NLRS

作品数：37被引量：186H指数：7
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NLR-mediated antiviral immunity in plants
《Journal of Integrative Plant Biology》2025年第3期786-800,共15页Min Zhu Mingfeng Feng Xiaorong Tao 
supported by the Funds from the National Key Research and Development Program of China(Grant Nos.2022YFF1001500,2022YFD1401200);the National Natural Science Foundation of China(Grant Nos.32272488,31630062,32220103008,32430088,and 32102169);Jiangsu Provincial Key Research and Development Plan(Grant No.BE2022369);the Jiangsu Key Technology R&D Program and International Science and Technology Cooperation Project(Grant Nos.BZ2023030)。
Plant viruses cause substantial agricultural devastation and economic losses worldwide.Plant nucleotide-binding domain leucine-rich repeat receptors(NLRs)play a pivotal role in detecting viral infection and activating...
关键词：downstream immune signaling NLR recognition nucleotide-binding domain leucine-rich repeat receptors(NLRs) plant virus viral effectors 
Transcriptional profiling during infection of potato NLRs and Phytophthora infestans effectors using cDNA enrichment sequencing被引量：1
《The Crop Journal》2025年第1期31-40,共10页Amanpreet Kaur Vikrant Singh Stephen Byrne Miles Armstrong Thomas M.Adams Brian Harrower Eleanor Gilroy Ewen Mullins Ingo Hein 
supported by the Rural & Environment Science & Analytical Services (RESAS) Division of the Scottish Government through project JHI-B1-1;the Biotechnology and Biological Sciences Research Council (BBSRC) through awards BB/ S015663/1;BB/X009068/1;Research Leaders 2025 fellowship funded by European Union’s Horizon 2020 research and innovation programme under Marie Sklodowska-Curie grant agreement no. 754380;the Research/Scientific Computing teams at The James Hutton Institute and NIAB for providing computational resources and technical support for the “UK’s Crop Diversity Bioinformatics HPC” (BBSRC grant BB/ S019669/1)。
An accurate assessment of host and pathogen gene expression during infection is critical for understanding the molecular aspects of host-pathogen interactions.Often,pathogen-derived transcripts are difficult to ascert...
关键词：RxLR effector NLRS Late blight POTATO cDNA sequencing RenSeq PenSeq RNASEQ 
核苷酸结合寡聚化结构域样受体在肝内外缺血再灌注中的研究进展被引量：1
《肝胆胰外科杂志》2024年第9期564-569,共6页陈丰 彭秀达 费书珂 
湖南省自然科学基金项目(2023JJ60354)。
缺血再灌注损伤(IRI)是指器官经历一段时间的缺血缺氧后,随着血液重新灌注器官,出现器官结构和功能损伤进一步加重的现象,在临床中IRI是许多手术患者在围手术期出现并发症的重要原因。尽管过去几十年对IRI的研究从未停止,但IRI的病理生...
关键词：核苷酸结合寡聚结构域样受体(NLRs) 炎症 细胞死亡 缺血再灌注损伤(IRI) 肝脏疾病 
The Role of E3 Ligases in Macrophage-mediated Inflammation
《生物化学与生物物理进展》2024年第9期2037-2060,共24页JIN Jia-Bei GE Yi-Dong JIN Xiao-Feng 
宁波大学“医学部核心课程建设”项目;国家自然科学基金(32270821);宁波市自然科学基金(2021J065);宁波大学王宽诚基金和宁波大学大学生科研创新计划(SRIP)项目(2023SRIP1913)资助。
Macrophages,existed in almost all organs of the body,are responsible for detecting tissue injury,pathogens,playing a key role in host defense against a variety of invading pathogens triggering inflammatory responses.E...
关键词：E3 ligases MACROPHAGE NLRs/RLRs/TLRs targeted therapies 
NLR受体在水稻效应物诱导的免疫中的作用
《农业科学》2024年第5期548-555,共8页班廷烜 
水稻是重要的粮食作物,在自然生长状态下会面临各种病原体、昆虫的侵害。稻瘟病、白叶枯病和褐飞虱虫害是对水稻产量和品质影响最严重的三种水稻病害,每年因各种水稻病害造成大量的粮食损失。植物与病原体长期斗争的过程进化出了植物免...
