APOLIPOPROTEIN

作品数：107被引量：259H指数：9
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A natural nano-platform:Advances in drug delivery system with recombinant high-density lipoprotein
《Chinese Chemical Letters》2024年第11期74-86,共13页Zhilong Xie Guohui Zhang Ya Meng Yefei Tong Jian Deng Honghui Li Qingqing Ma Shisong Han Wenjun Ni 
the National Natural Science Foundation of China(Nos.52273128,82003450);the Natural Science Foundation of Guangdong Province(No.2022A1515220048);the Natural Science Foundation of Guizhou Province(Nos.Guizhou Province-ZK[2022]General 300,Guizhou Province-ZK[2023]General 244);the Xiangshan Talented Scientific Research Foundation of Zhuhai People’s Hospital(No.2023XSYC-01);Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment(No.2021B1212040004)。
Developing natural nano-platforms with high biocompatibility and natural targeting ability represents great significance for drug delivery.High-density lipoprotein(HDL),a natural lipid-protein complex,plays important ...
关键词：High-density lipoproteins Drug delivery APOLIPOPROTEIN Targeting mechanisms HDL nanoparticle preparation Cardiovascular disease Cancer treatment 
Author Correction:Apolipoprotein C1 promotes glioblastoma tumorigenesis by reducing KEAP1/NRF2 and CBS-regulated ferroptosis被引量：1
《Acta Pharmacologica Sinica》2024年第10期2226-2227,共2页Xiang-jin Zheng Wen-lin Chen Jie Yi Wan Li Jin-yi Liu Wei-qi Fu Li-wen Ren Sha Li Bin-bin Ge Yi-hui Yang Yi-zhi Zhang Hong Yang Guan-hua Du Yu Wang Jin-hua Wang 
Correction to:Acta Pharmacologica Sinica https://doi.org/10.1038/s41401-022-00917-3,published online 17 May 2022 The authors are very sorry for the inadvertent mistake in the Figure 4:the images of intracellular Fe^(2...
关键词：Figure CBS MISTAKE 
Associations between physical activity levels and ATPase inhibitory factor 1 concentrations in older adults
《Journal of Sport and Health Science》2024年第3期409-418,共10页Jérémy Raffin Yves Rolland Annelise Genoux Guillaume Combes Mikael Croyal Bertrand Perret Sophie Guyonnet Bruno Vellas Laurent O.Martinez Philipe de Souto Barreto For the MAPT/DSA Group 
supported by grants from the Region Occitanie/Pyrénées-Méditerranée(Grant No.1901175);the European Regional Development Fund(ERDF)(Grant No.MP0022856);This study received funding from la Fédération Française de Cardiologie”(FFC,Dotation Recherche),Alzheimer Prevention in Occitania and Catalonia(APOC Chair of Excellence-Inspire Program);Saint Louis University.The MAPT study was supported by grants from the Gérontopôle of Toulouse,the French Ministry of Health(PHRC 2008,2009);Pierre Fabre Research Institute(manufacturer of the omega-3 supplement);ExonHit Therapeutics SA,and Avid Radiopharmaceuticals,Inc.The promotion of this study was supported by the University Hospital Center of Toulouse;The data-sharing activity was supported by the Association Monegasque pour la Recherche sur la Maladie d'Alzheimer(AMPA)and the INSERM-University of Toulouse III UMR 1295(CERPOP)Research Unit.
Background:Adenosine triphosphatase inhibitory factor 1(IF1)is a key protein involved in energy metabolism.IF1 has been linked to various agerelated diseases,although its relationship with physical activity(PA)remains...
关键词：Aging APOLIPOPROTEIN BIOENERGETICS Exerkine MITOCHONDRIA 
Long-chain acyl-CoA synthetase regulates systemic lipid homeostasis via glycosylation-dependent lipoprotein production
《Life Metabolism》2024年第2期38-54,共17页Jie Li Yue Dong Tianxing Zhou He Tian Xiahe Huang Yong Q.Zhang Yingchun Wang Sin Man Lam Guanghou Shui 
supported by grants from the National Natural Science Foundation of China(92057202 and 31871194);the National Key R&D Program of China(2018YFA0506900 and 2018YFA0800901).
Interorgan lipid transport is crucial for organism development and the maintenance of physiological function.Here,we demonstrate that Drosophila long-chain acyl-CoA synthetase(dAcsl),which catalyzes the conversion of ...
