LIPO

作品数:108被引量:208H指数:7
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相关领域:医药卫生更多>>
相关作者:王忠富任守凤文立戴炯李善泉更多>>
相关机构:索尔维公司苏州大学临沂市中医医院湖南农业大学更多>>
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相关基金:国家自然科学基金江西省自然科学基金北京市自然科学基金浙江省自然科学基金更多>>
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Deciphering the molecular basis of lipoprotein recognition and transport by LolCDE
《Signal Transduction and Targeted Therapy》2025年第1期434-445,共12页Wen Qiao Chongrong Shen Yujiao Chen Shenghai Chang Xin Wang Lili Yang Jie Pang Qinghua Luo Zhibo Zhang Yingxin Xiang Chao Zhao Guangwen Lu Bi-Sen Ding Binwu Ying Xiaodi Tang Haohao Dong 
supported by the National Key Research and Development Program of China(2021YFA1301900 to H.D.);the National Natural Science Foundation of China(31900039 and 32170029 to X.T.,32000844 to S.C.,81971974 and 82372297 to H.D.);the 1.3.5 Project for Disciplines Excellence of West China Hospital,Sichuan University(ZYYC23014 to H.D.);the Sichuan Provincial Natural Science Foundation Outstanding Young Scientist Fund Project(2024NSFJQ0002 to H.D.).
Outer membrane(OM)lipoproteins serve vital roles in Gram-negative bacteria,contributing to their pathogenicity and drug resistance.For these lipoproteins to function,they must be transported from the inner membrane(IM...
关键词:FUNCTIONS OUTSIDE CHAINS 
Emerging Sialylated Class R Lipooligosaccharides in Campylobacter jejuni from Seagulls Has the Potential to Trigger Guillain-BarréSyndrome—Yunnan Province,China,2018–2023
《China CDC weekly》2024年第45期1177-1182,共6页Xiaoli Chen Yixin Gu Hairui Wang Guilan Zhou Xin Zhang Chang Liu Zhujun Shao Jianzhong Zhang Maojun Zhang 
Supported by National Key Research and Development Program of China(2021YFC2301000);Research on detection and tracing of important pathogen combinations,identification and prevention of drug resistance hazards(SZSM201803081);Project for Gonorrhea vaccine development(2023110024000074).
What is already known about this topic?Lipooligosaccharides from Campylobacter jejuni(C.jejuni)have a mimicry antigen structure with gangliosides,which explains the mechanism by which C.jejuni caused Guillain-Barrésy...
关键词:COASTAL OLIGOSACCHARIDES LIPO 
Long-chain acyl-CoA synthetase regulates systemic lipid homeostasis via glycosylation-dependent lipoprotein production
《Life Metabolism》2024年第2期38-54,共17页Jie Li Yue Dong Tianxing Zhou He Tian Xiahe Huang Yong Q.Zhang Yingchun Wang Sin Man Lam Guanghou Shui 
supported by grants from the National Natural Science Foundation of China(92057202 and 31871194);the National Key R&D Program of China(2018YFA0506900 and 2018YFA0800901).
Interorgan lipid transport is crucial for organism development and the maintenance of physiological function.Here,we demonstrate that Drosophila long-chain acyl-CoA synthetase(dAcsl),which catalyzes the conversion of ...
关键词:lipid homeostasis APOLIPOPROTEIN GLYCOSYLATION LIPIDOMICS metabolomics proteomics 
Bi-doped carbon quantum dots functionalized liposomes with fluorescence visualization imaging for tumor diagnosis and treatment
《Chinese Chemical Letters》2024年第4期414-419,共6页Peide Zhu Yangjia Liu Yaoyao Tang Siqi Zhu Xinyang Liu Lei Yin Quan Liu Zhiqiang Yu Quan Xu Dixian Luo Juncheng Wang 
funded by Beijing Natural Science Foundation (Nos.L222109, 3222018);Military Health Care Project(No.22BJZ22);Science Foundation of China University of Petroleum (Nos.2462019QNXZ02, 2462019BJRC007);National Natural Science Foundation of China (Nos.52211530034, 82273236);Guangdong Provincial Basic and Applied Basic Research Foundation (Nos.2022A151522004, 2022A1515220042);Science and Technology Innovation Commission of Shenzhen (Nos.JSGG20210802153410031, JCYJ20220530141609021);Science and Technology Plan of Shenzhen Nanshan District (No.NS016);Discipline Leader Foundation of Huazhong University of Science and Technology Union Shenzhen Hospital (No.YN2021002);Crosswise Project of Daan Gene (No.HXKY2022002)。
Liposomes are one of the significant classes of antitumor nanomaterials and the most successful nanomedicine drugs in clinical translation. However, it is difficult to accurately reveal liposome delivery modes and dru...
