2022年第8期587-598,共12页Paula Martín-Rubio Pilar Espiau-Romera Alba Royo-García Laia Caja Patricia Sancho; Supported by the Miguel Servet and pFIS fellowships,No.CP16/00121(P.S.) and No.FI21/00031(P.E-R.) from the Instituto de Salud Carlos Ⅲ and cofinanced by European funds(FSE:“el FSE invierte en tu futuro”);Magnus Bergvalls Stiftelse,No.2021-04284(L.C.);the Ⅳ Grant for Childhood Cancer Research from Asociación de Padres de Niños con Cáncer de Aragón(ASPANOA,P.S.).; Medulloblastomas(MBs)are the most prevalent brain tumours in children.They are classified as grade IV,the highest in malignancy,with about 30%metastatic tumours at the time of diagnosis.Cancer stem cells(CSCs)are a sm...; 关键词：MEDULLOBLASTOMA Cancer stem cells STEMNESS METABOLISM GLYCOLYSIS LIPIDS

Liposomal Honokiol induces ROS-mediated apoptosis via regulation of ERK/p38-MAPK signaling and autophagic inhibition in human medulloblastoma被引量：4: 《Signal Transduction and Targeted Therapy》2022年第3期625-627,共3页Shenglan Li Jinyi Chen Yaqiong Fan Ce Wang Can Wang Xiaohong Zheng Feng Chen Wenbin Li; This study was funded by the National Natural Science Foundation of China(No.81972338);Clinical Major Specialty Projects of Beijing(2-1-2-038).; Dear Editor,Nowadays,medulloblastoma accounts for approximately 25% of all pediatric brain tumors.1 Even with the successful treatment of primary tumors,there are still serious side effects.Honokiol(HNK)is defined as ...; 关键词：TUMORS pediatric LIPO

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