关键词：lipid homeostasis APOLIPOPROTEIN GLYCOSYLATION LIPIDOMICS metabolomics proteomics 
Alzheimer’s Disease Aβ-Amyloid Plaque Morphology Varies According to APOE Isotype
《World Journal of Neuroscience》2023年第3期118-133,共16页Ina Caesar K. Peter R. Nilsson Per Hammarström Mikael Lindgren Stefan Prokop James Schmeidler Vahram Haroutunian David M. Holtzman Patrick R. Hof Sam Gandy 
Background: The apolipoprotein E (APOE, gene;apoE, protein) ε4 allele is the most commonly identified genetic risk factor for typical late-onset sporadic Alzheimer’s disease (AD). Each APOE ε4 allele roughly triple...
关键词：Alzheimer’s Disease AMYLOID APOLIPOPROTEIN Luminescent Conjugated Oligothiophenes Hyperspectral Separation 
Apolipoprotein C1 promotes tumor progression in gastric cancer
《Oncology Research》2023年第3期287-297,共11页QIOU GU TIAN ZHAN XIAO GUAN CHUILIN LAI NA LU GUOGUANG WANG LEI XU XIANG GAO JIANPING ZHANG 
financed by the National Natural Science Foundation(Grant Number 81874058 to Jianping Zhang).
Background:Gastric cancer(GC)is a malignancy with the worst prognosis that seriously threatens human health,especially in East Asia.Apolipoprotein C1(apoc1)belongs to the apolipoprotein family.In addition,apoc1 has be...
关键词：Gastric cancer Apolipoprotein C1 TME Immune cell infiltration Drug sensitivity 
CYP2C19、APOE基因在慢性血管疾病中的表征及其与抗血小板药物研究进展被引量：1
《亚洲心脑血管病例研究》2023年第1期1-8,共8页赖腾芳 李近都 梁烨 李世龙 李天资 
研究背景:研究证实阿司匹林对控制慢性血管疾病进展有显著效果,抗血小板药物应运而生。目前状况:抗血小板药物成为防治老年慢性疾病(chronic diseases of old age)不能或缺的常规性辅助治疗方案,阿司匹林、氯吡格雷、华法林、地奥斯明...
关键词：慢性血管疾病 CYP2C19 APOLIPOPROTEIN 基因突变 抗血小板药物 治疗反应 
Progress in the Study of the Correlation between Apolipoproteins and Endometrial Cancer被引量：1
《Journal of Biosciences and Medicines》2022年第12期110-121,共12页Luqing Lou Haibin Zhu 
In recent years, Lipid metabolism disorder has been closely related to malignant tumors. Apolipoprotein (Apo), as an important protein in lipoprotein transport and metabolism, plays an important role in the process of...
关键词：Endometrial Carcinoma APOLIPOPROTEIN CARCINOGENESIS 
Apolipoprotein C1 promotes glioblastoma tumorigenesis by reducing KEAP1/NRF2 and CBS-regulated ferroptosis被引量：2
《Acta Pharmacologica Sinica》2022年第11期2977-2992,共16页Xiang-jin Zheng Wen-lin Chen Jie Yi Wan Li Jin-yi Liu Wei-qi Fu Li-wen Ren Sha Li Bin-bin Ge Yi-hui Yang Yi-zhi Zhang Hong Yang Guan-hua Du Yu Wang Jin-hua Wang 
Bejing Natural Science Foundation(7212157);CAMS Innovation Fund for Medical Sciences(2021-12M-1-029);National Natural Science Foundation of China(81703536,81803584,81703565);Technology Major Projects for“Major New Drugs Innovation and Development”(2018ZX09711001-005-025,2018ZX09711001-012);Peking Union Medical College Graduate Innovation Fund(2019-1007-07).
Glioblastoma(GBM),a malignant brain tumor,is a world-wide health problem because of its poor prognosis and high rates of recurrence and mortality.Apolipoprotein C1(APOC1)is the smallest of apolipoproteins,implicated i...
关键词：GLIOBLASTOMA TUMORIGENESIS APOC1 ferroptosis lipid ROS NRF2 CBS 
Author Correction:Apolipoprotein C1 promotes glioblastoma tumorigenesis by reducing KEAP1/NRF2 and CBS-regulated ferroptosis
《Acta Pharmacologica Sinica》2022年第11期3011-3012,共2页Xiang-jin Zheng Wen-lin Chen Jie Yi Wan Li Jin-yi Liu Wei-qi Fu Li-wen Ren Sha Li Bin-bin Ge Yi-hui Yang Yi-zhi Zhang Hong Yang Guan-hua Du Yu Wang Jin-hua Wang 
During our recent check of our published article entitled“Apolipoprotein C1 promotes glioblastoma tumorigenesis by reducing KEAP1/NRF2 and CBS-regulated ferroptosis”in Acta Pharmacologica Sinica,we found that there ...
关键词：journal APOLIPOPROTEIN GLIOBLASTOMA 
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