TME

作品数:461被引量:1533H指数:18
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相关领域:医药卫生更多>>
相关作者:周总光池畔张忠涛杜燕夫李振军更多>>
相关机构:福建医科大学四川大学华西医院吉林大学扬州大学更多>>
相关期刊:更多>>
相关基金:国家自然科学基金北京市自然科学基金陕西省科技攻关计划广东省自然科学基金更多>>
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Research progress on cancer-associated fibroblasts in osteosarcoma
《Oncology Research》2025年第5期1091-1103,共13页LIWEN FENG YUTING CHEN WENYI JIN 
supported by the National Natural Science Foundation of China(grant number 81773285);Beijing Chao-Yang Hospital Golden Seeds Foundation(grant number CYJZ202341).
Osteosarcoma(OS)is a prevalent primary bone malignancy with limited treatment options.Therefore,it is imperative to investigate and understand the mechanisms underlying OS pathogenesis.Cancer-associated fibroblasts(CA...
关键词:Osteosarcoma(OS) Cancer-associated fibroblasts(CAFs) Tumor microenvironment(TME) Bone tumor 
Immunomodulatory behavior of CircRNAs in tumor microenvironment
《Oncology Research》2025年第5期1105-1119,共15页HAISU LIANG WEI YAN ZHI LIU YUNBO HE JIAO HU ZHIWEI SHU HUIHUANG LI BELAYDI OTHMANE WENBIAO REN CHAO QUAN DONGXU QIU MINFENG CHEN WEI XIONG BINGNAN ZHANG PEIHUA LIU 
supported by the National Natural Science Foundation of China(82103298);Basic Research Project of Science and Technology Cooperation in Qiandongnan Prefecture(No.2023-16).
Circular RNAs(circRNAs)are a type of non coding RNA that possess unique single stranded circular structures formed through reverse splicing mechanisms.Due to the lack of a free end that is typically susceptible to deg...
关键词:Circular RNA(circRNA) Immune response Metabolic reprogramming TUMOR Tumor microenvironment(TME) 
p53:A player in the tumor microenvironment
《Oncology Research》2025年第4期795-810,共16页SHUANG ZHAO HONGYONG WEN BAIQI WANG QINGLIN XIONG LANXIN LI AILAN CHENG 
supported by the Natural Science Foundation of Hunan Province(No.2021JJ30589);Hunan Provincial Natural Science Foundation Sector Joint Fund(No.2023JJ60049).
Approximately half of all cancers have p53 inactivating mutations,in addition to which most malignancies inactivate the p53 pathway by increasing p53 inhibitors,decreasing p53 activators,or inactivating p53 downstream...
关键词:Tumor microenvironment(TME) P53 Wild type p53 Mutant p53 Cancer therapy 
网络演唱会品牌TME live的创新策略与发展前景
《中国集体经济》2025年第12期153-156,共4页裴斐 
近年来,粉丝经济愈发成为文娱产业中不容忽视的力量。在疫情对线下演唱会、粉丝见面活动的全面冲击下,腾讯音乐旗下线上演唱会厂牌TME live顺势而起。通过定制化超现场、高品质视觉呈现与隔空互动的创新性玩法,将线下演唱会转上云端,为...
关键词:线上演唱会 TME live 数字音乐 粉丝经济 创新策略 
Effects of Rehabilitation Nursing Combined with Psychological Intervention Based on Mind Mapping Model on Emotional State and Treatment Compliance of Patients with Nephrotic Syndrome
《Journal of Clinical and Nursing Research》2025年第3期64-69,共6页Xiuju Huang Juan Zhang 
Objective:To evaluate the value of rehabilitation nursing based on mind mapping model combined with psychological intervention for patients with nephrotic syndrome(NS).Methods:A total of 60 patients with NS who visite...