关键词:Bi-doped CQDs Lipo/Bi-doped CQDs pH sensitivity In vitro/in vivo imaging Diagnosis and treatment integration 
Concise Synthesis of Lactococcus garvieae Lipoteichoic Acids Through an Additive-Modulated Preactivation Protocol and the Immunological Studies
《CCS Chemistry》2024年第2期403-414,共12页Tianlu Li Tong Li Yue Yang Haoru Zhuang Jianwu Lv Ning Zhou Miaomiao Zhang Fengshan Wang Yiqun Geng Richard R.Schmidt Peng Peng 
supported by the National Natural Science Foundation of China(grant nos.21977063,92053110,and 22177061);the National Key Research and Development Program of China(grant no.2018YFA0902000);the China Postdoctoral Science Foundation(grant no.2020M680090);the Qilu Youth Scholar Program of Shandong University,the Central Government Guide Local Science and Technology Development Funds(grant no.YDZX20203700002579);the Nonprofit Central Research Institute Fund of Chinese Academy of Medical Sciences(grant no.2021-RC350-002);the CAMS Innovation Fund for Medical Sciences(CIFMS)(grant no.2021-1-I2M-026).
Lipoteichoic acids(LTAs)are macroamphiphiles composed of alditol,lipid,phosphate,and carbohydrate units.Due to their inherent complexity,it is a severe challenge to access LTAs with structural integrity from natural s...
关键词:1 2-cis glycosidation STEREOSELECTIVITY lipoteichoic acid total synthesis additive-modulated trichloroacetimidate glycosidation immune response 
Comparison of the effects of 3 kinds of oils rich in omega-3 polyunsaturated fatty acids on glycolipid metabolism and lipoprotein subfractions被引量:1
《Food Science and Human Wellness》2023年第6期2221-2231,共11页Hechun Liu Feng Wang Hui Xia Da Pan Ligang Yang Shaokang Wang Feng Zhao Guiju Sun 
supported by the two National Natural Science Foundations of China(81872618 and 81573144).
Dietary omega-3 polyunsaturated fatty acids(ω-3 PUFAs)can be classifi ed into animal-and plant-derivedω-3 PUFAs.Patients with type 2 diabetes(T2DM)are frequently accompanied by dyslipidemia,which is closely related ...
关键词:Diabetes Omega-3 polyunsaturated fatty acid Lipoprotein subfraction DYSLIPIDEMIA 
CSB1-Lipo-DOX-miR101靶向治疗乳腺癌及抗耐药效应的体外研究
《陕西师范大学学报(自然科学版)》2023年第3期53-64,共12页陈利荣 贾晨霜 冯洋 赵瑞霞 赵雪薇 徐婕 舒展 侯颖春 
陕西省自然科学基金(2022JQ-219)。
通过薄膜超声分散技术、硫酸铵主动载药技术构建了靶向乳腺癌(breast cancer,BC)细胞的具有抑制化疗药物多药耐药性(multidrug resistance,MDR)特征的阿霉素(doxorubicin,DOX)脂质体载药体系CSB1-Lipo-DOX-miR101。应用MTT法、损伤修复...
关键词:乳腺癌 阿霉素 脂质体 靶向药物递送 多药耐药性(MDR) 靶向多肽 miRNA101 
Lipo-nutritional quality of pork:The lipid composition,regulation,and molecular mechanisms of fatty acid deposition被引量:3
《Animal Nutrition》2023年第2期373-385,共13页Wuzhou Yi Qixin Huang Yizhen Wang Tizhong Shan 
supported by the Natural Science Foundation of Zhejiang Province(LZ22C170003);the Zhejiang Provincial Key R&D Program of China(2021C02008);the Fundamental Research Funds for the Central University(226-2022-00113),and the“Hundred Talents Program”funding from Zhejiang University to TZS.
Pork is one of the main meats consumed by people,and its nutritional value is closely related to human health.The lipid deposition and composition of pork not only affect the sensory quality but also determine the nut...
关键词:Fatty acid composition Intramuscular fat Dietary factor Gut microbiota Non-coding RNA 
Alpha lipoamide inhibits diabetic kidney fibrosis via improving mitochondrial function and regulating RXRα expression and activation被引量:1
《Acta Pharmacologica Sinica》2023年第5期1051-1065,共15页Hui-fang Zhang Hui-ming Liu Jia-yi Xiang Xing-cheng Zhou Dan Wang Rong-yu Chen Wan-lin Tan Lu-qun Liang Ling-ling Liu Ming-jun Shi Fan Zhang Ying Xiao Yu-xia Zhou Tian Zhang Lei Tang Bing Guo Yuan-yuan Wang 
supported by the National Natural Science Foundation of China(82060141,81960141);Merit-based Funding for High-level Talent Innovation and Entrepreneurship in Guizhou Province[(2021)02];Science and Technology Top Talent Project of General Higher Education Institutions in Guizhou Province(Qianjiaohe KY[2021]032).
Previous studies have shown mitochondrial dysfunction in various acute kidney injuries and chronic kidney diseases.Lipoic acid exerts potent effects on oxidant stress and modulation of mitochondrial function in damage...
关键词:diabetic kidney disease alpha lipoamide mitochondria RXRα CDX2 tubulointerstitial fibrosis 
Fat grafting in autologous breast reconstruction:applications,outcomes,safety,and complications
《Plastic and Aesthetic Research》2023年第1期485-500,共16页Bahaa Shaaban David Guerrero Carolyn De La Cruz Lauren Kokai 
Autologous fat grafting is an important surgical technique in aesthetic and reconstructive procedures.Fat grafting for breast reconstruction is now an established procedure for adding volume and improving cutaneous pl...
关键词:Fat grafting fat transfer autologous breast reconstruction implant reconstruction lipo-injection breast augmentation graft survival skin expansion MASTECTOMY post-mastectomy pain breast fibrosis capsular contracture 
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