终池持续引流加鞘内注药对蛛网膜下腔出血治疗的研究  

Study on the effect of continuous terminal cistern drainage of cerebrospinal fluid with joining medicine on the subarachnoid hemorrhage

作　　者：袁军[1] 朱润秀[1] 萨如拉[1] 常虹[1] 

机构地区：[1]内蒙古自治区医院神经内科,内蒙古呼和浩特010017

出　　处：《疾病监测与控制》2008年第12期727-728,共2页Journal of Diseases Monitor and Control

基　　金：内蒙古自治区卫生厅科研基金资助.编号：2005003

摘　　要：目的评价终池持续引流加鞘内注药对蛛网膜下腔出血临床疗效。方法应用终池持续引流加鞘内注药对蛛网膜下腔出血治疗，与终池持续引流组对照。观察两组患者头痛缓解的时间，临床疗效及脑脊液中NO、NOS、ET-1的变化。结果治疗组头痛缓解的时间比对照组降低（P〈0．05），脑血管痉挛、再出血等合并症比对照组降低（P〈0．05）。脑脊液中NO、NOS比对照组降低，ET—1比对照组升高（P〈0．05）。结论终池持续引流加鞘内注药对蛛网膜下腔出血治疗有显著的疗效。Objective To investigate the effect of continuous terminal cistern drainage of cerebrospinal fluid with joining medicine on the subarachnoid hemorrhage.Methods 62 patients were divided randomly into continuous tenninal cistem drainage ofcerebrospinal fluid with joining medicine and without medicine,observe the time of relief of headache and changes of NO, NOS, ET-1 in cerebrospinal fluid. Results the time of headache is more shorter in the group of treatment, cerebral vascular spasm, subarachnoid hemorrhage again are reduced compared with group of control.ConcentrationS of NO, NOS in cerebrospinal fluid are reduced compared with group of control ,,concentration of ET- 1 in cerebrospinal fluid is increased .Conclusion continuous terminal cistern drainage of cerebrospinal fluid with joining medicine is more effective in the treatment of SAH and it can accelerate the recovery of disease.

关 键 词：终池持续引流 蛛网膜下腔出血 

分 类 号：R743.34[医药卫生—神经病学与精神病学]