supported by the National Natural Science Foundation of China(grant number 81773285);Beijing Chao-Yang Hospital Golden Seeds Foundation(grant number CYJZ202341).
Osteosarcoma(OS)is a prevalent primary bone malignancy with limited treatment options.Therefore,it is imperative to investigate and understand the mechanisms underlying OS pathogenesis.Cancer-associated fibroblasts(CA...
supported by the National Natural Science Foundation of China(82103298);Basic Research Project of Science and Technology Cooperation in Qiandongnan Prefecture(No.2023-16).
Circular RNAs(circRNAs)are a type of non coding RNA that possess unique single stranded circular structures formed through reverse splicing mechanisms.Due to the lack of a free end that is typically susceptible to deg...
supported by the Natural Science Foundation of Hunan Province(No.2021JJ30589);Hunan Provincial Natural Science Foundation Sector Joint Fund(No.2023JJ60049).
Approximately half of all cancers have p53 inactivating mutations,in addition to which most malignancies inactivate the p53 pathway by increasing p53 inhibitors,decreasing p53 activators,or inactivating p53 downstream...
Objective:To evaluate the value of rehabilitation nursing based on mind mapping model combined with psychological intervention for patients with nephrotic syndrome(NS).Methods:A total of 60 patients with NS who visite...
supported by the National Natural Science Foundation of China under grant 82103397 to Y.L.;R&D Program of Zhejiang Province under grant 2024C03142 to L.Z.
Golgi protein 73(GP73),a resident protein of the Golgi apparatus,is notably elevated in hepatocellular carcinoma(HCC).While its critical role in remodeling the tumor microenvironment(TME)is recognized,the intricate me...
supported by the grants from the National Natural Science Foundation of China(Nos.82171074,81970809 and 81570859);the Suzhou Medical Innovation Application Research Project(No.SZM2023027).
Transcription factor 3(TCF3),a pivotal member of the TCF/LEF family,plays a critical role in tumorigenesis.Nonetheless,its impact on the tumor microenvironment(TME)and cancer phenotypes remains elusive.We perform an e...
Nanotechnology in cancer therapy has significantly advanced treatment precision,effectiveness,and safety,improving patient outcomes and personalized care.Engineered smart nanoparticles and cell-based therapies are des...