supported by the National Key Research and Development Program of China(2021YFC2500300,2022YFC2502606);the Grants from the Beijing Municipal Science and Technology Commission(Z221100007422008);Major Program of the National Natural Science Foundation of China(82293630,82293633);CAMS Innovation Fund for Medical Sciences(2022-I2M-C&T-B-121,2023-I2MC&T-B-123);Peking University People’s Hospital Research and Development Funds(RD2023-08);Tongzhou District Distinguished Young Scholars(JCQN2023009);the Fundamental Research Funds for the Central Universities。
We aimed to identify dynamic changes of lysine(K)-specific methyltransferase 2A partial tandem duplications(KMT2A-PTD)before and after haploidentical donor hematopoietic stem cell transplantation(HID HSCT)and explore ...
supported by the Key Program of the National Natural Science Foundation of China(No.81930004);the National Natural Science Foundation of China(No.82170208);Tongzhou District Distinguished Young Scholars(No.JCQN2023009);Plan Project of Tongzhou Municipal Science and Technology(No.KJ2024CX045);Beijing Natural Science Foundation(No.Z230016)。
Objective:We aimed to compare the quality-adjusted time without symptoms or toxicity(Q-TWiST)in acute myeloid leukemia(AML)patients who received haploidentical-related donor(HID)and identical sibling donor(ISD)hematop...
Objective To assess the efficacy of cord blood-assisted haploid peripheral blood stem cell transplantation(haplo-cord-PBSCT) versus unrelated donor peripheral blood stem cell transplantation (UD-PBSCT) in the treatmen...
supported by grants from the National Key Research and Development Program(2022YFC2502700);National Natural Science Foundation of China(82020108003,82370213,82370215,82300242,82070187,82000180);Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD);Jiangsu Provincial Medical Innovation Center(CXZX202201);Excellent Youth Science Fund of Jiangsu Province(BK20211553);Suzhou Science Project(SKY2021104,SKY2021039);Suzhou Science and Technology Project(SLT201911);Translational Research Grant of NCRCH(2021ZKMB01).
Coinfusion of unrelated cord blood(UCB)units in haploidentical hematopoietic cell transplantation(haplo-HCT)(haplo-cord HCT)for hematopoietic malignancies showed promising results in previous reports,but the efficienc...
supported by grants from the Foundation for Innovative Research Groups of the National Natural Science Foundation of China(No.81621001);Peking University People’s Hospital Research and Development Funds(No.RDY2020-01)
To the Editor:Allogeneic hematopoietic stem cell transplantation(allo-HSCT)is one of the most effective options for hematological diseases.However,allo-HSCT treatment can cause serious complications.Post-transplant ki...
BACKGROUND The impact of social determinants of health in allogeneic transplant recipients in low-and middle-income countries is poorly described.This observational study analyzes the impact of place of residence,refe...
Recently,Hsu et al.reported the remission and possible cure of HIV-1 infection in the context of an allogeneic hematopoietic stem cell transplant for the treatment of acute myeloid leukemia(AML).1 This is the fourth c...
BACKGROUND Haploidentical hematopoietic stem cell transplantation(Haplo-HSCT)is often performed in children with hematologic malignancies.Faced with the gap in the literature regarding the approach to experiences rela...
This study was supported by grants from National Key Research and Development Program of China(No.2017YFA0105503);NationalNaturalScience FoundationofChina(No.82020108004);Natural Science Foundation of Chongqing Innovation Group(No.cstc2021jcyj-cxttX0001);2020 Open Project of National Clinical Research Center for Hematological Malignancies(No.2020ZKZC02).
Hematopoietic stem cell transplantation(HSCT)is a highly effective and unique medical procedure for the treatment of most hematological malignancies.The first allogeneic transplantation was performed by E.Donnall Thom...
supported by the Foundation for Innovative Research Groups of the National Natural Science Foundation of China(81621001);the National Natural Science Foundation of China(82100227);the Key Program of National Natural Science Foundation of China(81930004);the National Key Research and Development Program of China(2017YFA0104500)。
In recent decades,haploidentical stem cell transplantation(haplo-SCT)to treat severe aplastic anemia(SAA)has achieved remarkable progress.However,long-term results are still lacking.We conducted a multicenter prospect...