云南高校图书馆联盟文献共享服务平台- NEOMYCIN

NEOMYCIN: 作品数：16被引量：32H指数：4; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：郭葆玉徐惠敏陆德如胡宗林孔宪涛更多>>; 相关机构：第二军医大学黑龙江八一农垦大学更多>>; 相关期刊：《Frontiers of Medicine》《Open Journal of Ecology》《Chinese Herbal Medicines》《Science China(Life Sciences)》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金更多>>

Neo I represents a group of transcriptional repressors regulating the biosynthesis of multiple aminoglycosides: 《Science China(Life Sciences)》2024年第12期2761-2770,共10页Yue Li Xiangxi Meng Dong Li Xiulei Xia Jihui Zhang Yihua Chen Huarong Tan; supported by the National Natural Science Foundation of China (32170043,82173720);the National Key Research and Development Program of China (2020YFA0907800)。; In general,the initiation or closure of antibiotic biosynthesis is determined by regulatory proteins,but most of their mechanisms of action remain unknown.The 2-deoxystreptamine-containing aminoglycosides(2-DOS AGs)fo...; 关键词：AMINOGLYCOSIDES NEOMYCIN REGULATION Streptomyces fradiae

PGC-1α-mediated imbalance of mitochondria-lipid droplet homeostasis in neomycin-induced ototoxicity and nephrotoxicity: 《Acta Pharmaceutica Sinica B》2024年第10期4413-4430,共18页Bin Chen Cheng Cheng Yunhao Wu Siyu Li Mo Han Le Zhen Ying Peng Suhan Guo Kaidi Shen Xia Gao Renjie Chai Guangji Wang Fang Zhou; supported by the National Natural Science Foundation of China(82274014,82330033,82030029,92149304,82101228);the Leading Technology Foundation Research Project of Jiangsu Province(BK20192005,China);National Key R&D Program of China(Nos.2021YFA1101300,2021YFA1101800,and 2020YFA0112503);the Project of State Key Laboratory of Natural Medicines,China Pharmaceutical University(SKLNMZZ202302,China).; Ototoxicity and nephrotoxicity are the most prevalent side effects of aminoglycoside antibiotics(gentamicin,amikacin,neomycin)and platinum anti-tumor drugs(cisplatin,carboplatin).The inner ear and kidney share similar...; 关键词：MITOCHONDRIA NEOMYCIN NEPHROTOXICITY OTOTOXICITY Lipid metabolism TRIACYLGLYCEROL PGC-1Α PLIN3

Results of selective decontamination with oral neomycin and metronidazole for major colorectal surgery in Australia:A cohort study: 《Laparoscopic, Endoscopic and Robotic Surgery》2024年第2期72-78,共7页James Wei Tatt Toh Devansh Shah Henry Wang Charlotte Kwik Joseph Do Woong Choi Chelsie Leonie Beinke Paul Morris Eleni Baird-Gunning Geoffrey Peter Collins Fiona Gavegan Karen Shedden Toufic El-Khoury Nimalan Pathma-Nathan Kerry Hitos; Objective The role of selective decontamination with oral antibiotics(OABs)and mechanical bowel preparation(MBP)prior to elective colorectal surgery is still widely debated.The objective of this study was to compare t...; 关键词：NEOMYCIN METRONIDAZOLE Colorectal surgery Anastomotic leakage Surgical site infection

Apigenin alleviates neomycin-induced oxidative damage via the Nrf2 signaling pathway in cochlear hair cells被引量：1: 《Frontiers of Medicine》2022年第4期637-650,共14页Gaogan Jia Huanyu Mao Yanping Zhang Yusu Ni Yan Chen; supported by the National Key R&D Program of China(No.2017YFA0103900);the National Natural Science Foundation of China(Nos.81771010 and 81570911);the Nature Science Foundation(No.17ZR1404600);from Shanghai Science and Technology Committee.; Oxidative stress plays an important role in the pathogenesis of aminoglycoside-induced hearing loss and represents a promising target for treatment.We tested the potential effect of apigenin,a natural flavonoid with a...; 关键词：APIGENIN AMINOGLYCOSIDES OTOTOXICITY oxidative stress Nrf2 signaling pathway

