supported by the National Natural Science Foundation of China(No.82160627);the Natural Science Foundation of the Guangxi Autonomous Region(No.2020GXNFSAA297262)。
Objective To explore the protective effects and underlying mechanisms of H_2S against lipid peroxidation-mediated carbonyl stress in the uranium-treated NRK-52E cells.Methods Cell viability was evaluated using CCK-8 a...
supported by the Basic Research Joint Special General Project of Yunnan Provincial Local Universities(part)(No:202301BA070001-029,202301BA070001-044);Yunnan Province High-level Scientific and Technological Talents and Innovation Team Selection Special Young and Middle-aged Academic and Technical Leaders Reserve Talent Project(No:202405AC350067).
Objective:To investigate the protective effects of Lepidium draba L.(L.draba)on cyclophosphamide(CP)-induced hepatotoxicity and nephrotoxicity in rats.Methods:A total of 36 rats were divided into six groups as follows...
Supported by the National Science and Technology Major Project"Key New Drug Development and Manufacture Program"(No.2018ZX09101002-001-002);Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(No.ZYYCXTD-C-202005);Special Research Project on Health for Logistics in the Military(No.23BJZ33);Innovative Research Groups of National Natural Science Foundation of China(No.81721002)。
Objective:To investigate the protective effects of stir-fried Semen Armeniacae Amarum(SAA)against aristolochic acidⅠ(AAⅠ)-induced nephrotoxicity and DNA adducts and elucidate the underlying mechanism involved for en...
In this editorial,we discuss the article by Singh et al published in World Journal of Nephrology,stating the need for timely adjustments in inflammatory bowel disease(IBD)patients'long-term management plans.IBD is chr...
supported by the Fundamental Research Funds for the Department of Education in Heilongjiang Province(Grant No.2020-KYYWF-0037 and No.2019-KYYWF-1277);National Natural Science Foundation of China(No.82103869);Project of Qiqihar Academy of Medical Sciences(Grant No.QMSI2019M-23,No.QMSI2019M-05 and No.2024-ZDPY-003);Technology Plan Joint Guidance Project of Qiqihar(Grant No.LHYD-202007);Doctor Youth Fund of Qiqihar Academy of Medical Sciences(Grant No.QMSI2023B-13);Technology Plan Joint Guidance Project of Qiqihar(Grant No.LSFGG-2024100).
Glyphosate-based herbicides(GBHs)are used for weeding purposes in orchards and rubber plantations,as well as in the cultivation of tea mulberry and genetically modified crops.In recent years,GBH has become the most wi...
supported by National Natural Science Foundation of China(Grant Nos.:22036001 and 22276034).
Triclocarban(TCC)is a common antimicrobial agent that has been widely used in medical care.Given the close association between TCC treatment and metabolic disorders,we assessed whether long-term treatment to TCC at a ...
supported by the National Natural Science Foundation of China(82274014,82330033,82030029,92149304,82101228);the Leading Technology Foundation Research Project of Jiangsu Province(BK20192005,China);National Key R&D Program of China(Nos.2021YFA1101300,2021YFA1101800,and 2020YFA0112503);the Project of State Key Laboratory of Natural Medicines,China Pharmaceutical University(SKLNMZZ202302,China).
Ototoxicity and nephrotoxicity are the most prevalent side effects of aminoglycoside antibiotics(gentamicin,amikacin,neomycin)and platinum anti-tumor drugs(cisplatin,carboplatin).The inner ear and kidney share similar...
supported by the National Natural Science Foundation of China(Nos.52293381 and 52273154);the Key Project of Natural Science Foundation of Zhejiang Province(No.LZ23B040002).
Biofilm-associated bacterial infection brings serious threats to global public health owing to serious antibiotic resistance.It is urgently needed to develop innovative strategies to combat biofilm-associated bacteria...
supported by the National Natural Science Foundation of China(82060598,32260587);the Scientific Research Program of Guizhou Provincial Department of Education(QJJ[2023]019);the Science&Technology Program of Guizhou Province(QKHPTRC-CXTD[2022]014);the Excellent Youth Talents of Zunyi Medical University(17zy-006).
Oleanolic acid(OA)and ursolic acid(UA)are commonly present in the cuticular wax of many edible fruits and medicinal herbs.OA and UA belong to the group of bioactive pentacyclic triterpenoids,exhibiting a wide range of...