关键词：水稻 植物免疫 NLRS 
Harnessing nanobodies to expand the recognition spectrumof plant NLRs for diverse pathogens
《aBIOTECH》2023年第3期272-276,共5页Ruyi Wang Guo-Liang Wang Yuese Ning 
supports from the National Natural Science Foundation of China(32001858 and U20A2021)to R.W.;the National Key Research and Development Program(2022YFD1401400);National Natural Science Foundation of China(32161143009)to Y.N.
The strategy to expand the recognition spectrum of plant nucleotide-binding domain leucine-richrepeat (NLR) proteins by modifying their recognition sequences is generally limited and oftenunsuccessful. Kourelis et al....
关键词：NLR Pik NANOBODY Fluorescent protein IMMUNITY 
植物PRRs和NLRs介导的免疫信号通路研究进展被引量：4
《江苏农业科学》2023年第8期43-50,共8页刘艳艳 丁颖 郑佳秋 宛柏杰 曹婷 刘兴华 
江苏省农业科技自主创新资金[编号:CX(21)3031];江苏省农业重大新品种创制项目(编号:PZCZ201715)。
植物在生长发育的过程中进化出大量细胞表面和胞内免疫受体以感知病原体侵染相关的各种信号。细胞表面模式受体PRR可以感知病原物模式分子以激活基础免疫,引起活性氧(ROS)快速产生、Ca2+内流和丝裂原活化蛋白激酶(MAPK)级联反应的启动等...
关键词：植物免疫 PRRS NLRS 分子机制 相互作用 
促性腺激素释放激素激动剂辅助腹腔镜下卵巢囊肿剥离术对患者外周血TNF-α、IL-6、NLRs表达水平的影响
《中国当代医药》2023年第9期94-97,共4页杜林 
目的 探讨腹腔镜下卵巢囊肿剥离术后使用促性腺激素释放激素激动剂(GnRH-a)辅助治疗对患者外周血肿瘤坏死因子-α(TNF-α)与白细胞介素-6(IL-6)及核苷酸结合寡聚域样受体(NLRs)表达水平的影响。方法选取2020年1月至2021年10月哈尔滨市...
关键词：促性腺激素释放激素激动剂 腹腔镜下卵巢囊肿剥离术 肿瘤坏死因子-Α 白细胞介素-6 核苷酸结合寡聚域样受体 
Structure, biochemical function, and signaling mechanism of plant NLRs被引量：6
《Molecular Plant》2023年第1期75-95,共21页Jizong Wang Wen Song Jijie Chai 
Young Elite Scientists Sponsorship Program by CAST(grant YESS20210018 to J.W.);National Natural Science Foundation of China(grant 32271253 to J.W.);Alexander von Humboldt Foundation(professorship to J.C.);Max-Planck-Gesellschaft(a Max Planck fellowship to J.C.);Deutsche Forschungsgemeinschaft(grant SFB-1403-414786233 to J.C.);Germany's Excellence Strategy CEPLAS(EXC-2048/1,project 390686111 to J.C.).
To counter pathogen invasion,plants have evolved a large number of immune receptors,including membrane-resident pattern recognition receptors(PRRs)and intracellular nucleotide-binding and leucine-rich repeat receptors...
关键词：plant immunity PRR NLR resistosome Ca2+-permeable channels Ca2+signaling second messenger 
NLR’s Analogs with Young Blood Cells in Monitoring of Toxicity of Long-Term Preventing Immunosuppression in the Liver Transplant’s Recipients
《Open Journal of Biophysics》2022年第4期173-184,共12页Aleksey N. Shoutko Olga A. Gerasimova 
The blood neutrophils to lymphocytes ratio (NLR) reflects the physiological homeostasis between lymphopoiesis and myelopoiesis, and its elevation serves as a harmful sign in many pathologies, partially, late rejection...
关键词：Liver TRANSPLANTATION Health Late Period MONITORING Stem Progenitor Cells NLR 
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