Neomycin biosynthesis is regulated positively by AfsA-g and NeoR in Streptomyces fradiae CGMCC 4.7387被引量：8: 《Science China(Life Sciences)》2017年第9期980-991,共12页Xiangxi Meng Wenzhao Wang Zhoujie Xie Pengwei Li Yue Li Zhengyan Guo Yingjian Lu Jie Yang Kaile Guan Zhaoxin Lu Huarong Tan Yihua Chen; funded in part by the Ministry of Science and Technology of China(2015CB150600);the National Natural Science Foundation of China(31370095 and 31522001); Neomycins are a group of aminoglycoside antibiotics with both clinical and agricultural applications.To elucidate the regulatory mechanism of neomycin biosynthesis,we completed draft genome sequencing of a neomycin pr...; 关键词：NEOMYCIN REGULATION Γ-BUTYROLACTONE STREPTOMYCES

Synergistic Effect of Silver Nanoparticles with Neomycin or Gentamicin Antibiotics on Mastitis-Causing Staphylococcus aureus: 《Open Journal of Ecology》2016年第7期452-459,共9页Shahab Jamaran Bahareh Rahimian Zarif; Objective: Mastitis is one of the most costly diseases in dairy cows, which greatly decreases milk production. Use of antibiotics in cattle leads to antibiotic-resistance of mastitis-causing bacteria. The present stud...; 关键词：Staphylococcus aureus MASTITIS Silver Nanoparticles GENTAMICIN NEOMYCIN Synergistic

Rapid and Sensitive Chemiluminescent Enzyme Immunoassay for the Determination of Neomycin Residues in Milk被引量：5: 《Biomedical and Environmental Sciences》2016年第5期374-378,共5页LUO Peng Jie ZHANG Jian Bo WANG Hua Li CHEN Xia WU Nan ZHAO Yun Feng WANG Xiao Mei ZHANG Hong ZHANG Ji Yue ZHU Lei JIANG Wen Xiao; supported by the project for talent training and development of the China National Center for Food Safety Risk Assessment(523 plan);Natural Science Foundation of Guangdong Province(No.2014A030310289 and No.2016A020210055);Natural Science Foundation of SZU(No.201576);National Natural Science Foundation of China(No.21107104); Immunoassays greatly contribute to veterinary drug residue analysis. However, there are few reports on detecting neomycin residues by immunoassay. Here, a rapid and sensitive chemiluminescent enzyme immunoassay （CLIE...; 关键词：CLEIA Rapid and Sensitive Chemiluminescent Enzyme Immunoassay for the Determination of Neomycin Residues in Milk

Nystatin-Neomycin-Polymyxin B Combination:Efficacy and Tolerance as 1st-Line Local Treatment of Infectious Vaginitis: 《Open Journal of Obstetrics and Gynecology》2014年第7期445-454,共10页Jean-Marc Bohbot Patrice Sednaoui Francois Verriere; Objective: To evaluate the efficacy and tolerance of a local treatment combining two antibacterials and one antifungal in patients with a clinical presentation suggesting infectious vaginitis. Patients and methods: 16...; 关键词：CANDIDIASIS Mixed Vaginitis Bacterial Vaginitis Nystatin Neomycin Polymyxin B Empirical Therapy

Follicular contact dermatitis revisited: A review emphasizing neomycin-associated follicular contact dermatitis被引量：4: 《World Journal of Clinical Cases》2014年第12期815-821,共7页Philip R Cohen; Follicular contact dermatitis clinically presents as individual papules that include a central hair follicle. Pathologic features involve the follicle and the surrounding dermis: spongiosis and vesicle formation of th...; 关键词：ALLERGIC Contact DERMATITIS FOLLICULAR IRRITANT NEOMYCIN PAPULAR

Antibacterial Mechanisms of Berberine and Reasons for Little Resistance of Bacteria被引量：13: 《Chinese Herbal Medicines》2011年第1期27-35,共9页JIN Jian-ling,HUA Guo-qiang,MENG Zhen,GAO Pei-ji State Key Laboratory of Microbial Technology,School of Life Sciences,Shandong University,Jinan 250100,China; The National Natural Sciences of Chinese(81041089); Objective To study the antibacterial mechanisms of berberine and try to understand the reasons why bacteria cells difficultly resisted to it.Methods Detecting the minimal inhibitory concentration(MIC) of bacterial cul...; 关键词：antibacterial effect antibiotic resistance BERBERINE binding kinetics NEOMYCIN

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