关键词:Nephrotic syndrome Psychological intervention Mind mapping model Rehabilitation nursing 
Golgi Protein 73 Promotes Angiogenesis in Hepatocellular Carcinoma
《Research》2025年第1期739-751,共13页Yiming Liu Xinyang Hu Sining Zhou Ting Sun Feiyan Shen Linghui Zeng 
supported by the National Natural Science Foundation of China under grant 82103397 to Y.L.;R&D Program of Zhejiang Province under grant 2024C03142 to L.Z.
Golgi protein 73(GP73),a resident protein of the Golgi apparatus,is notably elevated in hepatocellular carcinoma(HCC).While its critical role in remodeling the tumor microenvironment(TME)is recognized,the intricate me...
关键词:golgi apparatusis remodeling tumor microenvironment tme ANGIOGENESIS hepatocellular carcinoma prolyl hydroxylase golgi protein 
T细胞耗竭在肝细胞癌患者免疫治疗中的研究进展
《细胞与分子免疫学杂志》2025年第3期271-277,共7页伍杨 李甜 张润兵 张亚妮 朱玲玲 史婷婷 王顺娜 杨妹霞 于晓辉 张久聪 
甘肃省科技计划项目(21R7RA017);甘肃省卫生健康行业科研计划项目(GSWSKY2023-34);兰州市科技计划项目(2023-2-29);甘肃中医药大学导师专项(2023YXKY020)。
肝细胞癌(HCC)是全球发病率增长速度最快的癌症之一,在全球癌症致死原因中位列第四。当前HCC治疗领域发展迅猛,免疫治疗已被公认为是一种极具前景的治疗手段,其中T细胞在HCC免疫治疗中发挥着关键作用。然而,在病毒感染情形下或身处肿瘤...
关键词:T细胞耗竭(Tex) 肝细胞癌(HCC) 免疫治疗 肿瘤微环境(TME) 综述 
TCF3 as a multidimensional biomarker:oncogenicity,genomic alterations,and immune landscape in pan-cancer analysis
《Acta Biochimica et Biophysica Sinica》2025年第2期195-208,共14页Huiling Nie Yang Yu Siqi Zhou Yue Xu Xi Chen Xun Qin Zhangyu Liu Jiayu Huang Hailiang Zhang Jin Yao Qin Jiang Bingbing Wei Xiaojian Qin 
supported by the grants from the National Natural Science Foundation of China(Nos.82171074,81970809 and 81570859);the Suzhou Medical Innovation Application Research Project(No.SZM2023027).
Transcription factor 3(TCF3),a pivotal member of the TCF/LEF family,plays a critical role in tumorigenesis.Nonetheless,its impact on the tumor microenvironment(TME)and cancer phenotypes remains elusive.We perform an e...
关键词:TCF/LEF family TCF3 pan-cancer analysis prognosis tumor microenvironment(TME) epithelial-mesenchymal transition(EMT) 
响应型纳米载体递送药物用于癌症治疗的研究进展
《上海师范大学学报(自然科学版中英文)》2025年第1期74-83,共10页祝清云 苏丹阳 陈楠 
国家自然科学基金(21974089)。
近年来,纳米载体因其优异的负载能力、高效的递送性能以及精准的靶向性,在药物及功能性核酸的递送领域受到了广泛关注.这些特性使纳米载体能够将药物或核酸直接输送至病变区域,为癌症治疗提供了新的策略.为了降低纳米药物对正常组织的...
关键词:刺激响应型纳米载体 肿瘤微环境(TME) 癌症治疗 协同治疗 
Research advancements in nanoparticles and cell-based drug delivery systems for the targeted killing of cancer cells
《Oncology Research》2025年第1期27-44,共18页MERYEM A.ABDESSALEM SIRIN A.ADHAM 
Nanotechnology in cancer therapy has significantly advanced treatment precision,effectiveness,and safety,improving patient outcomes and personalized care.Engineered smart nanoparticles and cell-based therapies are des...
关键词:Drug delivery Cancer NANOPARTICLES Liposomes Micelles Combination therapies Targeted therapy Precision medicine Tumor microenvironment(TME) 
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