supported by National Health and Medical Research Council GNT1105374,GNT1137645,GNT2000766 and veski Innovation Fellowship(VIF23)to RP.
Nuclear factor Y is a ubiquitous heterotrimeric transcription factor complex conserved across eukaryotes that binds to CCAAT boxes,one of the most common motifs found in gene promoters and enhancers.Over the last 30 y...
supported by the National Key Research and Development Program of China(2022YFA1105304);the National Natural Science Foundation of China(T2225003 and 61927805);the Nanjing Medical Science and Technique Development Foundation(ZKX21019);the Clinical Trials from Nanjing Drum Tower Hospital(2022-LCYJ-ZD-01);the Jiangsu Funding Program for Excellent Postdoctoral Talent(2023ZB032);the Natural Science Foundation of Jiangsu Province(BK20240223);the Project of Institute of Chinese Medicine of Nanjing University(ICM2024011);the Aid Project of Nanjing Drum Tower Hospital Health,Education&Research Foundation.
The emerging messenger RNA(mRNA)nanomedicines have sprung up for disease treatment.Developing targeted mRNA nanomedicines has become a thrilling research hotspot in recent years,as they can be precisely delivered to s...
financial support by the Development Plan of Science and Technology of Jilin Province(No.YDZJ202201ZYTS305);the Natural Science Foundation of Jilin Province(No.YDZJ202401316ZYTS);the Innovation Laboratory Development Program of Education Department of Jilin Province and Industry and Information Technology Department of Jilin Province,China(The Joint Laboratory of MAX/MXene Materials).
MAX series materials,as non-van der Waals layered multi-element compounds,contribute remarkable regulated properties and functional dimension,combining the features of metal and ceramic materials due to their inherent...
Spatial memory is crucial for survival within external surroundings and wild environments.The hippocampus,a critical hub for spatial learning and memory formation,has received extensive investigations on how neuromodu...
supported by NEI/NIH R01 EY030513;NIAMS/NIH R21-AR076035;Multi-PI Team Science grant from Presbyterian Health Foundation。
Very long chain-saturated and-polyunsaturated fatty acids(VLC-SFA and VLC-PUFA, respectively) are a functionally important class of fatty acids containing 28 carbons or more in their acyl chain. They are synthesized b...
supported by the National Key Research and Development Program of China(Grant 2021YFA0715600,2021YFA0717700,2018YFB2202900);National Natural Science Foundation of China(52192610,62274127,62374128);the Fundamental Research Funds for the Central Universities,2023 Qinchuangyuan Construction Two Chain Integration Special Project(23LLRH0043);Key Research and Development Program of Shaanxi Province(Grant 2024GX-YBXM-512);Foundation of Zhejiang Provincial Key Lab of Solar Energy Utilization&Energy Saving Technology(ZJS-OP-2020-11);GuangDong Basic and Applied Basic Research Foundation(Grant 2022A1515111220);the fund of the state Key Laboratory of Solidification Processing in NPU(Grant No.SKLSP202317);Young Elite Scientists Sponsorship Program by CAST,Doctoral Student Special Plan.
One of the significant technological challenges in safeguarding electronic devices pertains to the modulation of electromagnetic(EM)wave jamming and the recycling of defensive shields.The synergistic effect of heterod...
Development of the telencephalon relies upon several signaling centers-localized cellular populations that supply secreted factors to pattern the cortical neuroepithelium.One such signaling center is the cortical hem,...
Supported by Shanghai Putuo District R&D Platform Project(2024QX04).
[Objectives]To explore the effects of fermentation process on the content and functions of flavonoids in Gardenia jasminoides.[Methods]G.jasminoides was fermented by microorganisms,and the fermentation process of tota...
Supported by the Science and Technology Planning Projects of Guizhou Province,No.QKHJC-ZK[2022]YB642;Health Research Project of Guizhou Province,No.gzwkj2024-324,and No.gzwkj2024-103;WBE Liver Fibrosis Foundation,No.CFHPC2025028;Beijing Liver and Gallbladder Mutual Aid Public Welfare Foundation Artificial Liver Special Fund,No.iGandanF-1082024-Rgg018;Student Innovation and Entrepreneurship Training Program of Zunyi Medical University,No.S2024106612360.
In this letter,we comment on the article by Xuan Yuan et al,published in the recent issue of the World Journal of Gastroenterology.Mixed lineage kinase domainlike protein(MLKL)exhibits cell-type-specific functions in ...
supported by the National Natural Science Foundation of China(22209055);the China Postdoctoral Science Foundation(2022M721330);the Foshan Postdoctoral Science Foundation(X221081MS210);the Innovation Team of Universities of Guangdong Province(2022KCXTD030);the“Targeted Technology Innovation Initiative”Project at the Foshan National Institute of Innovation(JBGS2024002)。
In pursuit of low cost and long life for lithium-ion batteries in electric vehicles,the most promising strategy is to replace the commercial LiCoO_(2)with a high-energy-density Ni-rich cathode.However,the irreversible...