GENTAMICIN

作品数：55被引量：65H指数：4
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相关领域：医药卫生更多>>
相关作者：李培忠李忠东孟辉李胜利朱宏亮更多>>
相关机构：中国农业大学聚纳达(青岛)科技有限公司空军总医院军事医学科学院更多>>
相关期刊：《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》《Asian Pacific Journal of Tropical Biomedicine》《Chinese Journal of Chemistry》《Open Journal of Ecology》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金上海市浦江人才计划项目更多>>
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A preliminary study of the mechanism of compound hearing loss caused by ototoxic drugs combined with impulse noise
《iLABMED》2024年第1期38-52,共15页Xin Qiu Qing‐qing Jiang Wei‐wei Guo Ning Yu Shi‐ming Yang 
National Natural Science Foundation of China,Grant/Award Number:81470700;Beijing Municipal Natural Science Foundation,Grant/Award Number:7222185;Key R&D program of Ministry of Science and Technology,Grant/Award Number:2022YFC2402704;National Key Research and Development Program of China,Grant/Award Numbers:2020YFC2004001,2020YFC2005203。
Background:Hearing loss(HL)is becoming increasingly common and is more commonly caused by noise,ototoxic substances,or a combination of ototoxic factors.However,so far,few studies have examined the mechanism by which ...
关键词：auditory brainstem response GENTAMICIN hearing loss impulse noise molecular mechanisms PATHOMORPHOLOGY 
Application of topical gentamicin ointment in the treatment of Nagashima-type palmoplantar keratosis in children with a nonsense mutation被引量：1
《Pediatric Investigation》2023年第3期163-167,共5页Shan Wang Zhou Yang Ying Liu Huan Zhang Zongyang Liu Xiaoling Wang Ying Li Haihong Liu Yonghong Yang Lin Ma 
Children’s Medicine Research Project of Beijing Children’s Hospital,Capital Medical University,Grant/Award Number:YZZD202002
Importance:Nagashima-type palmoplantar keratosis(NPPK)is a hereditary dermatosis mostly caused by a nonsense mutation in SERPINB7.Despite the increasing interest in readthrough gentamicin treatment of NPPK,clinical ev...
关键词：CHILDREN GENTAMICIN Nagashima-type palmoplantar keratosis Nonsense mutation Readthrough treatment 
Is fat-free mass-based gentamicin dosing regimen preferable than whole-body weight in neonates?
《Pediatric Investigation》2023年第2期86-94,共9页Kannan Sridharan Muna Al Jufairi Eman Al Ansari Lulwa Alsadah Howra Wasel 
Importance:Body fluid dynamics and renal maturation status vary during the neonatal period.We hypothesized that differences in peak and trough gentamicin concentrations could be expected.Objective:To predict the peak ...
关键词：AMINOGLYCOSIDES Body weight FAT Fat-free mass GENTAMICIN 
Identification of Persister Drug Combination Clinafloxacin+Cefuroxime+Gentamicin That Eradicates Persistent Pseudomonas aeruginosa Infection in a Murine Cystic Fibrosis Model被引量：2
《Infectious Microbes & Diseases》2023年第1期21-28,共8页Yuting Yuan Rebecca Yee Naina Gour Xinzhong Dong Jie Feng Wanliang Shi Ying Zhang 
Pseudomonas aeruginosa can cause persistent infections,such as biofilm infections,in cystic fibrosis patients,which are difficult to cure due to non-growing persister bacteria that are not effectively killed by the cu...
关键词：Pseudomonas aeruginosa persisters stationary-phase bacteria BIOFILM CLINAFLOXACIN cystic fibrosis 
Protective effect of Cistanche deserticola on gentamicin-induced nephrotoxicity in rats被引量：1
《Chinese Herbal Medicines》2023年第1期102-109,共8页Xiaoqing Song Jinying Wang Yu Zhang Xinqian Du Qibing Qian 
supported by the National Key Research and Development Program of China (2018YFC1706300, 2018YFC17063003);the Key Research and Development Project of Gan Su Province (20YF2FA019);the People’s Livelihood Special Project from Technical Innovation Guide Plan of Gansu Province (20CX4FK014);the Key Talent Project of Organization Department of Gansu Provincial Party Committee ([2022]Gan-71);the Talent Innovation and Entrepreneurship Project of Lanzhou (2017-RC115, 2020-RC-41)。
Objective: Gentamicin(GM) is a commonly used aminoglycoside antibiotic, however, renal toxicity has limited its usage. The present study was designed to evaluate the ameliorative effect of Cistanche deserticola on GM-...
关键词：apoptosis Cistanche deserticola Y.C.Ma GENTAMICIN INFLAMMATION NEPHROTOXICITY OROBANCHACEAE oxidative stress 
Effects of Chemical Products on Fire Blight Suppression,and Fruit Production and Quality in Apple(Malus domestica Borkh.)cv.Golden Glory
《Phyton-International Journal of Experimental Botany》2022年第7期1341-1351,共11页Álvaro Rodríguez-Peña Ana C.Gonzalez-Franco Jared Hernández-Huerta Nora A.Salas-Salazar Dámaris L.Ojeda-Barrios Esteban Sánchez Loreto Robles-Hernández 
Antibiotics are widely used in fire blight management programs,yet there are no studies that demonstrate the evaluation of their efficacy in Mexico.Therefore,the present study was conducted to investigate the effects ...
关键词：Erwinia amylovora OXYTETRACYCLINE GENTAMICIN kasugamycin STREPTOMYCIN ACIBENZOLAR-S-METHYL 
Enhanced corrosion resistance,antibacterial activity and biocompatibility of gentamicin-montmorillonite coating on Mg alloy-in vitro and in vivo studies被引量：2
《Journal of Materials Science & Technology》2022年第16期167-180,共14页Lijun Fan Wenxin Sun Yuhong Zou Qian-qian Xu Rong-Chang Zeng Jingrui Tian 
financially supported by the National Natural Science Foundation of China(No.52071191);the Natural Science Foundation of Shandong Province(No.ZR 2020ME011)。
Implant-associate infection(IAI)is a major cause of failure of bone implant materials,and one of the significant challenges in clinical managements.A synergistic coating strategy combining montmorillonite(MMT)sustaine...
关键词：Magnesium alloy MONTMORILLONITE GENTAMICIN Antibacterial activity COATING 
Electrohydrodynamic Fabrication of Triple-layered Polycaprolactone Dura Mater Substitute with Antibacterial and Enhanced Osteogenic Capability
《Chinese Journal of Mechanical Engineering(Additive Manufacturing Frontiers)》2022年第2期66-75,共10页Yanwen Su Zhi Li Hui Zhu Jiankang He Boyuan Wei Dichen Li 
supported by National Key Research and Develop-ment Program of China(Grant No.2018YFA0703000);OPEN Project(Grant No.BHJ17C019),National Natural Science Foundation of China(Grant No.52125501);Key Research Project of Shaanxi Province(Grant Nos.2020GXLH-Y-021,2021GXLH-Z-028);Guangdong Basic and Ap-plied Basic Research Foundation(Grant No.2020B1515130002);Inno-vation Cultivation Fund of the Sixth Medical Center of PLA General Hos-pital(Grant No.CXPY201913);China Postdoctoral Science Foundation Funded Project(Grant No.2021M702597);Youth Innovation Team of Shaanxi Universities and the Fundamental Research Funds for the Central Universities.
In the field of dura mater repair,it is essential to employ artificial substitutes mimicking the multilayered microar-chitecture and multiple functions of native dura mater for effective neurosurgery.However,existing ...
关键词：Dura mater substitute Electrospinning Melt-based electrohydrodynamic printing Gentamicin sulfate NANO-HYDROXYAPATITE 
Application of topical gentamicin-a new era in the treatment of genodermatosis被引量：4
《World Journal of Pediatrics》2021年第6期568-575,共8页Shan Wang Zhou Yang Ying Liu Mu-Tong Zhao Juan Zhao Huan Zhang Zong-Yang Liu Xiao-Ling Wang Lin Ma Yong-Hong Yang 
supported by Children's Medicine Research Project of Beijing Children's Hospital,Capital Medical University(YZZD202002).
Background The clinical use of gentamicin always lies in its antimicrobial activity in the past as an aminoglycoside antibiotic.However,in the past decade,there were considerable interests in therapeutic approaches in...
关键词：Epidermolysis bullosa GENTAMICIN Nagashima-type palmoplantar keratosis Nonsense mutation READTHROUGH 
Antibiotic-loaded amphora-shaped pores on a titanium implant surface enhance osteointegration and prevent infections被引量：4
《Bioactive Materials》2021年第8期2331-2345,共15页Viviane Ständert Kai Borcherding Nicole Bormann Gerhard Schmidmaier Ingo Grunwald Britt Wildemann 
This work was funded by the Federal Ministry of Education and Research,Germany[grant numbers 03VP03681,03VP03682].
Artificial prostheses for joint replacement are indispensable in orthopedic surgery.Unfortunately,the implanted surface is attractive to not only host cells but also bacteria.To enable better osteointegration,a mechan...
关键词：Titanium implants Laser structuring Amphora-shaped pores Gentamicin loading Antimicrobial silver particles 
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